Clinical Trials for Mantle Cell Lymphoma

Find clinical trials for mantle cell lymphoma. Discover research opportunities and treatment options in your area.

79 Active Trials Found

Showing 79 trials on this page

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A Long-term Extension Study of PCI-32765 (Ibrutinib)

NCT ID: NCT01804686

This clinical trial is focused on studying the long-term safety and effectiveness of a medication called ibrutinib for patients with various types of blood cancers, including chronic lymphocytic le...

Recruiting

Phase: PHASE3 Type: interventional Locations: Lebanon, New Hampshire, United States, Charlottesville, Virginia, United States +203 more

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

NCT ID: NCT04195633

This clinical trial is studying a new treatment approach for patients with various types of blood cancers, such as acute leukemia and lymphoma. The treatment combines a donor stem cell transplant w...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma

NCT ID: NCT06742996

This clinical trial is studying a new combination treatment for adults with a type of cancer called mantle cell lymphoma (MCL) that has come back or has not responded to previous treatments. The re...

Recruiting

Phase: PHASE3 Type: interventional Locations: Ann Arbor, Michigan, United States, Rochester, Minnesota, United States +209 more

A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)

NCT ID: NCT05458297

This clinical trial is studying a new treatment called zilovertamab vedotin for patients with certain types of B-cell lymphomas, including chronic lymphocytic leukemia (CLL), mantle cell lymphoma (...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seoul, , Korea, Republic Of, Warszawa, Mazowieckie, Poland +159 more

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

NCT ID: NCT05724121

This clinical trial is studying how certain cancer treatments, specifically Bruton’s tyrosine kinase inhibitors (BTKi) and venetoclax, affect heart health. These medications are often used for cond...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

NCT ID: NCT05976763

This clinical trial is studying the best way to use the drug zanubrutinib for older patients with mantle cell lymphoma (MCL) who have not been treated before. Specifically, researchers want to find...

Recruiting

Phase: PHASE3 Type: interventional Locations: New Haven, Connecticut, United States, Durham, North Carolina, United States +231 more

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT ID: NCT05006716

This clinical trial is studying a new treatment called BGB-16673 for patients with specific types of B-cell cancers, such as Marginal Zone Lymphoma, Follicular Lymphoma, and Chronic Lymphocytic Leu...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Rochester, Minnesota, United States +197 more

SynKIR-310 for Relapsed/Refractory B-NHL

NCT ID: NCT06544265

The SynKIR-310 trial is a research study aimed at evaluating a new treatment called SynKIR-310 for adults with certain types of B-cell lymphoma that have not responded to previous therapies or have...

Recruiting

Phase: PHASE1 Type: interventional Locations: Fairway, Kansas, United States, Portland, Oregon, United States +1 more

A Study of Glofitamab and Lenalidomide in People With Mantle Cell Lymphoma

NCT ID: NCT06192888

This clinical trial is investigating the use of two medications, glofitamab and lenalidomide, to see if they can effectively treat people with Mantle Cell Lymphoma (MCL) who have not responded to p...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Middletown, New Jersey, United States +9 more

Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma

NCT ID: NCT06839053

This clinical trial is looking at a new treatment approach for patients with certain types of blood cancers, including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and mant...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States

Phase II Study of Pirtobrutinib, Rituximab (PR) in Previously Untreated Low and Intermediate Risk MCL (Mantle Cell Lymphoma) Patients

NCT ID: NCT06263491

This clinical trial is studying a combination of two medications, pirtobrutinib (also known as LOXO-305) and rituximab, to see if they can help patients with mantle cell lymphoma (MCL) who have not...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States, Houston, Texas, United States

GATE1: A Multicenter Phase II Study of Pirtobrutinib, Rituximab and Venetoclax Combination Therapy for Patients With Previously Untreated Mantle Cell Lymphoma

NCT ID: NCT06522386

The GATE1 clinical trial is studying a new treatment combination for patients with previously untreated mantle cell lymphoma (MCL), a type of blood cancer. The researchers want to see how effective...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

NCT ID: NCT06533579

This clinical trial is studying a new treatment called VNX-101 for patients with a type of blood cancer known as B-cell acute lymphoblastic leukemia (ALL) that has not responded to previous therapi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Valhalla, New York, United States, Duarte, California, United States +5 more

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

NCT ID: NCT05529069

This clinical trial is studying the combination of two medications, pirtobrutinib and venetoclax, to see if they can help control mantle cell lymphoma (MCL) in patients whose cancer has come back o...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Phase 2 Open Label Randomized Study of Pirtobrutinib and Brexucabtagene Autoleucel in R/R MCL

NCT ID: NCT06553872

This clinical trial is studying the combination of two treatments, Pirtobrutinib and Brexucabtagene Autoleucel (also called brexu-cel), for patients with relapsed or refractory mantle cell lymphoma...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States, Stanford, California, United States +1 more

CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies

NCT ID: NCT06208735

This clinical trial, called CLIC-2201, is exploring a new treatment for patients with certain types of B-cell cancers, such as B-cell leukemia and non-Hodgkin's lymphoma, that have either come back...

Recruiting

Phase: PHASE1 Type: interventional Locations: Calgary, Alberta, Canada, Vancouver, British Columbia, Canada +7 more

Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

NCT ID: NCT06252675

This clinical trial is studying a new treatment combination for patients with mantle cell lymphoma (MCL), a type of blood cancer that has either come back after treatment or has not responded to pr...

Recruiting

Phase: PHASE2 Type: interventional Locations: San Francisco, California, United States

AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

NCT ID: NCT06340737

This clinical trial is studying a new treatment called CD22 CAR T-cell therapy for adults with certain types of blood cancers known as B cell lymphomas. These cancers include follicular lymphoma, m...

Recruiting

Phase: PHASE1 Type: interventional Locations: Palo Alto, California, United States

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

NCT ID: NCT05602363

This clinical trial is studying a new oral medication called AS-1763 (docirbrutinib) for patients with certain types of blood cancers, including chronic lymphocytic leukemia (CLL), small lymphocyti...

Recruiting

Phase: PHASE1 Type: interventional Locations: Worcester, Massachusetts, United States, Miami Beach, Florida, United States +12 more

Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant

NCT ID: NCT03622788

This clinical trial is exploring a new treatment approach using special cells, called cytokine-treated veto cells, for patients with certain blood cancers after they have undergone a stem cell tran...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

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