Clinical Trials for Malaria,Falciparum

Find clinical trials for malaria,falciparum. Discover research opportunities and treatment options in your area.

13 Active Trials Found

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A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™

NCT ID: NCT06320535

This clinical trial is studying a new malaria vaccine called R21/Matrix-M™ to see how safe it is and how well it can help the body build protection against malaria. The trial is focused on healthy ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bristol, , United Kingdom, Oxford, Oxfordshire, United Kingdom

An Observational Study to Assess Effectiveness and Safety of The R21/Matrix-M Malaria Vaccine

NCT ID: NCT07009847

This clinical trial is studying the R21/Matrix-M malaria vaccine to see how effective it is in preventing severe malaria and clinical malaria, especially in areas where malaria is common. The resea...

Not yet recruiting

Type: observational Locations: Boussé, , Burkina Faso, Toumodi, , Côte D'ivoire +3 more

Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV371 LAI in Healthy Participants

NCT ID: NCT06558643

This clinical trial is testing a new medication called MMV371 LAI to see how safe it is and how well it is absorbed by the body when given as a single injection. The study involves healthy adults a...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ruddington, Nottingham, United Kingdom

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics

NCT ID: NCT05757167

The INTREPiD study is a clinical trial aimed at improving the health of newborns by testing pregnant women for malaria early in their pregnancy. Researchers want to see if using a special, highly s...

Recruiting

Phase: PHASE4 Type: interventional Locations: Kinshasa, , Congo, The Democratic Republic Of The, Eldoret, , Kenya

A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria Vaccine)

NCT ID: NCT06958198

This clinical trial is studying a new malaria vaccine called R21, which is combined with two other vaccines, RH5.1 and R78C, to see how safe it is and how well it works in generating an immune resp...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Sigle,, , Burkina Faso, Sigle,, , Burkina Faso

A Study to Test Experimental Blood Stage Malaria Vaccine in Burkina Faso.

NCT ID: NCT05790889

This clinical trial is studying a new malaria vaccine designed for infants aged 5 to 17 months in Burkina Faso. The goal is to see how safe and effective this vaccine is in protecting young childre...

Recruiting

Phase: PHASE1 Type: interventional Locations: Sigle, , Burkina Faso, Sigle, , Burkina Faso

Durability of Protection After Single Immunisation With GA2 Sporozoites (CoGA-Rechallenge)

NCT ID: NCT06293339

This clinical trial, called CoGA-Rechallenge, is looking at how long protection lasts after a single immunization with a specially modified malaria parasite called GA2. The goal is to see if people...

Not yet recruiting

Phase: PHASE1 Type: interventional

Preventing Malaria in School Children to Protect the Whole Community in Rural Blantyre District, Malawi

NCT ID: NCT06083688

This clinical trial is focused on preventing malaria, a serious disease, among school children in rural Blantyre District, Malawi. The study is testing different medications to see which one works ...

Recruiting

Phase: PHASE4 Type: interventional Locations: Blantyre, , Malawi

Safety and Immunogenicity of SUM-101 Malaria Vaccine in Children and Infants Living in Burkina Faso

NCT ID: NCT06618885

This clinical trial is studying the safety and effectiveness of a new malaria vaccine called SUM-101 in young children and infants living in Burkina Faso. The researchers want to find out if the va...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Ouagadougou, , Burkina Faso

The Impact RTS,S/AS01 Vaccine in School Aged Children RTS,S/AS01 Malaria Vaccine in School Aged Children

NCT ID: NCT06424002

This clinical trial is studying the RTS,S/AS01 malaria vaccine to see how well it works in school-aged children, specifically those between 6 and 15 years old. Malaria is a serious disease that aff...

Not yet recruiting

Phase: PHASE4 Type: interventional

Seasonal Malaria Chemoprevention Rapid Assessment Study Mozambique

NCT ID: NCT06337253

The Seasonal Malaria Chemoprevention Rapid Assessment Study in Mozambique is looking at a way to prevent malaria, specifically the type caused by Plasmodium falciparum, which is common in areas whe...

Not yet recruiting

Phase: PHASE4 Type: interventional

Addressing Asymptomatic Plasmodium Reservoirs to Accelerate Malaria Elimination and Eradication in Rwanda.

NCT ID: NCT05801198

This clinical trial is focused on finding new ways to eliminate malaria in Rwanda by targeting people who have the malaria parasite but do not show symptoms, known as asymptomatic reservoirs. Resea...

Not yet recruiting

Phase: PHASE2 Type: interventional

Effect of Paracetamol on Kidney Function in Severe Malaria

NCT ID: NCT04251351

This clinical trial is investigating whether paracetamol can help protect the kidneys of children suffering from severe malaria. Severe malaria can cause serious complications, including damage to ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Kinshasa, Congo, Congo, The Democratic Republic Of The

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