Clinical Trials for Glioma, Malignant

Find clinical trials for glioma, malignant. Discover research opportunities and treatment options in your area.

32 Active Trials Found

Showing 32 trials on this page

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Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

NCT ID: NCT06810544

This clinical trial is looking at a new treatment called TNG456, which is being tested alone and together with another medication called abemaciclib for patients with advanced solid tumors that hav...

Recruiting

Phase: PHASE1 Type: interventional Locations: Columbus, Ohio, United States, Houston, Texas, United States +2 more

CUE-102 in Recurrent Glioblastoma

NCT ID: NCT06917885

This clinical trial is investigating a new experimental drug called CUE-102 for patients with recurrent glioblastoma, a type of aggressive brain tumor. The main goal of the study is to ensure that ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

NCT ID: NCT05226494

This clinical trial is studying a new treatment called fb-PMT for patients with recurrent glioblastoma, which is a very aggressive type of brain cancer. The goal of the trial is to determine the sa...

Recruiting

Phase: PHASE1 Type: interventional Locations: New Haven, Connecticut, United States

Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma

NCT ID: NCT06169280

This clinical trial is looking at a new treatment approach for patients who have recently been diagnosed with high-grade glioma, a type of aggressive brain tumor. The main goal is to see if giving ...

Not yet recruiting

Phase: PHASE1 Type: interventional

Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases

NCT ID: NCT05474573

This clinical trial is looking at a new method to help doctors remove brain tumors called gliomas and brain metastases, which are tumors that have spread to the brain from other parts of the body. ...

Recruiting

Phase: NA Type: interventional Locations: Moscow, , Russian Federation

Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma

NCT ID: NCT04547777

This clinical trial is studying a new treatment for patients with recurrent malignant glioma, a type of aggressive brain tumor. The researchers are testing two experimental drugs, D2C7-IT and 2141-...

Recruiting

Phase: PHASE1 Type: interventional Locations: Durham, North Carolina, United States

Imaging of Solid Tumors Using 18F-TRX

NCT ID: NCT06942104

This clinical trial is studying a new imaging agent called 18F-TRX to see how safe and effective it is for detecting tumors in patients with solid cancers. 18F-TRX is a special tracer used during P...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: San Francisco, California, United States, San Francisco, California, United States

Window of Opportunity Study of DSP-0390 in Gliomas

NCT ID: NCT06636162

The Window of Opportunity Study is a clinical trial investigating a new drug called DSP-0390 for patients with specific types of brain tumors known as gliomas, particularly those with a mutation in...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States, Saint Louis, Missouri, United States

Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas

NCT ID: NCT06323408

This clinical trial is focused on studying how well different treatments work for certain brain tumors, specifically in adolescents and young adults aged 15 to 39. These tumors include types known ...

Not yet recruiting

Type: observational

PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial

NCT ID: NCT06397560

The PrOton Pulsed reduCed dOse Rate Radiotherapy trial is studying a new type of radiation treatment called "PRDR radiotherapy." This trial is specifically looking at how well this treatment works ...

Not yet recruiting

Phase: NA Type: interventional Locations: Miami, Florida, United States, Boca Raton, Florida, United States

AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients

NCT ID: NCT05182905

This clinical trial is studying a new treatment called AZD1390 for patients with advanced brain tumors known as WHO Grade 4 gliomas, which include conditions like glioblastoma. The trial is open to...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Phoenix, Arizona, United States

An Integrated Radio-immunological Approach

NCT ID: NCT05267509

This clinical trial is studying a type of aggressive brain tumor called glioblastoma, which affects adults. The researchers want to understand how certain immune cells in the body, particularly tho...

Recruiting

Type: observational Locations: Florence, , Italy, Padova, , Italy

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

NCT ID: NCT05773326

This clinical trial is studying a treatment called temsirolimus for patients with recurrent high-grade gliomas, which are aggressive brain tumors. The trial aims to see how well temsirolimus works ...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Phoenix, Arizona, United States

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

NCT ID: NCT05555550

This clinical trial is exploring the use of a special imaging technique called 18F-Fluciclovine Positron Emission Tomography-Magnetic Resonance Imaging (PET-MRI) to help manage low-grade gliomas (L...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Philadelphia, Pennsylvania, United States

FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma

NCT ID: NCT06172595

This clinical trial is studying a special imaging test called O-(2-[18F]fluoroethyl)-L-tyrosine (FET) PET to help doctors tell the difference between two important conditions in patients with high-...

Recruiting

Phase: PHASE2 Type: interventional Locations: Singapore, , Singapore, Singapore, , Singapore

Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients with Grade 2 or 3 Diffuse Glioma

NCT ID: NCT06468176

This clinical trial is studying the effects of a special rehabilitation program designed to help patients with grade 2 or 3 diffuse glioma, which are types of brain tumors. These tumors often cause...

Recruiting

Phase: NA Type: interventional Locations: Nancy, , France, Amiens, , France +7 more

Clinical Study on the Safety and Efficacy of TS-2021 in the Treatment of Recurrent Malignant Glioma

NCT ID: NCT06585527

This clinical trial is studying a new treatment called TS-2021, which is an oncolytic virus designed to target and fight recurrent malignant gliomas, a type of brain tumor. The main goal is to see ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China

18F-Fluciclovine PET-MRI in High-grade Glioma

NCT ID: NCT05553041

This clinical trial is studying a special type of imaging called 18F-fluciclovine PET-MRI to see if it can help doctors better manage high-grade gliomas in children. High-grade gliomas are aggressi...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

NCT ID: NCT05271240

This clinical trial is looking at a new way to treat newly diagnosed glioblastoma (GBM), a type of aggressive brain cancer. Researchers want to see if a treatment called Superselective Intraarteria...

Recruiting

Phase: PHASE3 Type: interventional Locations: New York, New York, United States

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

NCT ID: NCT05954858

This clinical trial is looking at a new surgical technique for patients with a type of brain cancer called glioblastoma multiforme (GBM). The study aims to find out if using a special tissue flap d...

Recruiting

Phase: NA Type: interventional Locations: New York, New York, United States

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