Clinical Trials for Metastatic Uveal Melanoma

Find clinical trials for metastatic uveal melanoma. Discover research opportunities and treatment options in your area.

10 Active Trials Found

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A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

NCT ID: NCT06581406

This clinical trial is exploring the effectiveness and safety of a new treatment combination for patients with metastatic uveal melanoma, a type of eye cancer that has spread to other parts of the ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Durham, North Carolina, United States, Iowa City, Iowa, United States +17 more

Binimetinib Plus Belinostat for Subjects With Metastatic Uveal Melanoma

NCT ID: NCT05170334

This clinical trial is studying the effects of two medications, Binimetinib and Belinostat, in people with metastatic uveal melanoma, a type of eye cancer that has spread to other parts of the body...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States

IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma

NCT ID: NCT05987332

This clinical trial is studying a new combination treatment for people with metastatic uveal melanoma (a type of eye cancer that has spread to other parts of the body). The trial is comparing a tre...

Recruiting

Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States, Boston, Massachusetts, United States +74 more

A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma

NCT ID: NCT05607095

This clinical trial is studying a new treatment called lifileucel (also known as LN-144) for patients with advanced forms of uveal melanoma, undifferentiated pleomorphic sarcoma, or dedifferentiate...

Recruiting

Phase: PHASE1 Type: interventional Locations: Harrison, New York, United States, New York, New York, United States +1 more

Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

NCT ID: NCT06121180

This clinical trial is studying a combination of two medications, Cemiplimab and Ziv-Aflibercept, to see if they are safe and effective for people with metastatic uveal melanoma, which is a type of...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

NCT ID: NCT03025256

This clinical trial is investigating a treatment for patients with leptomeningeal disease, which is a condition where cancer spreads to the membranes surrounding the brain and spinal cord. The stud...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Study of Tebentafusp and Radioembolization in the Treatment of Metastatic Uveal Melanoma

NCT ID: NCT06627244

This clinical trial is studying a new treatment for patients with metastatic uveal melanoma, a type of eye cancer that has spread to the liver. The treatment involves a combination of a medication ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Miami, Florida, United States

Tebentafusp-tebn With LDT in Metastatic UM

NCT ID: NCT06626516

This clinical trial is studying a new treatment called tebentafusp-tebn for patients with metastatic uveal melanoma, a type of eye cancer that has spread to the liver. The trial aims to find out if...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States

Study of IDE196 in Patients with Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

NCT ID: NCT03947385

This clinical trial is studying a new drug called IDE196 to see how safe it is and how well it can help treat certain types of solid tumors, particularly those with specific genetic changes known a...

Recruiting

Phase: PHASE1 Type: interventional Locations: Durham, North Carolina, United States, Los Angeles, California, United States +12 more

A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

NCT ID: NCT05415072

This clinical trial is investigating a new treatment called DYP688 for patients with metastatic uveal melanoma, a type of eye cancer that has spread to other parts of the body, as well as other mel...

Recruiting

Phase: PHASE1 Type: interventional Locations: Westmead, New South Wales, Australia, Essen, , Germany +10 more

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