Clinical Trials for EGFR Activating Mutation

A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer

NCT ID: NCT06685718

This clinical trial is studying a new treatment called BG-60366 for adults with a specific type of lung cancer known as non-small cell lung cancer (NSCLC) that has a mutation in the epidermal growt...

CSF Analysis in EGFR Mutant Non-Small Cell Lung Cancer with Leptomeningeal Disease

NCT ID: NCT05257967

This clinical trial is studying patients with a type of lung cancer called EGFR mutant non-small cell lung cancer (NSCLC) that has spread to the protective layers around the brain and spinal cord, ...

Plasma Exosomes Reveal the Efficacy of Targeted Therapy in Patients With EGFR Mutation in Lung Adenocarcinoma

NCT ID: NCT06730477

TY-9591 in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases

NCT ID: NCT05948813

This clinical trial is investigating a new medication called TY-9591 for patients with advanced non-small cell lung cancer (NSCLC) that has spread to the brain and has specific genetic changes know...

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial

NCT ID: NCT06363734

This clinical trial is testing a new treatment combination of two drugs, osimertinib and dalpiciclib, for patients with advanced non-small cell lung cancer (NSCLC) who have specific genetic changes...

A Prospective Cohort Study to Evaluate Molecular pRognostic Factors and Resistance Mechanisms to Osimertinib in Adjuvant Treatment of Completely Resected pIB-IIIA Non-small Cell Lung Carcinoma With Common EGFR Mutations (L858R and Del19)

NCT ID: NCT06053099

The IFCT-2202 ROSIE study is researching how certain genetic factors affect the outcome of patients with non-small cell lung cancer (NSCLC) who have undergone surgery to remove their tumors and hav...

Phase III Study of TY-9591 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLETEO)

NCT ID: NCT05382728

This clinical trial, called the FLETEO study, is testing a new medication called TY-9591 to see how well it works compared to an existing treatment called Osimertinib for patients with a type of lu...

Early or Delayed Intervention of Brain Radiotherapy Combined With Almonertinib in EGFR Mutated NSCLC With Brain Metastases

NCT ID: NCT05768490

This clinical trial is looking at how timing affects the treatment of brain metastases in patients with non-small cell lung cancer (NSCLC) who have a specific genetic mutation called EGFR. The stud...

Safety and Efficacy of Aumolertinib Combined With Anlotinib as 1st Line Treatment in Advanced Lung Cancer EGFR Mutation With TP53 Co-Mutation

NCT ID: NCT05778149

This clinical trial is investigating the safety and effectiveness of two medications, Aumolertinib and Anlotinib, used together as a first-line treatment for patients with advanced non-small cell l...