Clinical Trials for Hairy Cell Leukemia

Find clinical trials for hairy cell leukemia. Discover research opportunities and treatment options in your area.

11 Active Trials Found

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Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant

NCT ID: NCT04815356

This clinical trial is investigating a new treatment for hairy cell leukemia (HCL) using a method called CAR T cell therapy. In this study, doctors will take a patient's immune cells, modify them i...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia

NCT ID: NCT00412594

This clinical trial is studying the combination of two treatments, cladribine and rituximab, to see how effective they are in treating patients with hairy cell leukemia, a type of blood cancer. Cla...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Study for Patients With Hairy Cell Leukemia to Test the Targeted Agent Tovorafenib in Combination With Rituximab and Compare the Combination With Current Standard Treatment

NCT ID: NCT06965114

This clinical trial is studying a new treatment for patients with hairy cell leukemia (HCL), a type of blood cancer. The researchers want to see if a combination of a drug called tovorafenib and an...

Not yet recruiting

Phase: PHASE1 Type: interventional

Binimetinib for People With Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant

NCT ID: NCT04322383

This clinical trial is studying a medication called binimetinib as a potential treatment for hairy cell leukemia in patients who do not have a specific gene mutation known as BRAF. Hairy cell leuke...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Encorafenib Plus Binimetinib for People With BRAF V600 Mutated Relapsed/Refractory HCL

NCT ID: NCT04324112

This clinical trial is studying whether a combination of two medications, encorafenib and binimetinib, is more effective than a single medication, vemurafenib, for treating adults with hairy cell l...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

NCT ID: NCT06340737

This clinical trial is studying a new treatment called CD22 CAR T-cell therapy for adults with certain types of blood cancers known as B cell lymphomas. These cancers include follicular lymphoma, m...

Recruiting

Phase: PHASE1 Type: interventional Locations: Palo Alto, California, United States

Assessment of Disease Burden in Hairy Cell Leukemia

NCT ID: NCT06781515

This clinical trial is looking at the impact of Hairy Cell Leukemia (HCL) on patients' lives and how the disease affects them over time. It’s a study where participants will not receive any new tre...

Recruiting

Phase: NA Type: interventional Locations: Bologna, , Italy

A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People with Hairy Cell Leukemia (HCL)

NCT ID: NCT06561360

This clinical trial is studying two different treatment combinations for people with Hairy Cell Leukemia (HCL). Researchers want to compare vemurafenib plus obinutuzumab with the standard treatment...

Recruiting

Phase: PHASE2 Type: interventional Locations: Columbus, Ohio, United States, Rochester, Minnesota, United States +8 more

Therapy Optimisation for the Treatment of Hairy Cell Leukemia

NCT ID: NCT02131753

This clinical trial is studying a new treatment approach for patients with hairy cell leukemia, a rare type of blood cancer. The researchers want to see how well a single cycle of cladribine, given...

Recruiting

Phase: PHASE2 Type: interventional Locations: Wiesbaden, , Germany, Frankfurt, , Germany +72 more

Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.

NCT ID: NCT04775745

This clinical trial is studying a new medication called LP-168, which is being tested for patients with certain types of blood cancers known as B-cell malignancies, including chronic lymphocytic le...

Recruiting

Phase: PHASE1 Type: interventional Locations: Columbus, Ohio, United States, Cincinnati, Ohio, United States +2 more

Assessing Medical Trial Experiences of Hairy Cell Leukemia Patients

NCT ID: NCT05859932

This clinical trial is focused on understanding the experiences of patients with hairy cell leukemia when it comes to participating in clinical studies. Specifically, it looks at why patients choos...

Not yet recruiting

Type: observational

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