Clinical Trials for Metastatic Lung Non-Small Cell Carcinoma

Find clinical trials for metastatic lung non-small cell carcinoma. Discover research opportunities and treatment options in your area.

27 Active Trials Found

Showing 27 trials on this page

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Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

NCT ID: NCT06500455

This clinical trial is studying a new type of radiation therapy called fractionated stereotactic radiosurgery (FSRS) to see if it works better than the usual radiation therapy (stereotactic radiosu...

Recruiting

Phase: PHASE3 Type: interventional Locations: Chicago, Illinois, United States, Cleveland, Ohio, United States +200 more

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

NCT ID: NCT06982222

This clinical trial is testing a new anti-cancer drug called Sn-117m-DTPA to see if it is safe and effective for patients with advanced cancers that have spread to the bones, such as prostate, brea...

Not yet recruiting

Phase: PHASE1 Type: interventional

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

NCT ID: NCT07012031

This clinical trial is studying the combination of two medications, sotorasib and trastuzumab deruxtecan, to see how safe and effective they are for treating patients with advanced non-small cell l...

Not yet recruiting

Phase: PHASE1 Type: interventional

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

NCT ID: NCT06910761

This clinical trial is exploring a new treatment method called photon craniospinal irradiation (CSI) for patients with leptomeningeal disease, which occurs when breast cancer or non-small cell lung...

Recruiting

Phase: PHASE2 Type: interventional Locations: Duarte, California, United States, Irvine, California, United States

Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer

NCT ID: NCT06249282

This clinical trial is studying the combination of two drugs, carfilzomib and sotorasib, to see if they can effectively treat patients with a specific type of advanced non-small cell lung cancer (N...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States, Irvine, California, United States

PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer

NCT ID: NCT04151940

The clinical trial titled "PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer" is studying how imaging tests, specifically PET and C...

Recruiting

Phase: NA Type: interventional Locations: Seattle, Washington, United States

Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent Immunotherapy

NCT ID: NCT06731270

This clinical trial is studying a medication called diclofenac to see if it can help patients with advanced non-small cell lung cancer (NSCLC) who are already receiving immunotherapy, a treatment t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Atlanta, Georgia, United States, Atlanta, Georgia, United States

GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer

NCT ID: NCT07017829

This clinical trial is studying a new treatment for patients with advanced or metastatic non-small cell lung cancer that has a specific genetic mutation called STK11. The researchers want to see if...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Buffalo, New York, United States

SX-682 With Pembrolizumab for the Treatment of Metastatic or Recurrent Stage IIIC or IV Non-Small Cell Lung Cancer

NCT ID: NCT05570825

This clinical trial is studying a combination of two medications, SX-682 and pembrolizumab, to see if they can effectively treat patients with advanced non-small cell lung cancer (NSCLC) that has s...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States

A Study of BDTX-4933 in Patients With KRAS, BRAF and Select RAS/MAPK Mutation-Positive Cancers

NCT ID: NCT05786924

This clinical trial is studying a new medication called BDTX-4933, which is being tested in patients with certain types of advanced cancers that have specific genetic mutations, like those found in...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States, New York, New York, United States +14 more

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

NCT ID: NCT06518057

This clinical trial is studying a new way to deliver radiation therapy called craniospinal irradiation (CSI) for patients with breast cancer or non-small cell lung cancer that has spread to the cer...

Recruiting

Phase: PHASE2 Type: interventional Locations: Seattle, Washington, United States

Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer

NCT ID: NCT06943664

This clinical trial is studying a new treatment approach for patients with advanced lung cancer called non-small cell lung cancer (NSCLC) that has not responded to previous therapies. The trial is ...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Buffalo, New York, United States

MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer

NCT ID: NCT04762199

This clinical trial is studying a new treatment approach for patients with advanced non-small cell lung cancer (NSCLC) that has a specific genetic mutation called EGFR. The trial is testing two med...

Recruiting

Phase: PHASE1 Type: interventional Locations: Atlanta, Georgia, United States

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

NCT ID: NCT03025256

This clinical trial is investigating a treatment for patients with leptomeningeal disease, which is a condition where cancer spreads to the membranes surrounding the brain and spinal cord. The stud...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

NCT ID: NCT04197934

This clinical trial is studying a new treatment called WSD0922-FU for patients with specific types of brain tumors, like glioblastoma and anaplastic astrocytoma, as well as non-small cell lung canc...

Recruiting

Phase: PHASE1 Type: interventional Locations: Scottsdale, Arizona, United States, Jacksonville, Florida, United States +1 more

PBF-1129 and Nivolumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

NCT ID: NCT05234307

This clinical trial is exploring a new treatment for patients with advanced non-small cell lung cancer (NSCLC) that has either returned after treatment or spread to other parts of the body. The stu...

Recruiting

Phase: PHASE1 Type: interventional Locations: Columbus, Ohio, United States

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

NCT ID: NCT05098210

This clinical trial is exploring a new treatment option called a personalized neo-antigen peptide vaccine for patients with advanced melanoma (a type of skin cancer) or hormone receptor-positive br...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

All-Trans Retinoic Acid (ATRA) and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

NCT ID: NCT04919369

This clinical trial is studying a combination of two treatments—all-trans retinoic acid (ATRA) and atezolizumab—for patients with non-small cell lung cancer that has either come back or spread to o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Columbus, Ohio, United States

Predicting Response to Immune Checkpoint Inhibitors Across Solid Tumors Using a Live Tumor Diagnostic Platform

NCT ID: NCT06349642

This clinical trial is investigating how well a new diagnostic tool called Elephas can predict how tumors respond to different cancer treatments, particularly immune therapies. The goal is to colle...

Recruiting

Type: observational Locations: Jacksonville, Florida, United States

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

NCT ID: NCT06500481

The RADIATE-LM trial is a clinical study that is comparing two types of radiation therapy for patients with certain types of advanced cancer, specifically breast cancer and non-small cell lung canc...

Recruiting

Phase: PHASE3 Type: interventional Locations: Little Rock, Arkansas, United States, New York, New York, United States +6 more

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