Clinical Trials for Glioblastoma Multiforme

MRI Hypoxia Study for Glioblastoma Multiforme (GBM) Radiation Therapy

NCT ID: NCT05500612

The MRI Hypoxia Study is a clinical trial aimed at improving treatment for patients with Glioblastoma Multiforme (GBM), a type of aggressive brain tumor. This study will explore new imaging techniq...

T Cells and Pembrolizumab for Recurrent and Newly Diagnosed Glioblastoma

NCT ID: NCT06157541

This clinical trial is investigating a new treatment approach for patients with a serious type of brain cancer called glioblastoma multiforme, also known as grade IV astrocytoma. The study is testi...

IA Carboplatin + Radiotherapy in Relapsing GBM

NCT ID: NCT03672721

This clinical trial is studying a new treatment approach for patients with relapsed glioblastoma multiforme (GBM), a type of brain cancer. After the standard treatments (surgery, radiation, and che...

Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With Glioblastoma

NCT ID: NCT06418113

This clinical trial is studying a treatment approach called neoadjuvant radio-chemotherapy for patients with glioblastoma, a type of aggressive brain cancer. The main goals are to see how safe this...

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

NCT ID: NCT03175224

The APL-101 clinical trial is exploring a new treatment for patients with advanced lung cancer, specifically those with certain genetic changes called c-Met Exon 14 skipping mutations or MET amplif...

Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

NCT ID: NCT06329570

This clinical trial is exploring the safety and effectiveness of a treatment combining Bevacizumab (a standard medication for recurrent glioblastoma) with a new technology called the NaviFUS System...

NanoTherm In Adjuvant Therapy of Glioblastoma Multiforme

NCT ID: NCT06271421

The NanoTherm trial is studying a new treatment option for patients with recurrent glioblastoma multiforme (GBM), which is a serious type of brain tumor. This trial aims to find out how well the Na...

Acetyl-Amantadine as a Biomarker in Patients With Glioblastoma

NCT ID: NCT04530006

This clinical trial is studying a medication called acetyl-amantadine to see if it can help monitor glioblastoma multiforme (GBM), which is a serious type of brain tumor. Researchers want to find o...

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

NCT ID: NCT06283927

The RECSUR study is looking at the best ways to treat patients whose glioblastoma, a type of brain cancer, has come back after initial treatment. The researchers want to compare two approaches: one...

Ga-68 Prostate Specific Membrane Antigen PET/CT in Gliomas

NCT ID: NCT06241391

This clinical trial is studying a new imaging technique called Ga-68 Prostate Specific Membrane Antigen (PSMA) PET/CT to see how well it can detect recurrent gliomas, which are types of brain tumor...

89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors

NCT ID: NCT05563272

This clinical trial is studying a special imaging technique using a substance called 89Zr-girentuximab to help doctors see certain types of solid tumors more clearly. The goal is to find out how we...

The Effectiveness of HP and TMZ Synergism on Adult Recurrence GBM

NCT ID: NCT06218524

This clinical trial is studying a new approach to treat patients with recurrent Glioblastoma Multiforme (GBM), a type of aggressive brain cancer. Researchers want to find out if combining a medicat...

Vacuolar ATPase and Drug Resistance of High Grade Gliomas

NCT ID: NCT05328089

This clinical trial is exploring how a specific type of protein pump, called V-ATPase, relates to treatment resistance in glioblastoma multiforme (GBM), a challenging type of brain tumor. Researche...

Deuterium Metabolic Imaging to Assess Radiotherapy Changes in Glioblastoma Multiforme

NCT ID: NCT05908669

The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)

NCT ID: NCT06146725

The RESBIOP study is researching the best surgical approach for older patients (70 years and older) or those with limited health status who are diagnosed with high-grade gliomas, a type of aggressi...

The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)

NCT ID: NCT06146738

The PALSUR study is looking at the best treatment options for patients with high-grade gliomas, which are aggressive types of brain tumors. Specifically, it compares three approaches: palliative ca...

The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients.

NCT ID: NCT03861299

The SAFE-Trial is a clinical study comparing two types of brain surgery for patients with glioblastoma, a type of aggressive brain cancer. The study will involve 246 patients who have tumors locate...

PreOperative Brain Irradiation in Glioblastoma

NCT ID: NCT03582514

The PreOperative Brain Irradiation in Glioblastoma (POBIG) trial is a study designed to explore the safety and effectiveness of giving a single dose of radiation therapy before surgery in patients ...

New Antigens Against Glioblastoma

NCT ID: NCT05917821

This clinical trial is focused on developing new treatments for glioblastoma multiforme, a type of aggressive brain cancer. Researchers will be working on creating special proteins called monoclona...

131I-TLX-101 for Treatment of Newly Diagnosed Glioblastoma (IPAX-2)

NCT ID: NCT05450744

This clinical trial, called IPAX-2, is looking at a new treatment for patients with newly diagnosed glioblastoma, a type of aggressive brain tumor. The study will test a radioactive medication call...