Clinical Trials for Diffuse Large B Cell Lymphoma

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT ID: NCT05006716

This clinical trial is studying a new treatment called BGB-16673 for patients with specific types of B-cell cancers, such as Marginal Zone Lymphoma, Follicular Lymphoma, and Chronic Lymphocytic Leu...

A Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma

NCT ID: NCT04594642

This clinical trial is testing a new treatment called AZD0486 for patients with certain types of B-cell non-Hodgkin lymphoma (B-NHL), which is a type of cancer that affects the lymphatic system. Sp...

SynKIR-310 for Relapsed/Refractory B-NHL

NCT ID: NCT06544265

The SynKIR-310 trial is a research study aimed at evaluating a new treatment called SynKIR-310 for adults with certain types of B-cell lymphoma that have not responded to previous therapies or have...

Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy

NCT ID: NCT05757219

This clinical trial is studying a medication called itacitinib to see how safe and effective it is for patients with diffuse large B-cell lymphoma (DLBCL) who are about to receive a type of treatme...

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

NCT ID: NCT03226704

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

NCT ID: NCT06533579

This clinical trial is studying a new treatment called VNX-101 for patients with a type of blood cancer known as B-cell acute lymphoblastic leukemia (ALL) that has not responded to previous therapi...

A Study of Circulating Tumor DNA (ctDNA) Testing for People With B-Cell Lymphoma

NCT ID: NCT06736613

This clinical trial is studying a specific test called circulating tumor DNA (ctDNA) testing for people with B-cell lymphoma, which is a type of cancer that affects the immune system. The main goal...

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies

NCT ID: NCT06227026

This clinical trial is exploring a new treatment using specialized immune cells, called CAR-T cells, to help patients with certain blood cancers that have come back after previous treatments. The s...

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

NCT ID: NCT04104776

This clinical trial is investigating a new treatment called CPI-0209 for patients with advanced solid tumors and lymphomas, including various types of cancer such as lymphoma and mesothelioma. CPI-...

Clinical Trial of TQB2825 Injection Combined Immunochemotherapy in Subjects With Diffuse Large B Cell Lymphoma

NCT ID: NCT06829771

This clinical trial is looking at a new treatment called TQB2825 injection, which is combined with immunochemotherapy to see how well it works for patients with diffuse large B-cell lymphoma (DLBCL...

Phase 1/2 Study of CD19 Chimeric Antigen Receptor T-cell (CD19 CAR-T; PL001) for Relapsed or Refractory B-cell Lymphoma

NCT ID: NCT05326243

This clinical trial is studying a new treatment called CD19 CAR-T (PL001) for patients with advanced types of B-cell lymphoma, such as diffuse large B-cell lymphoma and follicular lymphoma. The fir...

Long-term Follow-up Study of Lentiviral-based Gene-edited Immune Cell Therapy

NCT ID: NCT05377307

This clinical trial is looking at the long-term effects of a new type of treatment called lentiviral-based gene-edited immune cell therapy for patients with certain types of lymphoma, which is a fo...

CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies

NCT ID: NCT06208735

This clinical trial, called CLIC-2201, is exploring a new treatment for patients with certain types of B-cell cancers, such as B-cell leukemia and non-Hodgkin's lymphoma, that have either come back...

Study of IOMAB-ACT Followed by CAR-T Cell Therapy for Patients Relapsed or Refractory (Diffuse Large B-cell Lymphoma

NCT ID: NCT06768905

This clinical trial is investigating a new treatment approach for patients with relapsed or refractory diffuse large B-cell lymphoma, which is a type of non-Hodgkin lymphoma. The study will look at...

Mosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell Lymphoma

NCT ID: NCT05412290

This clinical trial is investigating a new treatment called mosunetuzumab for patients with aggressive B cell lymphomas, which are types of cancer affecting the lymphatic system. The study aims to ...

Mixed Molecular Clinical Index (MMCI) in Diffuse Large B-cell Lymphoma (DLBCL)

NCT ID: NCT04300101

This clinical trial is studying Diffuse Large B-cell Lymphoma (DLBCL), a type of cancer that affects the lymphatic system. The goal is to find new markers, called biomarkers, that can help predict ...

Tazemetostat and Venetoclax in Relapsed/Refractory Non-Hodgkin Lymphoma

NCT ID: NCT05618366

This clinical trial is studying the combination of two medications, tazemetostat and venetoclax, to see how they work together in treating patients with relapsed or refractory Non-Hodgkin Lymphoma,...

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

NCT ID: NCT06131801

This clinical trial is studying how well venetoclax, a medication used to treat certain types of blood cancers like leukemia and lymphoma, works when the tablets are crushed and dissolved in liquid...

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

NCT ID: NCT06022029

This clinical trial is studying a new treatment called ONM-501, which can be given alone or combined with another medication called cemiplimab, for patients with advanced solid tumors and lymphomas...

Study of the Monoclonal Antibody IMT-009 in Patients with Advanced Solid Tumors or Lymphomas

NCT ID: NCT05565417

This clinical trial is studying a new treatment called IMT-009, which is a monoclonal antibody being given to patients with advanced cancers, including types like non-small cell lung cancer, breast...