A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

NCT ID: NCT06803680

This clinical trial is studying a new treatment called BGB-B455 for adults with advanced or metastatic solid tumors, which are types of cancer that have spread and cannot be surgically removed. The...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States, Liverpool, New South Wales, Australia +19 more

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

NCT ID: NCT06108050

This clinical trial is studying a new treatment called JZP898, which is being given alone or alongside another medication called pembrolizumab to see how safe it is and how well it works for adults...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Nashville, Tennessee, United States +9 more

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

NCT ID: NCT06607185

This clinical trial is studying a new medication called LY4066434, which is designed to target specific mutations in a gene called KRAS found in certain types of cancer. The trial focuses on patien...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Durham, North Carolina, United States +73 more

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

NCT ID: NCT06238479

This clinical trial is investigating a new drug called LY4101174 to see if it is safe and effective for people with advanced solid tumors that have come back or spread to other parts of the body. T...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Boston, Massachusetts, United States +34 more

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

NCT ID: NCT06778863

This clinical trial is studying a new treatment called CLSP-1025 for adults with certain types of solid tumors that have a specific genetic mutation known as p53 R175H. These tumors can include adv...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hackensack, New Jersey, United States, New York, New York, United States +7 more

A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer

NCT ID: NCT06163391

This clinical trial is studying a new treatment called SOT201 for patients with advanced or metastatic solid tumors, which are cancers that have spread beyond their original site. The goal of the t...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Paris, , France +5 more

Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors

NCT ID: NCT06975410

This clinical trial is studying a new medication called YH32364 to see if it can help adults with advanced cancers that have a specific feature known as EGFR overexpression. This means the cancer c...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seoul, , Korea, Republic Of, Seoul, , Korea, Republic Of +2 more

A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

NCT ID: NCT06521554

The HEROEX-1 clinical trial is testing a new medication called NVL-330 in patients with advanced or metastatic non-small cell lung cancer (NSCLC) that have a specific change in the HER2 gene. This ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States +16 more

A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

NCT ID: NCT06952010

This clinical trial is studying a new treatment called XB628, which is being tested for people with advanced or spreading solid tumors that have come back after previous treatments. XB628 is a type...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Antonio, Texas, United States, Hickory, North Carolina, United States

A Study of CHS-114 in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

NCT ID: NCT06657144

This clinical trial is testing a new treatment called CHS-114, which is being studied in combination with another treatment called toripalimab, and possibly other standard therapies, for patients w...

Recruiting

Phase: PHASE1 Type: interventional Locations: Norfolk, Virginia, United States, Salt Lake City, Utah, United States +4 more

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT ID: NCT04585750

The PYNNACLE clinical trial is studying a new treatment called PC14586, aimed at patients with advanced solid tumors that have a specific genetic mutation known as TP53 Y220C. This trial is current...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Charleston, South Carolina, United States +90 more

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

NCT ID: NCT06440005

This clinical trial is studying a new treatment called AGX101, which is an antibody-drug conjugate designed for patients with advanced solid tumors, including types of cancer like triple-negative b...

Recruiting

Phase: PHASE1 Type: interventional Locations: Nashville, Tennessee, United States, San Antonio, Texas, United States +1 more

A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT ID: NCT06682806

This clinical trial is looking at a new treatment combination of PRT3789 and pembrolizumab for patients with advanced solid tumors that have a specific genetic change called a SMARCA4 mutation. The...

Recruiting

Phase: PHASE2 Type: interventional Locations: Hackensack, New Jersey, United States, Detroit, Michigan, United States +7 more

A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT ID: NCT06560645

This clinical trial is studying a new oral medication called PRT7732, which is designed to target a specific mutation (called SMARCA4) found in certain advanced or metastatic solid tumors, includin...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Houston, Texas, United States +22 more

Dose Escalation and Expansion Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid Tumors

NCT ID: NCT05479812

This clinical trial is studying a new treatment called WTX-124, which is being tested alone and in combination with another drug called pembrolizumab (often referred to as "Pembro"). The goal is to...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Hackensack, New Jersey, United States +9 more

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

NCT ID: NCT06561685

This clinical trial is studying a new medication called LY4050784 to see if it is safe and effective for people with advanced or metastatic solid tumors, particularly those with a specific genetic ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States +20 more

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

NCT ID: NCT06244771

This clinical trial is studying a new treatment called FMC-376 for patients with advanced solid tumors that have a specific genetic change known as the KRAS G12C mutation. These tumors can include ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Detroit, Michigan, United States +13 more

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

NCT ID: NCT06577987

This clinical trial is studying a new treatment called CID-078 for patients with advanced solid tumors, which are types of cancer that have spread and are not responding to standard treatments. The...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Nashville, Tennessee, United States +8 more

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

NCT ID: NCT05837767

This clinical trial is investigating a new type of radiation therapy called lattice radiation therapy (LRT) to see if it works better than the standard approach known as stereotactic body radiation...

Recruiting

Phase: NA Type: interventional Locations: New York, New York, United States, Harrison, New York, United States +5 more

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

NCT ID: NCT05856981

This clinical trial is testing a new treatment called ADU-1805 for patients with advanced solid tumors, which are types of cancers that are hard to treat with standard therapies. The main goal of t...

Recruiting

Phase: PHASE1 Type: interventional Locations: Detroit, Michigan, United States, Canton, Ohio, United States +7 more

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Clinical Trials for Metastatic Solid Tumor

60 Active Trials Found

A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer

Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors

A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

A Study of CHS-114 in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

Dose Escalation and Expansion Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid Tumors

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

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