Clinical Trials for Neoadjuvant Therapy

A Clinical Trial of Neoadjuvant Targeted Therapy, Immunotherapy, and Lysogenic HSV-Based Virotherapy in Resectable Head and Neck Squamous Cell Carcinoma

NCT ID: NCT07010120

This clinical trial is looking at a new treatment approach for patients with a type of cancer called head and neck squamous cell carcinoma (HNSCC) that can be surgically removed. The study is explo...

Neoadjuvant SNF Precision Therapy Phase III

NCT ID: NCT06913777

The Neoadjuvant SNF Precision Therapy Phase III clinical trial is studying a new treatment approach for women with early-stage or locally advanced breast cancer that is hormone receptor-positive (H...

Benmelstobart-Anlotinib-Chemo for Neoadjuvant Oral Cancer

NCT ID: NCT06848439

This clinical trial is investigating a new treatment approach for patients with advanced oral cancer, specifically stage III-IVb oral squamous cell carcinoma. The study is looking at a combination ...

Adaptive Neoadjuvant Therapy for Esophageal Cancer

NCT ID: NCT06990178

Iparomlimab and Tuvonralimab Combined With Platinum-Based Chemotherapy for Neoadjuvant Treatment of Cervical Cancer

NCT ID: NCT06986057

This clinical trial is studying the effectiveness and safety of two medications, Iparomlimab and Tuvonralimab, when combined with standard chemotherapy for women with cervical cancer. The goal is t...

The Effect of Neoadjuvant Chemotherapy on Physical Functions

NCT ID: NCT06986005

This clinical trial is studying how neoadjuvant chemotherapy, which is treatment given before surgery for breast cancer, affects physical functioning in women. The researchers want to find out how ...

Neoadjuvant Cadonilimab Combined With Perioperative Oxaliplatin Plus S1 for Diffuse or Mixed Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

NCT ID: NCT06949033

This clinical trial is investigating a new treatment approach for patients with locally advanced gastric or gastroesophageal junction cancer. Specifically, it is looking at whether a drug called ca...

Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

NCT ID: NCT06925243

This clinical trial is studying two different treatment combinations for patients with locally advanced gastric cancer or gastroesophageal junction adenocarcinoma, which is a type of stomach cancer...

Comparison of Neoadjuvant Cadonilimab Versus Chemotherapy Combined With PD-1 in the Treatment of Resectable Non-Small Cell Lung Cancer With High PD-L1 Expression: A Single-Center, Randomized, Exploratory Clinical Study

NCT ID: NCT06946836

This clinical trial is looking at two different treatment options for patients with a type of lung cancer called non-small cell lung cancer (NSCLC) that can be surgically removed. Researchers want ...

Question Prompt List in Breast Cancer Patients Planned for Neoadjuvant Chemotherapy

NCT ID: NCT06777420

This clinical trial is exploring how a tool called a Question Prompt List (QPL) can help women with early-stage breast cancer make informed decisions about their treatment before surgery, specifica...

Development and Prospective Validation of a Multimodal Fusion Artificial Intelligence Model for Predicting the Efficacy of Neoadjuvant Treatment of Bladder Cancer

NCT ID: NCT06909643

This clinical trial is studying a new artificial intelligence (AI) model designed to help doctors predict how well bladder cancer patients will respond to a specific treatment called neoadjuvant th...

Using 4D Urinary Proteomics to Predict and Evaluate Treatment Response in Colorectal Cancer

NCT ID: NCT06904677

This clinical trial is studying how certain proteins found in urine can help predict how patients with locally advanced colorectal cancer (LACC) will respond to a specific treatment called neoadjuv...

Paclitaxel Polymeric Micelles and Carboplatin in Combination With Iparomilimab and Tuvonralimab Neoadjuvant Therapy for Triple-negative Breast Cancer

NCT ID: NCT06910072

This clinical trial is researching a combination of treatments to see how effective and safe they are for women with triple-negative breast cancer, a type of breast cancer that doesn't respond to s...

COGNITION: Genomics-Guided Precision Oncology in Early High-Risk Breast Cancer

NCT ID: NCT05906407

The COGNITION trial is studying how to better tailor treatments for patients with early-stage breast cancer who may not respond well to standard chemotherapy. Researchers are looking at tissue and ...

Neoadjuvant Chemotherapy for Elderly with Pancreatic Head Cancer

NCT ID: NCT06868693

This clinical trial is studying the use of neoadjuvant chemotherapy (NAT) in elderly patients with pancreatic cancer, specifically those aged 70 and older who have tumors that can be surgically rem...

No Axillary Surgical Treatment in Clinically Lymph Node Negative Patients on Ultrasonography After Neoadjuvant Chemotherapy

NCT ID: NCT06704945

The NEO-NAUTILUS clinical trial is studying whether women with breast cancer, who have clinically negative lymph nodes after receiving neoadjuvant chemotherapy, can safely skip surgery to remove ly...

Neoadjuvant Tislelizumab With Chemotherapy for the Treatment of MSS Colon Cancer

NCT ID: NCT06124378

This clinical trial is studying the effects of a treatment that combines Tislelizumab, an immune therapy drug, with chemotherapy for patients with locally advanced microsatellite stable (MSS) colon...

Study of Sinibolimab Combined with Lenvatinib As Neoadjuvant Therapy for Locally Advanced Unresectable Differentiated Thyroid Carcinoma

NCT ID: NCT06848920

This clinical trial is studying a combination of two medications, Sinibolimab and Lenvatinib, to see how effective they are as a treatment before surgery for patients with a specific type of thyroi...

A Clinical Study on the Efficacy and Safety of Paclitaxel Polymeric Micelles and Cisplatin Combined with Cadonilimab As a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma

NCT ID: NCT06356688

This clinical trial is studying a new treatment approach for patients with locally advanced esophageal squamous cell carcinoma, which is a type of cancer affecting the esophagus. Researchers want t...

Evaluation of Neoadjuvant Therapy Efficacy and Postoperative Pathological Indicators in Esophageal Cancer Using CT and Multimodal MRI

NCT ID: NCT06833775

This clinical trial is looking to understand how effective different types of treatments, called neoadjuvant therapies, are for patients with esophageal cancer before they undergo surgery. Neoadjuv...