Osimertinib With Chemotherapy as First-line Therapy for EGFR Mutation-positive NSCLC

NCT ID: NCT06376084

This clinical trial is looking at a new treatment approach for patients with a specific type of lung cancer called non-small cell lung cancer (NSCLC) that has certain genetic changes (EGFR mutation...

Recruiting

Type: observational Locations: Shanghai, , China, Shanghai, , China

Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer

NCT ID: NCT05386108

This clinical trial is investigating a combination of two medications, abemaciclib and elacestrant, to see how well they work for patients with brain metastases from estrogen receptor-positive (ER+...

Recruiting

Phase: PHASE1 Type: interventional Locations: Urbana, Illinois, United States, Boston, Massachusetts, United States +96 more

Early Intervention Strategies for Lung Cancer

NCT ID: NCT06988943

This clinical trial, titled "Early Intervention Strategies for Lung Cancer," is focused on finding out how effective and cost-efficient low-dose CT (LDCT) scans are for detecting lung cancer early....

Recruiting

Phase: NA Type: interventional Locations: Guangzhou, Guangdong, China

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

NCT ID: NCT06988475

The DETERMINE Trial is researching a medication called capmatinib, which is typically used to treat certain types of lung cancer. This study aims to see if capmatinib can also help adults with othe...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Southampton, , United Kingdom +14 more

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition

NCT ID: NCT05770102

The DETERMINE Trial Treatment Arm 02 is studying a drug called atezolizumab, which is already used to treat certain types of cancer in adults. This trial aims to see if atezolizumab can help patien...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +26 more

Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617

NCT ID: NCT06785636

This clinical trial is looking at a new treatment option for men with metastatic castration-resistant prostate cancer (mCRPC), which is a type of advanced prostate cancer that no longer responds to...

Recruiting

Phase: PHASE1 Type: interventional Locations: Durham, North Carolina, United States, Houston, Texas, United States +5 more

DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-positive Cancers.

NCT ID: NCT05770544

The DETERMINE Trial is studying a medication called entrectinib to see if it can help treat various types of cancers that have a specific genetic change known as ROS1 gene fusion. While entrectinib...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +26 more

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

NCT ID: NCT05770037

The DETERMINE Trial is studying a drug called alectinib, which is already used to treat certain types of lung cancer in adults. Researchers want to see if this medication can also help treat other ...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Leeds, , United Kingdom +26 more

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NCT ID: NCT03911388

This clinical trial is studying a new treatment called G207, which is an experimental virus therapy designed to target certain types of brain tumors in children and young adults. Specifically, it f...

Recruiting

Phase: PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States, Houston, Texas, United States +1 more

Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab

NCT ID: NCT06237920

This clinical trial is looking at new treatment options for patients with Stage II-IIIa urothelial cancer, which is a type of bladder cancer. The study is comparing two treatment approaches: one gr...

Recruiting

Phase: PHASE2 Type: interventional Locations: Utrecht, , Netherlands, Amsterdam, Noord Holland, Netherlands +5 more

Real World Registry for Use of the Ion Endoluminal System

NCT ID: NCT06004440

This clinical trial is looking at how well the Ion Endoluminal System works for locating and taking samples from lung lesions, which are abnormal growths in the lungs. The goal is to see how effect...

Recruiting

Type: observational Locations: Detroit, Michigan, United States, Pinehurst, North Carolina, United States +15 more

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

NCT ID: NCT05592626

This clinical trial is testing a new treatment called STAR0602, which is a special type of antibody designed to target certain solid tumors in patients whose cancer has advanced and cannot be treat...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Miami, Florida, United States +11 more

Small/Middle Tier Cities and County Lung Cancer Quality Improvement Project (QIP) Study

NCT ID: NCT06494241

The Small/Middle Tier Cities and County Lung Cancer Quality Improvement Project (QIP) Study is a clinical trial designed to learn more about how doctors are testing and treating patients with advan...

Recruiting

Type: observational Locations: Guangzhou, , China, Suzhou, , China +51 more

Research Project on Reminders and Self-Sampling Can Increase Participation in Gynecology Cell Sampling - Preventive Examination Against Cervical Cancer.

NCT ID: NCT04061967

This clinical trial is studying how different ways of reminding women to get screened for cervical cancer can increase participation in these important screenings. Cervical cancer screening has bee...

Recruiting

Phase: NA Type: interventional Locations: Lund, Skåne, Sweden, Umeå, Västerbotten, Sweden +8 more

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

NCT ID: NCT06706921

This clinical trial is studying how a specific imaging test called 18F-Fluciclovine PET/CT can help predict how well a treatment called Lutetium-PSMA-617 therapy works for men with advanced prostat...

Recruiting

Phase: PHASE4 Type: interventional Locations: Los Angeles, California, United States

Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2

NCT ID: NCT05980416

This clinical trial is studying a new treatment called EO-3021 for adult patients with certain types of solid tumors, like pancreatic and stomach cancers, that are likely to have a specific protein...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, New York, New York, United States +19 more

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma

NCT ID: NCT04572451

This clinical trial is studying a new treatment approach for patients with advanced solid tumors, including melanoma, that cannot be surgically removed. The researchers are testing a combination of...

Recruiting

Phase: PHASE1 Type: interventional Locations: Chicago, Illinois, United States, Pittsburgh, Pennsylvania, United States

OSPREY is a Post-market, Global, Multicentre, Observational, Prospective Registry.

NCT ID: NCT04493632

The OSPREY trial is a study designed to collect information about the OncoSil™ device, which is used to treat patients with locally advanced pancreatic cancer that cannot be surgically removed. Thi...

Recruiting

Type: observational Locations: Madrid, , Spain, Madrid, , Spain +7 more

Evaluate the Efficacy of Adding Intraluminal Brachytherapy After CCRT for Local-regional Thoracic Esophageal Cancer.

NCT ID: NCT06365866

This clinical trial is looking at a new treatment option for patients with thoracic esophageal cancer. Researchers want to see how well a special type of radiation therapy called intraluminal brach...

Recruiting

Phase: NA Type: interventional Locations: Taipei, , Taiwan

A Phase Ⅱ Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLC

NCT ID: NCT06177925

This clinical trial is studying a new treatment for patients with extensive-stage oligometastatic small cell lung cancer (SCLC), a type of lung cancer that has spread to other parts of the body. Th...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, , China

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Clinical Trials for Neoplasms by Site

23 Active Trials Found

Osimertinib With Chemotherapy as First-line Therapy for EGFR Mutation-positive NSCLC

Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Early Intervention Strategies for Lung Cancer

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition

Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617

DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-positive Cancers.

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab

Real World Registry for Use of the Ion Endoluminal System

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Small/Middle Tier Cities and County Lung Cancer Quality Improvement Project (QIP) Study

Research Project on Reminders and Self-Sampling Can Increase Participation in Gynecology Cell Sampling - Preventive Examination Against Cervical Cancer.

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma

OSPREY is a Post-market, Global, Multicentre, Observational, Prospective Registry.

Evaluate the Efficacy of Adding Intraluminal Brachytherapy After CCRT for Local-regional Thoracic Esophageal Cancer.

A Phase Ⅱ Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLC

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