Vaccine Responses in Patients With B Cell Malignancies

NCT ID: NCT05170399

This clinical trial is looking at how well vaccines work for patients with certain types of blood cancers known as B cell malignancies, such as chronic lymphocytic leukemia (CLL) and lymphoma. Many...

Recruiting

Phase: PHASE4 Type: interventional Locations: Bethesda, Maryland, United States

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

NCT ID: NCT01441089

This clinical trial is studying how certain genes may affect the way people with cancer respond to treatment. Researchers believe that some genes can influence the side effects of treatment and how...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

NCT ID: NCT06856226

This clinical trial is studying how our genes affect how medications are processed in patients who receive a special treatment called allogeneic hematopoietic stem cell transplant (HSCT). After thi...

Not yet recruiting

Type: observational Locations: Bethesda, Maryland, United States

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

NCT ID: NCT06084936

This clinical trial is investigating a new treatment called glofitamab for patients with relapsed or refractory mantle cell lymphoma (MCL), which means their cancer has come back or hasn't responde...

Recruiting

Phase: PHASE3 Type: interventional Locations: Paris, France, Sioux Falls, South Dakota, United States +120 more

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma

NCT ID: NCT04739813

This clinical trial, called ViPOR-P, is exploring a new combination of medications to help adults with certain types of B-cell lymphoma, which is a kind of blood cancer. Specifically, the researche...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype

NCT ID: NCT06522737

This clinical trial is studying a new treatment called duvelisib for patients with a type of lymphoma known as nodal T cell lymphoma, specifically those with a T Follicular Helper (TFH) phenotype. ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Nottingham, United Kingdom, Caen, France +18 more

Value of Super-resolution Ultrasonography in Differentiating Benign and Malignant Lymph Nodes

NCT ID: NCT07155954

This clinical trial is studying a new ultrasound technique called super-resolution ultrasound (SRUS) to see if it can better tell the difference between harmless (benign) and harmful (malignant) sw...

Recruiting

Type: observational

Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

NCT ID: NCT03258567

This clinical trial is studying a drug called Nivolumab to see if it can help slow down or stop the growth of certain cancers related to the Epstein-Barr Virus (EBV), specifically EBV-positive lymp...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

NCT ID: NCT05237986

This clinical trial is looking at how CAR T-cell therapy, a new treatment for blood cancers like leukemia and lymphoma, may affect thinking and memory in children and young adults between the ages ...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, Los Angeles, California, United States +2 more

GSL Synthetase Inhibitor Eliglustat Combined With CD30 Target Immunotherapy for the Treatment of of CD30+ Lymphoma

NCT ID: NCT07138547

This clinical trial is studying a new treatment approach for a type of cancer called CD30-positive lymphoma, which means the cancer cells have a specific marker called CD30. The study is testing wh...

Not yet recruiting

Phase: PHASE1 Type: interventional

Neuromodulation of Cardiovascular Risks Associated With Cardiotoxic Chemotherapy

NCT ID: NCT05921253

This clinical trial is exploring whether a treatment called low-level vagus nerve stimulation can help improve heart health in people with breast cancer or lymphoma who have recently received certa...

Recruiting

Phase: NA Type: interventional Locations: Oklahoma City, Oklahoma, United States, Tulsa, Oklahoma, United States

A Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma

NCT ID: NCT07030699

This clinical trial is studying a new combination of medicines—epcoritamab, tafasitamab, and lenalidomide—to treat people with a type of blood cancer called diffuse large B-cell lymphoma (DLBCL) th...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Harrison, New York, United States +5 more

Mosunetuzumab for CLL MRD Clearance

NCT ID: NCT07052695

This clinical trial is studying a new treatment called mosunetuzumab, either by itself or combined with drugs known as BTK inhibitors, for people with chronic lymphocytic leukemia (CLL) or small ly...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Odronextamab in Low Tumor Volume Advanced FL

NCT ID: NCT07128641

This clinical trial is studying a new treatment called odronextamab for people who have been newly diagnosed with follicular lymphoma, a type of slow-growing blood cancer that affects the lymph nod...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States

A Study of Mosunetuzumab Alone or With Zanubrutinib in People With Follicular Lymphoma

NCT ID: NCT05389293

This clinical trial is studying a new treatment called mosunetuzumab for people with follicular lymphoma, a type of cancer that affects the lymphatic system, and who have recently been diagnosed bu...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Middletown, New Jersey, United States +8 more

Rituximab Plus Venetoclax in Front Line Marginal Zone Lymphoma

NCT ID: NCT06510309

This clinical trial is looking at whether a combination of two medications, rituximab and venetoclax, can effectively treat people with untreated Marginal Zone Lymphoma (MZL), a type of cancer. The...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States

Epcoritamab in Patients With Follicular Lymphoma Not Accomplishing a CR With Upfront Chemoimmunotherapy

NCT ID: NCT06510361

This clinical trial is studying a new treatment called epcoritamab for patients with follicular lymphoma who did not achieve complete remission after their initial chemotherapy and antibody treatme...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States

A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma

NCT ID: NCT03829254

This clinical trial is studying a new treatment called NUC-7738 for patients with advanced cancers, including solid tumors and lymphoma. The trial is divided into two phases. In the first phase, re...

Recruiting

Phase: PHASE1 Type: interventional Locations: London, United Kingdom, Newcastle, United Kingdom +9 more

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

NCT ID: NCT04570423

This clinical trial is studying a medication called eflapegrastim to see how safe it is and how it works in children who have solid tumors or lymphomas and are receiving chemotherapy that can lower...

Recruiting

Phase: PHASE2 Type: interventional Locations: Valhalla, New York, United States, Houston, Texas, United States +2 more

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

NCT ID: NCT03226704

This study is not testing a new drug right away. It’s an observational program intended to identify people who might benefit from future CAR-T cell therapy and to collect and store a sample of thei...

Enrolling by invitation

Type: observational Locations: Bethesda, Maryland, United States

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Clinical Trials for Lymphoma

235 Active Trials Found

Vaccine Responses in Patients With B Cell Malignancies

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma

A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype

Value of Super-resolution Ultrasonography in Differentiating Benign and Malignant Lymph Nodes

Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

GSL Synthetase Inhibitor Eliglustat Combined With CD30 Target Immunotherapy for the Treatment of of CD30+ Lymphoma

Neuromodulation of Cardiovascular Risks Associated With Cardiotoxic Chemotherapy

A Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma

Mosunetuzumab for CLL MRD Clearance

Odronextamab in Low Tumor Volume Advanced FL

A Study of Mosunetuzumab Alone or With Zanubrutinib in People With Follicular Lymphoma

Rituximab Plus Venetoclax in Front Line Marginal Zone Lymphoma

Epcoritamab in Patients With Follicular Lymphoma Not Accomplishing a CR With Upfront Chemoimmunotherapy

A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

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