Clinical Trials for Chronic Graft Versus Host Disease

Find clinical trials for chronic graft versus host disease. Discover research opportunities and treatment options in your area.

16 Active Trials Found

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Predicting the Quality of Response to Specific Treatments in Patients With cGVHD, PQRST Study

NCT ID: NCT04431479

The PQRST Study is a clinical trial designed to help doctors understand how well different treatments work for patients with chronic graft-versus-host disease (cGVHD). cGVHD is a condition that can...

Recruiting

Type: observational Locations: Cleveland, Ohio, United States, Buffalo, New York, United States +8 more

Safety and Efficacy of Oral Belumosudil in Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander Male and Female Participants Aged 12 Years and Above With Chronic Graft Versus Host Disease (cGVHD) After At Least 2 Prior Lines of Systemic Therapy

NCT ID: NCT05567406

This clinical trial is studying the safety and effectiveness of a medication called belumosudil for individuals aged 12 and older who have chronic graft versus host disease (cGVHD). The trial speci...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +11 more

Axatilimab for Sclerotic Chronic Graft-versus-Host Disease

NCT ID: NCT07011810

This clinical trial is studying a treatment called axatilimab for patients with chronic graft-versus-host disease (cGVHD), specifically focusing on those who have skin that has become thickened or ...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Tampa, Florida, United States +1 more

Gecacitinib for cGVHD: Safety and Efficacy in Patients After ≥2 Lines of Prior Therapy

NCT ID: NCT07012304

This clinical trial is studying a new medication called gecacitinib to see how safe and effective it is for patients with chronic graft-versus-host disease (cGVHD) who have not responded well to at...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, , China

BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)

NCT ID: NCT05922761

The BEBOP clinical trial is investigating a new medication called belumosudil to see how effective it is in preventing or treating bronchiolitis obliterans syndrome (BOS) in patients who have recei...

Recruiting

Phase: PHASE2 Type: interventional Locations: Ann Arbor, Michigan, United States, Boston, Massachusetts, United States +5 more

Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD

NCT ID: NCT06233110

This clinical trial is studying a combination of two medications, ruxolitinib and fostamatinib, to see if they can help patients with chronic graft-versus-host disease (cGvHD) who haven't responded...

Recruiting

Phase: PHASE1 Type: interventional Locations: Durham, North Carolina, United States

A Long-term Extension Study of PCI-32765 (Ibrutinib)

NCT ID: NCT01804686

This clinical trial is focused on studying the long-term safety and effectiveness of a medication called ibrutinib for patients with various types of blood cancers, including chronic lymphocytic le...

Recruiting

Phase: PHASE3 Type: interventional Locations: Lebanon, New Hampshire, United States, Charlottesville, Virginia, United States +203 more

Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

NCT ID: NCT05996627

This clinical trial is testing a new medication called belumosudil for patients with chronic graft versus host disease (cGVHD), a condition that can occur after stem cell transplants. cGVHD happens...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Boston, Massachusetts, United States +4 more

A Study to Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease.

NCT ID: NCT06143891

This clinical trial is studying a new oral medicine called Belumosudil, used together with corticosteroids to treat newly diagnosed chronic graft versus host disease (cGVHD) in patients aged 12 and...

Recruiting

Phase: PHASE3 Type: interventional Locations: Buenos Aires, , Argentina, Leuven, , Belgium +289 more

Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease

NCT ID: NCT06663722

This clinical trial is studying a new treatment for chronic Graft-versus-Host Disease (cGVHD), a condition that can occur after a stem cell or bone marrow transplant. The researchers want to find o...

Recruiting

Phase: PHASE2 Type: interventional Locations: Miami, Florida, United States

Upfront Ruxolitinib for Chronic Graft-vs-host Disease

NCT ID: NCT06695507

This clinical trial is studying a medication called ruxolitinib for treating chronic graft-versus-host disease (cGVHD), a condition that can occur after a stem cell transplant. In this trial, resea...

Recruiting

Phase: PHASE1 Type: interventional Locations: Cincinnati, Ohio, United States

Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease

NCT ID: NCT06046248

This clinical trial is studying the combined effects of two medications, belumosudil and rituximab, as a first-line treatment for a condition called chronic graft-versus-host disease (cGVHD). cGVHD...

Recruiting

Phase: PHASE2 Type: interventional Locations: Atlanta, Georgia, United States

A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease

NCT ID: NCT06300320

This clinical trial is studying a new medication called TQ05105 tablets to see how well it works and how safe it is for people with chronic graft-versus-host disease (cGVHD). cGVHD can occur after ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Nanning, Guangxi, China, Shijiazhuang, Hebei, China +12 more

Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant

NCT ID: NCT06271616

This clinical trial is studying the use of a medication called ibrutinib to see if it can help prevent a condition known as chronic graft-versus-host disease (cGVHD) in patients who have received a...

Recruiting

Phase: PHASE2 Type: interventional Locations: Jacksonville, Florida, United States

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

NCT ID: NCT05993611

This clinical trial is studying a new treatment for patients with chronic graft-versus-host disease (cGVHD), a condition that can occur after receiving a stem cell transplant. This condition happen...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States

Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD)

NCT ID: NCT06247150

This clinical trial, called TIL-GVHD, is studying a condition known as Chronic Graft Versus Host Disease (cGVHD), which can occur after a type of cancer treatment called allogeneic stem cell transp...

Recruiting

Phase: NA Type: interventional Locations: Pessac, , France

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