Clinical Trials for Hepatocellular Cancer

Find clinical trials for hepatocellular cancer. Discover research opportunities and treatment options in your area.

21 Active Trials Found

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A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies

NCT ID: NCT06690281

This clinical trial is studying a new type of treatment called T-cell therapy for patients with advanced gastrointestinal (GI) cancers, such as pancreatic, liver, and colorectal cancers. The goal i...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

NCT ID: NCT06858813

This clinical trial is investigating a new treatment called ABBV-324 for adults with two types of cancer: hepatocellular cancer (HCC), which affects the liver, and squamous-cell non-small cell lung...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Juan, , Puerto Rico, Duarte, California, United States +9 more

HepQuant: Study to Assess the Role of Blood-based Biomarkers and Quantitative MR Imaging for Patients Receiving Radiation Therapy for Liver Cancer

NCT ID: NCT06899152

The HepQuant study is looking at new ways to measure liver function in patients with liver cancer who are receiving radiation therapy. The researchers want to see if a special type of MRI, which ca...

Recruiting

Phase: NA Type: interventional Locations: Bronx, New York, United States

Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED)

NCT ID: NCT05451043

This clinical trial is investigating a new treatment approach for patients with advanced cancers of the pancreas, liver, and bile ducts. It combines two immunotherapy drugs, Durvalumab and Tremelim...

Recruiting

Phase: PHASE2 Type: interventional Locations: Edmonton, Alberta, Canada

ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk

NCT ID: NCT05064553

The ALTUS clinical trial is studying a new test called Oncoguard™ Liver, which aims to detect hepatocellular carcinoma (HCC), a type of liver cancer, in people who are at higher risk. This trial is...

Recruiting

Type: observational Locations: Ann Arbor, Michigan, United States, Philadelphia, Pennsylvania, United States +76 more

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

NCT ID: NCT06239194

This clinical trial is testing a new treatment called MDX2001 for patients with advanced solid tumors, which are cancers that form in organs or tissues, such as breast, lung, or colorectal cancer. ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Nashville, Tennessee, United States +4 more

GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Hepatocellular Carcinoma (HCC)

NCT ID: NCT05003895

This clinical trial is exploring a new treatment for advanced liver cancer, specifically a type called hepatocellular carcinoma (HCC) that expresses a protein known as Glypican-3 (GPC3). The treatm...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

A Longitudinal Observational Study of the Natural History and Management of Patients With HCC

NCT ID: NCT02954094

The TARGET-HCC study is a research project that focuses on understanding how patients with hepatocellular cancer (HCC) are treated and managed in real-life situations. This study aims to collect in...

Recruiting

Type: observational Locations: Rochester, Minnesota, United States, Ann Arbor, Michigan, United States +75 more

A Study of SHR-1826 Monotherapy or in Combination With Immunotherapy in the Treatment of Advanced Hepatocellular Cancer

NCT ID: NCT06935175

This clinical trial is studying a new treatment called SHR-1826, either on its own or combined with immunotherapy, for people with advanced hepatocellular cancer, which is a type of liver cancer. T...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Shanghai, , China

Atezolizumab Plus Bevacizumab Alone or Combined with External Beam Radiotherapy for HCC with Macrovascular Invasion

NCT ID: NCT05992220

This clinical trial is studying a combination treatment for patients with advanced liver cancer, specifically Hepatocellular Carcinoma (HCC) that has spread into the blood vessels within the liver....

Recruiting

Phase: PHASE2 Type: interventional Locations: Seoul, , Korea, Republic Of, Seoul, , Korea, Republic Of +1 more

A Study of Oral 7HP349 (Alintegimod) in Combination with Ipilimumab Followed by Nivolumab Monotherapy

NCT ID: NCT06362369

This clinical trial is testing a new medication called Alintegimod, taken by mouth, in combination with two other treatments for patients with advanced cancers, such as melanoma, kidney cancer, and...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Lebanon, New Hampshire, United States +1 more

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

NCT ID: NCT02838836

This clinical trial is investigating how tumor cells and DNA can be detected in the blood, urine, and bone marrow of patients with solid tumors, such as lung, esophageal, gastric, pancreatic, liver...

Recruiting

Type: observational Locations: Columbia, Missouri, United States

Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

NCT ID: NCT03551951

This clinical trial is investigating how to detect cancer cells and pieces of DNA from tumors in the blood, urine, and bone marrow of patients with certain types of solid cancers, like lung, esopha...

Recruiting

Type: observational Locations: Columbia, Missouri, United States

SIRT With Tremelimumab and Durvalumab for Resectable HCC

NCT ID: NCT05701488

This clinical trial is exploring a new treatment approach for patients with resectable hepatocellular carcinoma (HCC), a type of liver cancer that can be surgically removed. The study is investigat...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor Q702 in Combination With Pembrolizumab in Patients With Selected Advanced Solid Tumors

NCT ID: NCT05438420

This clinical trial is investigating a new treatment combination for patients with advanced cancers, specifically esophageal, gastric, liver, and cervical cancers. The study is testing a medication...

Recruiting

Phase: PHASE1 Type: interventional Locations: Los Angeles, California, United States, Louisville, Kentucky, United States +6 more

Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC

NCT ID: NCT04912765

This clinical trial is studying a new treatment approach for patients with liver cancer, specifically hepatocellular carcinoma (HCC) or colorectal cancer that has spread to the liver. The researche...

Recruiting

Phase: PHASE2 Type: interventional Locations: Singapore, , Singapore

Volatile Organic Compounds for the Assessment of Liver Disease

NCT ID: NCT04620538

This clinical trial is studying whether a simple breath test can help detect liver diseases like fibrosis, cirrhosis, or liver cancer (hepatocellular carcinoma) at an early stage. Researchers belie...

Recruiting

Type: observational Locations: London, , United Kingdom

High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors

NCT ID: NCT04033107

This clinical trial is investigating the use of high-dose vitamin C combined with metformin, a medication commonly used for diabetes, to see if it can help treat certain types of advanced cancers, ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Wuhan, Hubei, China

Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria

NCT ID: NCT05185505

The clinical trial is investigating the use of two medications, atezolizumab and bevacizumab, for patients with a type of liver cancer called hepatocellular carcinoma (HCC) who do not meet certain ...

Recruiting

Phase: PHASE4 Type: interventional Locations: Houston, Texas, United States

Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients

NCT ID: NCT03787056

This clinical trial is studying a substance called progastrin, which is usually not found in healthy people's blood but can be released in higher amounts in patients with various types of cancer. R...

Recruiting

Phase: NA Type: interventional Locations: Bron, , France, Lyon, , France +15 more

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