Clinical Trials for Metastatic Solid Tumors

Find clinical trials for metastatic solid tumors. Discover research opportunities and treatment options in your area.

15 Active Trials Found

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A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT06031441

This clinical trial is studying a new medication called RO7566802, which is being tested alone and in combination with another drug called atezolizumab. The goal is to find out if these treatments ...

Recruiting

Phase: PHASE1 Type: interventional Locations: London, , United Kingdom, New Haven, Connecticut, United States +10 more

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

NCT ID: NCT06983743

This clinical trial is studying a new drug called ERAS-0015 to see if it is safe and tolerable for patients with advanced or metastatic solid tumors that have specific RAS mutations. The trial aims...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Fairfax, Virginia, United States +2 more

A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors

NCT ID: NCT06873789

This clinical trial is studying a new treatment called INCB177054, which may help people with advanced or metastatic solid tumors. The treatment will be tested on its own and in combination with an...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hackensack, New Jersey, United States, Los Angeles, California, United States +7 more

A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification

NCT ID: NCT06585488

This clinical trial is studying a new medication called BGB-53038, which is designed to target specific changes in cancer cells known as KRAS mutations. These changes can make certain types of canc...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seoul, , Korea, Republic Of, Houston, Texas, United States +25 more

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

NCT ID: NCT03093116

This clinical trial is studying a new treatment called repotrectinib for patients with certain advanced solid tumors that have specific genetic changes known as ALK, ROS1, or NTRK rearrangements. T...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ann Arbor, Michigan, United States, Orange, California, United States +485 more

A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

NCT ID: NCT05836324

This clinical trial is testing a new treatment called INCA33890 for people with advanced or metastatic solid tumors, which are cancers that have spread beyond their original site. The main goal of ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Lyon, , France +39 more

A Multicenter, Prospective, Non-Interventional Real-World Study of Iparomlimab and Tuvonralimab Injection (QL1706) in the Treatment of Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT07046780

This clinical trial is studying how safe and effective a new treatment called QL1706—which combines two medicines, Iparomlimab and Tuvonralimab—is for people with advanced solid tumors. These tumor...

Not yet recruiting

Type: observational Locations: Beijing, , China

Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001)

NCT ID: NCT05853367

This clinical trial, called MK-0472-001, is studying a new treatment called MK-0472 for patients with advanced or metastatic solid tumors, which are types of cancer that have spread beyond their or...

Recruiting

Phase: PHASE1 Type: interventional Locations: Warszawa, Mazowieckie, Poland, Toronto, Ontario, Canada +25 more

Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

NCT ID: NCT07038343

This clinical trial is testing a new drug called AVZO-1418 to see if it is safe and effective in treating certain types of advanced cancers, including lung and other solid tumors that have spread o...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Antonio, Texas, United States, Fairfax, Virginia, United States +2 more

A Study of ERAS-4001 in Patients With Advanced or Metastatic Solid Tumors.

NCT ID: NCT07021898

This clinical trial is studying a new drug called ERAS-4001 in patients who have advanced or metastatic solid tumors, specifically those with certain mutations in a gene called KRAS. The main goal ...

Not yet recruiting

Phase: PHASE1 Type: interventional

A Study of Raludotatug Deruxtecan in Participants With Advanced/Metastatic Solid Tumors (REJOICE-PanTumor01)

NCT ID: NCT06660654

The REJOICE-PanTumor01 clinical trial is studying a new treatment called raludotatug deruxtecan (R-DXd) for adults with advanced or metastatic solid tumors. This includes various types of cancers s...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States, Albany, New York, United States +13 more

NP137 Clinical and Biological Activities Assessment in Patients With Advanced/Metastatic Solid Tumors Treated by Standard Anti PD-1/PD-L1 Immunotherapies

NCT ID: NCT05605496

This clinical trial, called the NP137 study, is exploring the effects of a new treatment, NP137, in combination with standard immunotherapy drugs (like pembrolizumab and atezolizumab) for patients ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Nice, , France, Paris, , France +4 more

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

NCT ID: NCT04094610

This clinical trial is studying a new medication called repotrectinib to see how safe it is and how well it works for treating certain types of advanced cancers in children and young adults. The fo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Los Angeles, California, United States, Philadelphia, Pennsylvania, United States +134 more

Dose Escalation and Expansion Study Evaluating ODC-IL2 in Adult Patients With Advanced or Metastatic Solid Tumors

NCT ID: NCT06770764

This clinical trial is testing a new treatment called ODC-IL2 for adults with advanced or metastatic solid tumors, which are types of cancer that have spread beyond their original site. The study a...

Recruiting

Phase: PHASE1 Type: interventional Locations: Scottsdale, Arizona, United States

A PARG Inhibitor DAT-2645 Monotherapy in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DDR Pathway

NCT ID: NCT06614751

This clinical trial is testing a new treatment called DAT-2645 for patients with advanced solid tumors, particularly those with specific genetic changes known as BRCA1/2 mutations or other issues i...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China, Beijjing, Beijing, China

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