Clinical Trials for HPV Positive Oropharyngeal Squamous Cell Carcinoma

Find clinical trials for hpv positive oropharyngeal squamous cell carcinoma. Discover research opportunities and treatment options in your area.

17 Active Trials Found

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A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

NCT ID: NCT06319963

This clinical trial is testing a new treatment called Lenti-HPV-07 for patients with cervical or oropharyngeal cancer caused by the Human Papilloma Virus (HPV). The main goals are to find out if Le...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tampa, Florida, United States, Tampa, Florida, United States +2 more

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

NCT ID: NCT06790966

This clinical trial is studying a new treatment combination for patients with recurrent or metastatic head and neck cancer that tests positive for a specific virus called HPV16. The trial is compar...

Recruiting

Phase: PHASE3 Type: interventional Locations: Rochester, Minnesota, United States, Baltimore, Maryland, United States +5 more

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

NCT ID: NCT05814549

This clinical trial is studying a new blood test called NavDx® to see if it can help detect oropharyngeal cancer (a type of throat cancer) that is linked to the Human Papillomavirus (HPV). The rese...

Recruiting

Type: observational Locations: New York, New York, United States, Basking Ridge, New Jersey, United States +5 more

A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

NCT ID: NCT05307939

This clinical trial is investigating whether measuring levels of cell-free tumor DNA (ctDNA) from the human papillomavirus (HPV) can help doctors decide when to start routine treatments for patient...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Basking Ridge, New Jersey, United States +5 more

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

NCT ID: NCT06088381

The SAVAL clinical trial is studying a new way to help patients with HPV-related oropharyngeal cancer, which is a type of head and neck cancer. The main goal of this study is to see if a special bl...

Recruiting

Phase: PHASE2 Type: interventional Locations: Baltimore, Maryland, United States, Glen Burnie, Maryland, United States +4 more

De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE)

NCT ID: NCT06307015

The DE-RADIATE trial is a study focusing on a specific type of throat cancer known as HPV-positive oropharyngeal squamous cell carcinoma. The main goal of the trial is to find out if patients with ...

Not yet recruiting

Phase: NA Type: interventional Locations: Saint Leonards, New South Wales, Australia

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

NCT ID: NCT05973487

This clinical trial is studying a new treatment called TCR-T cell therapy for patients with advanced forms of certain types of cancer, including head and neck cancer, cervical cancer, and melanoma,...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Chicago, Illinois, United States +18 more

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

NCT ID: NCT05686226

This clinical trial is exploring a new type of immunotherapy called E7 TCR-T cell therapy for patients with certain cancers linked to the human papillomavirus (HPV), such as cervical, throat, and a...

Recruiting

Phase: PHASE2 Type: interventional Locations: New Brunswick, New Jersey, United States, New Brunswick, New Jersey, United States +1 more

Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal Carcinoma

NCT ID: NCT03215719

This clinical trial is investigating a new approach to treating a specific type of throat cancer called HPV-positive oropharyngeal carcinoma. Researchers want to see if they can safely reduce the a...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

NCT ID: NCT05639972

This clinical trial is exploring a new treatment called E7 T-cell receptor (TCR) T-cell therapy for patients with advanced cancers linked to the human papillomavirus (HPV), such as cervical and thr...

Recruiting

Phase: PHASE1 Type: interventional Locations: New Brunswick, New Jersey, United States, New Brunswick, New Jersey, United States +1 more

De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx

NCT ID: NCT05600842

This clinical trial is studying the effects of giving a lower dose of radiation to patients with HPV-positive oropharyngeal cancer, which is a type of throat cancer linked to the human papillomavir...

Recruiting

Type: observational Locations: Orange, California, United States

A Phase I/IIa Clinical Trial to Investigate BVAC-E6E7 in Subjects with HPV Positive HNSCC.

NCT ID: NCT06797986

This clinical trial is examining a new immunotherapy vaccine called BVAC-E6E7, specifically designed to treat certain types of advanced head and neck cancers that are associated with human papillom...

Not yet recruiting

Phase: PHASE1 Type: interventional

Safety and Efficacy of VB10.16 and Pembrolizumab in Patients with Head-Neck Squamous Cell Carcinoma

NCT ID: NCT06016920

This clinical trial is investigating a new treatment for patients with a specific type of head and neck cancer known as HPV16-positive oropharyngeal squamous cell carcinoma, which is often difficul...

Recruiting

Phase: PHASE1 Type: interventional Locations: Lyon, , France, Oslo, , Norway +15 more

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

NCT ID: NCT05108870

This clinical trial is testing a new treatment approach for patients with HPV-positive head and neck cancers, specifically oropharyngeal squamous cell carcinoma. The researchers want to see if comb...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States

Surgery and Reducing Ionizing Radiation of the Unknown Primary

NCT ID: NCT06578871

The SUPERIOR trial is studying the best ways to treat certain types of head and neck cancer, particularly when doctors can't find the original tumor but see cancer in the lymph nodes. This often ha...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Adelaide, South Australia, Australia, Adelaide, South Australia, Australia +3 more

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

NCT ID: NCT04900623

The ReACT Study is a clinical trial aimed at finding the best treatment approach for patients with HPV-related oropharyngeal cancer, which is a type of throat cancer linked to the human papillomavi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +1 more

Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer

NCT ID: NCT04444869

This clinical trial is looking at a new way to treat patients with HPV-positive oropharyngeal cancer, which is a type of throat cancer. The researchers want to see if giving a standard dose of chem...

Recruiting

Phase: PHASE2 Type: interventional Locations: Columbia, Missouri, United States

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