Clinical Trials for Colorectal Cancer

Find clinical trials for colorectal cancer. Discover research opportunities and treatment options in your area.

634 Active Trials Found

Showing 634 trials on this page

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PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

NCT ID: NCT05286814

This clinical trial is studying a new treatment approach for patients with specific types of liver cancer, including metastatic colorectal cancer (which has spread to the liver) and intrahepatic ch...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

NCT ID: NCT03998202

This clinical trial is investigating how low muscle mass, also known as myopenia, affects older adults with advanced colorectal cancer when they receive chemotherapy. Researchers want to understand...

Recruiting

Type: observational Locations: Flint, Michigan, United States, Edina, Minnesota, United States +211 more

ASPEN-09: A Study of Evorpacept in Combination With Anti-cancer Therapies in Advanced / Metastatic Malignancies

NCT ID: NCT07007559

The ASPEN-09 clinical trial is studying a new treatment called evorpacept, which is being tested alongside standard anti-cancer therapies for patients with advanced cancers, specifically metastatic...

Recruiting

Phase: PHASE1 Type: interventional Locations: Canton, Ohio, United States

SAMe in Prevention of Oxaliplatin-associated Liver Injury

NCT ID: NCT06258525

This clinical trial is looking into whether a supplement called S-adenosylmethionine (SAMe) can help prevent liver damage caused by a chemotherapy drug called oxaliplatin in patients with colorecta...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Los Angeles, California, United States, Los Angeles, California, United States

Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.

NCT ID: NCT05649072

This clinical trial is focused on identifying women who may have a higher risk for certain hereditary cancers, such as ovarian, breast, and colorectal cancer. The study uses mobile mammography unit...

Recruiting

Phase: NA Type: interventional Locations: Houston, Texas, United States

A Study of Hansoh (HS)-10502 in Patients With Advanced Solid Tumors

NCT ID: NCT05740956

This clinical trial is studying a new treatment called HS-10502 for patients with advanced solid tumors, including ovarian, breast, pancreatic, prostatic, and colorectal cancers. HS-10502 is design...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China

Exploratory Study of Precise Therapy for Advanced Tumor Patients With Malignant Hydrothorax or Ascites by Using PTC Drug Sensitivity Testing

NCT ID: NCT06413212

This clinical trial is looking at a new way to find the most effective treatments for patients with advanced cancers, such as lung, breast, gastric, and colorectal cancer, who are experiencing flui...

Recruiting

Type: observational Locations: Wuhan, Hubei, China

A Clinical Study of MK-2870 Alone or With Chemotherapy to Treat Gastrointestinal Cancers (MK-9999-02A)

NCT ID: NCT06428409

This clinical trial is investigating a new treatment called sacituzumab tirumotecan (MK-2870) to see how well it works alone or in combination with chemotherapy for certain advanced gastrointestina...

Recruiting

Phase: PHASE1 Type: interventional Locations: Brisbane, Queensland, Australia, Fuzhou, Fujian, China +58 more

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

NCT ID: NCT06358430

This clinical trial is studying a new treatment approach for patients with colorectal cancer (CRC) who have minimal residual disease (MRD), meaning there are no visible signs of cancer but some can...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment

NCT ID: NCT06617858

This clinical trial is studying a new treatment called AMB-05X for patients with colorectal cancer (CRC) who have undergone curative treatment but still show signs of minimal residual disease, indi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

NCT ID: NCT05489211

The TROPION-PanTumor03 clinical trial is exploring a new treatment called Datopotamab Deruxtecan (Dato-DXd) for patients with advanced solid tumors, including types of cancer like endometrial, gast...

Recruiting

Phase: PHASE2 Type: interventional Locations: Barcelona, , Spain, Los Angeles, California, United States +97 more

Iron-deficiency Anaemia and Its Impact on Recovery After Colorectal Cancer Surgery

NCT ID: NCT06276140

This clinical trial is looking at how iron deficiency anaemia affects recovery after surgery for colorectal cancer. Specifically, the researchers want to find out if having low iron before surgery ...

Enrolling by invitation

Type: observational Locations: Sremska Kamenica, , Serbia

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

NCT ID: NCT06695845

This clinical trial is studying a new treatment called zanidatamab for patients with certain types of solid tumors that have high levels of a protein called HER2. These tumors include breast, gastr...

Recruiting

Phase: PHASE2 Type: interventional Locations: Detroit, Michigan, United States, Houston, Texas, United States +19 more

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

NCT ID: NCT06244771

This clinical trial is studying a new treatment called FMC-376 for patients with advanced solid tumors that have a specific genetic change known as the KRAS G12C mutation. These tumors can include ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Detroit, Michigan, United States +13 more

Implementing a Randomized Control Trial to Test the Expanded Web-based Decision Aid

NCT ID: NCT06910670

This clinical trial is testing a new online tool designed to help patients with certain rare cancers—specifically cholangiocarcinoma, colorectal cancer, and multiple myeloma—make important decision...

Recruiting

Phase: NA Type: interventional Locations: Saint Louis, Missouri, United States

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

NCT ID: NCT06205836

This clinical trial is exploring the safety and effectiveness of two treatments, cemiplimab alone and a combination of cemiplimab and fianlimab, for older patients with a type of colorectal cancer ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Baltimore, Maryland, United States

FOLFOXIRI Plus Bevacizumab With or Without Atezolizumab as 1st Line Treatment of pMMR and IS IC-High Metastatic Colorectal Cancer Patients.

NCT ID: NCT06733038

This clinical trial is studying a combination treatment for patients with a specific type of advanced colorectal cancer that has not been treated before. The researchers want to see if adding a med...

Recruiting

Phase: PHASE3 Type: interventional Locations: Milan, Mi, Italy, Lucca, Lu, Italy +17 more

Efficacy of Hyperthermic Intraperitoneal Chemotherapy

NCT ID: NCT04861558

This clinical trial is investigating a treatment approach for patients with colorectal cancer that has spread to the lining of the abdomen, known as peritoneal metastases. The study aims to compare...

Recruiting

Phase: PHASE3 Type: interventional Locations: Uppsala, , Sweden, Malmö, , Sweden +4 more

Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients

NCT ID: NCT06280495

This clinical trial is studying a new treatment approach for patients with colorectal cancer that has spread to the liver. Researchers want to find out if adding two medications, Serplulimab (which...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, , China, Guangzhou, Guangdong, China

Fruquintinib/Regorafenib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Metastatic Colorectal Cancer (FREST-CRC)

NCT ID: NCT06356584

This clinical trial is exploring a new treatment approach for advanced metastatic colorectal cancer (CRC), which is cancer that has spread beyond the colon and rectum. The study is testing a combin...

Recruiting

Phase: PHASE2 Type: interventional Locations: Jinan, Shandong, China

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