Clinical Trials for Myelodysplastic Syndromes (MDS)

Find clinical trials for myelodysplastic syndromes (mds). Discover research opportunities and treatment options in your area.

12 Active Trials Found

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Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

NCT ID: NCT05092451

This clinical trial is exploring a new treatment approach for patients with certain blood cancers, including B-Cell Lymphoma, Myelodysplastic Syndromes (MDS), and Acute Myeloid Leukemia (AML). The ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant

NCT ID: NCT04898790

This clinical trial is studying how physical activity can help improve thinking and memory skills in older adults who have recently undergone a stem cell transplant for blood cancers like leukemia ...

Recruiting

Phase: NA Type: interventional Locations: Omaha, Nebraska, United States

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

NCT ID: NCT04064060

This clinical trial is studying the long-term safety of a medication called luspatercept, which is being used to treat conditions like Myelodysplastic Syndromes (MDS), Beta-thalassemia, and certain...

Recruiting

Phase: PHASE3 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Adelaide, South Australia, Australia +283 more

Cord Blood Transplant in Adults With Blood Cancers

NCT ID: NCT05884333

**Trial Summary: Cord Blood Transplant for Adults with Blood Cancers** This clinical trial is studying the effectiveness of cord blood transplants (CBT) as a treatment for adults with certain type...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Montvale, New Jersey, United States +5 more

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

NCT ID: NCT06465953

This clinical trial is studying two different treatment options for patients with myelodysplastic syndromes (MDS) who have a specific genetic mutation called IDH1. The trial is for individuals who ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Boston, Massachusetts, United States, Pavia, , Italy +52 more

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

NCT ID: NCT06656494

This clinical trial is studying the combination of two treatments, ICP-248 and azacitidine, for patients with Acute Myelogenous Leukemia (AML). AML is a type of cancer that affects the blood and bo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China, Zhengzhou, Henan, China +4 more

Involvement of CDA and/or dCK Metabolizing Enzymes in the Response to Azacytidine Treatment of Patients With Hematologic Malignancies

NCT ID: NCT06886425

This clinical trial is studying how the treatment azacytidine works in patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). The goal is to personalize the dose of azacyti...

Recruiting

Phase: NA Type: interventional Locations: Marseille, , France

CART123 T Cells in Relapsed or Refractory CD123+ Hematologic Malignancies: a Dose Escalation Phase I Trial

NCT ID: NCT06765876

This clinical trial is testing a new treatment called CART123 T cells for adults with certain types of blood cancers that have not responded to previous treatments. These cancers include acute myel...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Prague, , Czech Republic

Evaluation of Response to Biosimilar Erythropoietin Alfa Therapy in Anemic Patients With Myelodysplastic Syndrome

NCT ID: NCT06764511

This clinical trial is studying how well a treatment called biosimilar Erythropoietin Alfa (EPO alpha) works for patients with a condition known as Myelodysplastic Syndromes (MDS), specifically for...

Recruiting

Type: observational Locations: Bologna, , Italy

A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS.

NCT ID: NCT04275518

This clinical trial is studying a new treatment called APG-115 for patients with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS), which are types of blood cancers. APG-115 is a med...

Recruiting

Phase: PHASE1 Type: interventional Locations: Shanghai, Shanghai, China, Suzhou, Jiangsu, China +13 more

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

NCT ID: NCT06398457

This clinical trial is studying a new treatment called Darzalex Faspro (daratumumab and hyaluronidase-fihj) to see if it can help patients with high levels of donor-specific antibodies (DSA) who ar...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Baltimore, Maryland, United States

Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes

NCT ID: NCT04997811

The REPAIR-MDS trial is investigating whether repurposed drugs can help improve blood cell production and overall health in patients with Myelodysplastic Syndromes (MDS). MDS is a condition affecti...

Recruiting

Phase: PHASE2 Type: interventional Locations: Dudley, England, United Kingdom, Chelmsford, Essex, United Kingdom +18 more

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