Clinical Trials for Castration-Resistant Prostate Carcinoma

Find clinical trials for castration-resistant prostate carcinoma. Discover research opportunities and treatment options in your area.

21 Active Trials Found

Showing 21 trials on this page

Page 1 of 2

Imaging of Solid Tumors Using 18F-TRX

NCT ID: NCT06942104

This clinical trial is studying a new imaging agent called 18F-TRX to see how safe and effective it is for detecting tumors in patients with solid cancers. 18F-TRX is a special tracer used during P...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Francisco, California, United States, San Francisco, California, United States

Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

NCT ID: NCT06200103

This clinical trial is studying a new way to use a targeted treatment called 177Lu-PSMA-617 for men with advanced prostate cancer that is no longer responding to hormone therapy and has spread to o...

Recruiting

Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

NCT ID: NCT06632977

The PREDICT Trial is a clinical study designed to explore how genetic testing can help doctors choose the best treatment options for patients with advanced prostate cancer that no longer responds t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Buffalo, New York, United States, Oklahoma City, Oklahoma, United States +41 more

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

NCT ID: NCT04550494

This clinical trial is studying a medication called talazoparib to see how well it works for patients with advanced cancers that have spread in the body and have specific changes in their DNA repai...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States, Oklahoma City, Oklahoma, United States +2 more

Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

NCT ID: NCT05113537

This clinical trial is studying a new treatment approach for men with advanced prostate cancer that has spread to other parts of the body and is no longer responding to standard hormone therapy. Th...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Francisco, California, United States

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

NCT ID: NCT06616155

This clinical trial is studying a combination of two medications, ruxolitinib and enzalutamide, to see if they can be safe and effective for treating advanced prostate cancer that continues to grow...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ann Arbor, Michigan, United States, Chicago, Illinois, United States +1 more

Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study

NCT ID: NCT06039371

The SPECTRA Study is a clinical trial designed to explore whether giving higher levels of testosterone can help improve the effects of chemotherapy in men with advanced prostate cancer that has con...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States

Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease

NCT ID: NCT06526299

The LPS-Boost clinical trial is studying a new treatment for men with advanced prostate cancer that has not responded to standard therapies. Specifically, it is testing a radioactive drug called 17...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States, San Francisco, California, United States +1 more

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

NCT ID: NCT04693377

The CROME Trial is studying a new treatment approach for patients suffering from painful bone metastases, which occur when cancer spreads to the bones. The trial compares two methods: one combines ...

Recruiting

Phase: NA Type: interventional Locations: Houston, Texas, United States

Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy

NCT ID: NCT05398302

This clinical trial is looking at how some patients with metastatic castration-resistant prostate cancer respond to a specific treatment called 177Lu-PSMA radioligand therapy. The researchers want ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Los Angeles, California, United States

Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer, The AtezoCab Trial

NCT ID: NCT05168618

The AtezoCab Trial is a clinical study investigating the effectiveness of two drugs, cabozantinib and atezolizumab, in treating men with advanced prostate cancer that has continued to grow despite ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Salt Lake City, Utah, United States

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

NCT ID: NCT06236139

This clinical trial is exploring a new treatment option for men with advanced prostate cancer that continues to grow despite previous treatments. The study is testing a combination of two therapies...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study

NCT ID: NCT05960578

The TRAMP Study is a clinical trial investigating the effectiveness of two medications, golimumab and apalutamide, for treating men with castration-resistant prostate cancer. This type of cancer co...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

NCT ID: NCT04489719

This clinical trial is studying how well a treatment called radium-223 works for men with advanced prostate cancer that has spread to the bones and is no longer responding to hormone therapy. Prost...

Recruiting

Type: observational Locations: Baltimore, Maryland, United States, Seattle, Washington, United States +2 more

Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer

NCT ID: NCT06305598

This clinical trial is studying a new treatment called bipolar androgen therapy for men with metastatic castration-resistant prostate cancer, which means their cancer has spread and is no longer re...

Recruiting

Phase: PHASE1 Type: interventional Locations: Buffalo, New York, United States

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer

NCT ID: NCT06145633

This clinical trial is studying a new treatment approach for men with a specific type of advanced prostate cancer called PSMA-low metastatic castration-resistant prostate cancer (mCRPC). The trial ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States

CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

NCT ID: NCT05689021

This clinical trial is studying a new treatment combination for men with advanced prostate cancer that no longer responds to hormone therapy and has spread to other parts of the body, particularly ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Scottsdale, Arizona, United States, Jacksonville, Florida, United States +1 more

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

NCT ID: NCT06470243

This clinical trial is studying whether adding a chemotherapy drug called carboplatin to the standard treatment with cabazitaxel can improve outcomes for men with advanced prostate cancer that keep...

Recruiting

Phase: PHASE3 Type: interventional Locations: Chicago, Illinois, United States, Flint, Michigan, United States +172 more

Efficacy of Ra-223 in PSMA PET Optimally Selected Patients

NCT ID: NCT05924672

This clinical trial is studying how effective a treatment called Ra-223 is for men with advanced prostate cancer that has spread to the bones. The trial focuses on using a special type of scan call...

Recruiting

Phase: PHASE2 Type: interventional Locations: San Francisco, California, United States, San Francisco, California, United States

PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer

NCT ID: NCT05805371

This clinical trial is investigating a new treatment for men with castration-resistant prostate cancer that has spread to other parts of the body. The treatment involves using specially modified im...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States

Related Conditions

Breast Cancer View clinical trials → Stroke View clinical trials → Obesity View clinical trials → Cancer View clinical trials → Healthy View clinical trials → Prostate Cancer View clinical trials →

Search All Trials Browse All Conditions