Clinical Trials for Melanoma Stage III

Find clinical trials for melanoma stage iii. Discover research opportunities and treatment options in your area.

27 Active Trials Found

Showing 27 trials on this page

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IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients

NCT ID: NCT04562129

This clinical trial is exploring a new treatment approach for patients with advanced melanoma, specifically those in Stage III or IV who cannot have surgery. The study is testing whether giving a m...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States

Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma

NCT ID: NCT06295159

This clinical trial is studying a new type of treatment for patients with advanced melanoma, which is a serious skin cancer. The goal is to see if using immunotherapy—medications that help the body...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States

Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib Binimetinib in Melanoma

NCT ID: NCT04741997

This clinical trial is studying a new treatment approach for patients with melanoma that has a specific genetic mutation called BRAFV600. The goal is to see how well patients respond to a combinati...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Tampa, Florida, United States

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT05970497

This clinical trial is studying a new treatment called KB707 for adults with certain types of cancer, specifically those whose cancer has either spread or is difficult to treat with standard therap...

Recruiting

Phase: PHASE1 Type: interventional Locations: Nashville, Tennessee, United States, Cincinnati, Ohio, United States +15 more

Assessment of PK Similarity of FYB206 in Comparison With Keytruda in Resected Stage II or III Melanoma Patients

NCT ID: NCT06551064

This clinical trial is studying a new treatment called FYB206, which is designed to be similar to an existing cancer therapy known as Keytruda. Both treatments aim to help the immune system recogni...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chisinau, , Moldova, Republic Of, Kyiv, , Ukraine +7 more

CD8+ T Cell Imaging During Pre-surgery Immunotherapy in People With Melanoma

NCT ID: NCT05289193

This clinical trial is studying how a combination of two immunotherapy drugs, nivolumab and ipilimumab, can help shrink melanoma tumors before surgery. By using this treatment, researchers hope to ...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Basking Ridge, New Jersey, United States +2 more

Correlating Early FDG PET/CT and ctDNA in Immune Checkpoint Inhibitor (ICI)-Treated Melanoma Patients

NCT ID: NCT06199713

This clinical trial is looking at how certain tests can help doctors understand how well melanoma patients might respond to a type of treatment called immunotherapy. Specifically, researchers want ...

Recruiting

Type: observational Locations: Madison, Wisconsin, United States

SCIB1 and iSCIB1+ in Melanoma Patients Receiving Nivolumab With Ipilimumab or SCIB1 With Pembrolizumab (The SCOPE Study)

NCT ID: NCT04079166

The SCOPE Study is a clinical trial aimed at understanding if two experimental cancer vaccines, SCIB1 and iSCIB1+, can be safely combined with existing melanoma treatments, nivolumab (Opdivo) with ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Leeds, , United Kingdom, Manchester, , United Kingdom +14 more

To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma

NCT ID: NCT06204991

This clinical trial is investigating a new treatment called ADP-TILIL7 for patients with advanced melanoma, specifically those whose cancer cannot be surgically removed or has spread to other parts...

Not yet recruiting

Phase: PHASE1 Type: interventional

FMT to Convert Response to Immunotherapy

NCT ID: NCT05251389

This clinical trial is investigating whether fecal microbiota transplantation (FMT) can help patients with advanced melanoma who have not responded to standard immunotherapy treatments. The study w...

Recruiting

Phase: PHASE1 Type: interventional Locations: Amsterdam, , Netherlands

Safe Stop Ipilimumab-nivolumab (IPI-NIVO) Trial

NCT ID: NCT05652673

The Safe Stop Ipilimumab-Nivolumab (IPI-NIVO) Trial is investigating whether patients with advanced melanoma, specifically stage III or IV, can safely stop taking the drug nivolumab after showing a...

Recruiting

Phase: NA Type: interventional Locations: Rotterdam, , Netherlands

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

NCT ID: NCT05655312

This clinical trial is studying a new treatment called \[212Pb\]VMT01, which uses alpha particles to target a specific receptor (MC1R) in melanoma cells. The trial aims to find out how safe and eff...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, Madison, Wisconsin, United States +11 more

Clinical and Ultrasound Incidence of Rheumatologic Immune Related Adverse Events in Stage IIB-IV Melanoma Patients

NCT ID: NCT06780397

This clinical trial is looking at how often certain joint and muscle problems, known as rheumatologic immune-related adverse events, occur in patients with advanced melanoma (a type of skin cancer)...

Not yet recruiting

Type: observational Locations: Roma, Lazio, Italy

Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma

NCT ID: NCT06771544

This clinical trial is studying a combination of two medications, Cyclophosphamide and Pembrolizumab, to see how effective they are in treating patients with advanced melanoma, which is a type of s...

Recruiting

Phase: PHASE2 Type: interventional Locations: Orange, California, United States

Versatile Ampification Single-Molecule Detection in Liquid Biopsy

NCT ID: NCT05940311

This clinical trial, called VerSiLiB, is studying a new way to detect very small amounts of proteins and genetic material in blood samples from patients with a specific type of skin cancer called m...

Recruiting

Type: observational Locations: Rome, , Italy

A Study of Neoadjuvant Therapy With BCD-217 (Nurulimab + Prolgolimab) in Patients With Resectable Stage III Skin Melanoma

NCT ID: NCT05751928

This clinical trial is looking at a new treatment called BCD-217, which combines two drugs, Nurulimab and Prolgolimab, for patients with stage III skin melanoma that can be surgically removed. The ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Nizhny Novgorod, , Russian Federation, Saransk, , Russian Federation +34 more

Neoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) Vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in Melanoma

NCT ID: NCT04139902

This clinical trial is designed to explore two different treatment options for patients with operable melanoma, a type of skin cancer. The study compares a single treatment called Dostarlimab (an i...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +3 more

Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination with Pembrolizumab, in Unresectable Melanoma Patients

NCT ID: NCT06284590

This clinical trial is testing new treatments for patients with melanoma that cannot be surgically removed, specifically for those with advanced stages (Stage III or IV). The study is looking at th...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

NCT ID: NCT04598009

This clinical trial is studying the effectiveness of two medications, binimetinib and imatinib, for treating patients with advanced melanoma that has a specific genetic mutation (KIT-mutant melanom...

Recruiting

Phase: PHASE2 Type: interventional Locations: San Francisco, California, United States, La Jolla, California, United States

Long-Term Follow-up of Patients Treated With Miltenyi Cell and Gene Therapies

NCT ID: NCT06508775

This clinical trial is a long-term follow-up study for patients who have been treated with Miltenyi CAR T cell therapy for various types of cancer, including melanoma and different forms of leukemi...

Recruiting

Phase: NA Type: interventional Locations: Münster, , Germany, Göttingen, , Germany +2 more

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