Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade Glioma

NCT ID: NCT07031765

This clinical trial, called Peds CHAMP1ON, is studying a new treatment approach for children and young adults who have certain types of high-grade brain tumors that have come back or are not respon...

Not yet recruiting

Phase: PHASE1 Type: interventional

PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma

NCT ID: NCT06639607

This clinical trial is investigating a new treatment approach for children and young adults with certain types of brain tumors, specifically diffuse midline gliomas (DMG), high-grade gliomas (HGG),...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Durham, North Carolina, United States, Saint Louis, Missouri, United States +1 more

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

NCT ID: NCT03750513

This clinical trial is studying a new type of radiation therapy called LET optimized image modulated proton therapy (IMPT) to treat children with a type of brain tumor called ependymoma. The goal i...

Clinical Trials for Ependymoma

25 Active Trials Found

Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade Glioma

PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Systemic Biomarkers to Predict Radiation-Induced Neurocognitive Decline

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Pharmacoscopy for Patients with Refractory Primary Brain Tumors

Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification

Immunotherapy for Recurrent Ependymomas in Children Using Tumor Antigen Peptides with Imiquimod

Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology

A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2

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