Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia With an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients With Post-Menopausal Bleeding

NCT ID: NCT06365905

This clinical trial is studying whether artificial intelligence (AI) can help detect endometrial cancer or its early warning signs in women who have experienced post-menopausal bleeding (PMB). The ...

Recruiting

Type: observational Locations: Scottsdale, Arizona, United States, Jacksonville, Florida, United States +1 more

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

NCT ID: NCT05256225

This clinical trial is studying the effects of adding two targeted therapies, trastuzumab (also known as Herceptin) and pertuzumab, to standard chemotherapy for women with certain types of uterine ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Chicago, Illinois, United States, New Haven, Connecticut, United States +435 more

FOG-001 in Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT05919264

This clinical trial, called FOG-001, is investigating a new treatment for people with advanced or metastatic solid tumors, which are types of cancer that have spread beyond their original site. The...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States +9 more

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

NCT ID: NCT02628067

This clinical trial is studying a medication called pembrolizumab (MK-3475) for people with advanced solid tumors that have not responded to standard treatments. The trial aims to see how well this...

Recruiting

Phase: PHASE2 Type: interventional Locations: North Ryde, , Australia, Midrand, , South Africa +29 more

A Beta-only IL-2 ImmunoTherapY Study

NCT ID: NCT05086692

This clinical trial, called the Beta-only IL-2 ImmunoTherapY Study, is looking to test a new treatment called MDNA11 for patients with advanced solid tumors, which are types of cancer that have spr...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Diego, California, United States, Baltimore, Maryland, United States +31 more

Molecular and ctDNA Characterization of High-Risk Endometrial Cancer

NCT ID: NCT07062016

This clinical trial is studying high-risk endometrial cancer, a type of cancer that starts in the lining of the uterus. The main goal is to learn more about why this cancer sometimes comes back aft...

Not yet recruiting

Type: observational Locations: Scottsdale, Arizona, United States, Jacksonville, Florida, United States +1 more

An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study

NCT ID: NCT06855706

The "Life on the Go 3 Study" is a clinical trial designed to see how a personalized physical activity program, supported by wearable technology, can help improve the health and quality of life for ...

Recruiting

Phase: NA Type: interventional Locations: Buffalo, New York, United States

Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer

NCT ID: NCT04567771

This clinical trial is looking at two types of radiation therapy—proton therapy and intensity-modulated radiation therapy (IMRT)—to see which one causes fewer side effects for women who have had su...

Recruiting

Phase: NA Type: interventional Locations: Scottsdale, Arizona, United States, Jacksonville, Florida, United States +1 more

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

NCT ID: NCT05078047

This clinical trial is investigating whether a less frequent administration of immunotherapy (IO) can be just as effective as the standard treatment schedule for patients with certain types of adva...

Recruiting

Phase: PHASE3 Type: interventional Locations: Nice, , France, Rennes, , France +38 more

Patient Journey in Advanced Gynecologic Cancers

NCT ID: NCT07015593

This clinical trial, titled "Patient Journey in Advanced Gynecologic Cancers," is designed to better understand the experiences of women diagnosed with advanced cervical or endometrial cancer. The ...

Not yet recruiting

Type: observational Locations: Hefei, Anhui, China, Guangzhou, Guangdong, China +2 more

A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer

NCT ID: NCT05691010

This clinical trial is studying a new treatment approach for women with stage III endometrial cancer, which is a type of cancer that affects the lining of the uterus. The researchers want to find o...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: New York, New York, United States, Harrison, New York, United States +8 more

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

NCT ID: NCT05950464

This clinical trial is looking at the safety and effectiveness of two drugs, M1774 and ZEN-3694, when used together to treat women with recurrent ovarian and endometrial cancer. The goal is to find...

Recruiting

Phase: PHASE1 Type: interventional Locations: Cleveland, Ohio, United States, Milwaukee, Wisconsin, United States +12 more

Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

NCT ID: NCT04576104

This clinical trial is looking at whether a medication called megestrol acetate, used alone or with another drug called metformin, can help prevent the progression of a uterine pre-cancer condition...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States, Durham, North Carolina, United States +6 more

Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer

NCT ID: NCT06253494

This clinical trial is studying a new treatment approach for people with advanced or metastatic endometrial cancer, particularly those whose cancer shows higher levels of a protein called HER2. The...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

First-line Carboplatin and Paclitaxel in Combination With Pembrolizumab, Followed by Maintenance Pembrolizumab With or Without Nesuparib, in Patients With Newly Diagnosed Advanced or Recurrent MMR-proficient (pMMR) Endometrial Cancer

NCT ID: NCT06502743

This clinical trial is investigating a new treatment approach for women with advanced or recurrent endometrial cancer, specifically focusing on a combination of two drugs, pembrolizumab and nesupar...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seoul, , Korea, Republic Of, Seoul, , Korea, Republic Of +4 more

A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma

NCT ID: NCT04251416

This clinical trial is studying a new treatment called sacituzumab govitecan (IMMU-132) for women with persistent or recurrent endometrial carcinoma, which is a type of cancer that starts in the li...

Recruiting

Phase: PHASE2 Type: interventional Locations: New Haven, Connecticut, United States

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

NCT ID: NCT05059444

The ORACLE trial is investigating a new blood test developed by Guardant Health that looks for small pieces of cancer DNA in the blood, known as ctDNA, in patients who have been treated for early-s...

Recruiting

Type: observational Locations: Sacramento, California, United States, Boston, Massachusetts, United States +55 more

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

NCT ID: NCT04851119

This clinical trial is studying a new medication called tegavivint, which is being tested to see if it can help patients with certain types of solid tumors that have either come back after treatmen...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Saint Louis, Missouri, United States +20 more

Clinicopathological Analysis of Endometrial Carcinoma in the View of Old and New International Federation of Gynecology and Obestetrics (FIGO)

NCT ID: NCT06632431

This clinical trial is looking at how changes in the staging system for endometrial cancer—specifically, the shift from the FIGO 2009 system to the updated FIGO 2023 system—affect how doctors under...

Recruiting

Type: observational Locations: Assiut, , Egypt

Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma

NCT ID: NCT05316467

This clinical trial is looking at how effective a combination of weight management and a medication called megestrol acetate is for women who are overweight or obese and have early-stage endometria...

Recruiting

Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China

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Clinical Trials for Endometrial Carcinoma

27 Active Trials Found

Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia With an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients With Post-Menopausal Bleeding

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

A Beta-only IL-2 ImmunoTherapY Study

Molecular and ctDNA Characterization of High-Risk Endometrial Cancer

An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study

Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Patient Journey in Advanced Gynecologic Cancers

A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer

First-line Carboplatin and Paclitaxel in Combination With Pembrolizumab, Followed by Maintenance Pembrolizumab With or Without Nesuparib, in Patients With Newly Diagnosed Advanced or Recurrent MMR-proficient (pMMR) Endometrial Cancer

A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Clinicopathological Analysis of Endometrial Carcinoma in the View of Old and New International Federation of Gynecology and Obestetrics (FIGO)

Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma

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