Clinical Trials for Colorectal Carcinoma

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients, CORAL Study

NCT ID: NCT05410977

The CORAL Study is a clinical trial aimed at finding better ways to detect colorectal cancer in patients with Lynch syndrome, a genetic condition that increases the risk of developing certain types...

Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery

NCT ID: NCT06935708

This clinical trial is studying two different ways to manage pain after open surgery for colorectal cancer. Researchers want to compare intrathecal morphine, which is a single injection in the spin...

Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer

NCT ID: NCT04812912

This clinical trial is studying how cancer treatments, like chemotherapy and radiation therapy, affect reproductive and sexual health in younger people diagnosed with colorectal cancer. The researc...

CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors

NCT ID: NCT06937567

This clinical trial is studying a new treatment called UCLH801 cells, a type of CAR-T cell therapy, that targets a specific protein (CDH17) found in certain advanced cancers, including biliary trac...

Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery

NCT ID: NCT06926374

This clinical trial is studying a new robotic surgical system called the Sentire Robotic Surgical System, which is designed to help perform major surgeries for conditions like colorectal cancer, pr...

Testing ONC201 to Prevent Colorectal Cancer

NCT ID: NCT05630794

This clinical trial is investigating a new treatment called ONC201 to see if it can help prevent colorectal cancer in people who are at high risk, specifically those with a condition known as famil...

SCRT-CAPEOX-Serplulimab for MSS/pMMR Rectal Cancer With Oligometastases

NCT ID: NCT06850103

This clinical trial, named SCRT-CAPEOX-Serplulimab, focuses on finding a new treatment for patients with a specific type of rectal cancer that has spread to a small number of other places in the bo...

The Ohio State University (OSU) SCREEN Community Program

NCT ID: NCT06666192

The Ohio State University (OSU) SCREEN Community Program is a clinical trial aimed at increasing the number of women who get screened for breast, cervical, and colorectal cancers. These cancers can...

A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products

NCT ID: NCT06885424

This clinical trial is designed to follow up with patients who have previously received gene therapy products from A2 Biotherapeutics for various types of solid tumors, including cancers like color...

Development and Validation of a Blood Test for Early Diagnosis of Colorectal Cancer

NCT ID: NCT06889883

This clinical trial is focused on developing a new blood test that could help detect colorectal cancer and advanced adenomas (which are growths that can lead to cancer) at an early stage. Researche...

Study of JANX008 in Subjects with Advanced or Metastatic Solid Tumor Malignancies

NCT ID: NCT05783622

This clinical trial is studying a new treatment called JANX008 for adults with advanced or metastatic solid tumors, such as certain types of lung cancer, kidney cancer, and breast cancer. The aim i...

A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial

NCT ID: NCT06822530

The PROACT Trial is a study designed to find out if a special program can help more people follow up on abnormal results from a non-invasive colorectal cancer screening test called the fecal immuno...

Evaluation of PreveCol's Efficiency As a Second Line Method for the Early Colorectal Cancer Detection

NCT ID: NCT06703632

This clinical trial is studying a test called PreveCol® to see if it can effectively help detect colorectal cancer and advanced precancerous conditions in people who have already received a positiv...

Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.

NCT ID: NCT06640166

This clinical trial is studying a combination of three treatments—encorafenib, cetuximab, and FOLFIRI—in patients with a specific type of advanced colorectal cancer that has a BRAF V600E mutation. ...

Survivorship Care Plans and Telehealth Education for the Improvement of Access to Cancer Survivorship, the IMPACT Study

NCT ID: NCT04081779

A Web-Based Dyadic Intervention for Colorectal Cancer

NCT ID: NCT05663203

This clinical trial is looking at a new online program designed to help both patients with colorectal cancer and their caregivers manage difficult symptoms that often come with the disease and its ...

The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Injectable SPN01 in Phase I.

NCT ID: NCT06710561

This clinical trial is studying a new injectable treatment called SPN01 for people with colorectal cancer. The main goal is to see if SPN01 is safe and how well it is tolerated by patients. The res...

Clinical Research on the Treatment Model of Ambulatory Surgery for Colorectal Cancer

NCT ID: NCT06637215

This clinical trial is studying a type of surgery called laparoscopic colorectal day surgery to see how well it works and how many complications patients experience after the procedure. This surger...

COLORECTUM+ Digital System for Postoperative Quality Improvement in Colorectal Cancer

NCT ID: NCT06685497

The COLORECTUM+ trial is a study designed to improve the care of patients who have had surgery for colorectal cancer. It will involve 236 participants who will be followed for a year after their su...

Phase 1 Dose Escalation and Expansion to Evaluate AROG4-01 in Patients With Advanced Solid Tumors

NCT ID: NCT06652529

This clinical trial is testing a new drug called AROG4-01 to see if it is safe and effective for patients with advanced solid tumors, such as mesothelioma, colorectal cancer, ovarian cancer, and ad...