Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

NCT ID: NCT06172296

This clinical trial is studying a new treatment approach for children with high-risk neuroblastoma, a type of cancer that affects nerve cells. The researchers want to find out if combining a medici...

Recruiting

Phase: PHASE3 Type: interventional Locations: New Haven, Connecticut, United States, Durham, North Carolina, United States +159 more

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

NCT ID: NCT06942039

This clinical trial is a pilot study designed to explore the safety and effectiveness of a new treatment approach for young children under 6 years old who are newly diagnosed with high-risk embryon...

Not yet recruiting

Phase: EARLY_PHASE1 Type: interventional

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT ID: NCT06395103

This clinical trial, called Substudy 01A, is investigating a new treatment called zilovertamab vedotin for children and young adults with certain types of blood cancers and solid tumors. Specifical...

Recruiting

Phase: PHASE1 Type: interventional Locations: Münster, Nordrhein Westfalen, Germany, São José Do Rio Preto, Sao Paulo, Brazil +63 more

A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma

NCT ID: NCT06057948

This clinical trial is studying a new treatment approach for children and young adults with high-risk neuroblastoma, a type of cancer that can be very serious and challenging to treat. The research...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Montvale, New Jersey, United States +5 more

SIOPEN BIOPORTAL, An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic Tumours

NCT ID: NCT05192980

The SIOPEN BIOPORTAL is an international study designed to create a registry and virtual bank of samples for patients with certain types of tumors called peripheral neuroblastic tumors, which inclu...

Recruiting

Phase: NA Type: interventional Locations: Lille, , France, St. Gallen, , Switzerland +36 more

Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma

NCT ID: NCT00107289

This clinical trial is studying a treatment called Iodine I 131 Metaiodobenzylguanidine (131 I-MIBG) for patients with difficult-to-treat neuroblastoma, malignant pheochromocytoma, or paraganglioma...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

NCT ID: NCT06995872

This clinical trial is testing a new treatment for children and young adults with a type of cancer called neuroblastoma, particularly for those whose cancer has not responded to previous treatments...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

NCT ID: NCT01005654

This clinical trial is focused on understanding endocrine neoplasms, which are tumors that can occur in glands like the thyroid, parathyroid, adrenal glands, and pancreas. These tumors are becoming...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, Bethesda, Maryland, United States

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

NCT ID: NCT06625190

This clinical trial is investigating a new treatment approach for certain solid tumors in young patients, including conditions like neuroblastoma and rhabdomyosarcoma. The treatment involves using ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Gainesville, Florida, United States

Safety & Efficacy of IR-101 in Relapsed/Refractory Neuroblastoma

NCT ID: NCT07067346

This clinical trial is studying a new treatment called IR-101 for children with neuroblastoma, a type of cancer that has come back or has not responded to previous treatments. IR-101 is a special k...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Chengdu, Sichuang, China

Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma

NCT ID: NCT07027748

This clinical trial is studying a new way to give a combination of treatments—including chemotherapy drugs (irinotecan and temozolomide), an immune system booster (sargramostim), and a targeted imm...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Study Combining Dinutuximab Beta With Two Chemotherapy Regimens in Neuroblastoma

NCT ID: NCT06485947

This clinical trial is investigating a new treatment approach for children and young adults with high-risk neuroblastoma, a type of cancer that primarily affects young children. The study aims to f...

Recruiting

Phase: PHASE1 Type: interventional Locations: Utrecht, , Netherlands

A Study of a Vaccine in Combination With β-glucan and GM-CSF in People With Neuroblastoma

NCT ID: NCT04936529

This clinical trial is testing a new treatment approach for children and young adults with high-risk neuroblastoma, a type of cancer. The study is looking at a combination of a special vaccine, a s...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States

Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies

NCT ID: NCT01109394

This clinical trial is focused on collecting and storing samples from individuals diagnosed with common childhood cancers, such as leukemia, sarcoma, neuroblastoma, retinoblastoma, and renal cancer...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States, Washington, District Of Columbia, United States +3 more

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

NCT ID: NCT06528496

The N10 clinical trial is looking at a new way to treat children with high-risk neuroblastoma, a type of cancer that can be very challenging to manage. The study aims to see if a treatment called N...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States

Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastoma

NCT ID: NCT06013618

This clinical trial is studying a new treatment called naxitamab for children with high-risk neuroblastoma, which is a type of cancer that primarily affects young children. The trial is looking at ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, , China, Guangzhou, Guangdong, China

Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome

NCT ID: NCT00588068

**Clinical Trial Summary: Molecular Characterization of Neuroblastic Tumor** This clinical trial aims to better understand neuroblastic tumors, a type of cancer that can affect children. Researche...

Recruiting

Type: observational Locations: New York, New York, United States

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT ID: NCT03618381

This clinical trial is looking at a new type of treatment called EGFR806 CAR T Cell Immunotherapy for children and young adults with certain types of solid tumors that have returned or didn’t respo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

NCT ID: NCT05135975

This clinical trial is exploring the use of a medication called cabozantinib as a maintenance treatment for children and young adults with high-risk solid tumors, specifically neuroblastoma and sar...

Recruiting

Phase: PHASE2 Type: interventional Locations: Washington, District Of Columbia, United States, Columbus, Ohio, United States +4 more

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

NCT ID: NCT06988475

The DETERMINE Trial is researching a medication called capmatinib, which is typically used to treat certain types of lung cancer. This study aims to see if capmatinib can also help adults with othe...

Recruiting

Phase: PHASE2 Type: interventional Locations: London, , United Kingdom, Southampton, , United Kingdom +14 more

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Clinical Trials for Neuroblastoma

76 Active Trials Found

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma

SIOPEN BIOPORTAL, An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic Tumours

Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

Safety & Efficacy of IR-101 in Relapsed/Refractory Neuroblastoma

Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma

Study Combining Dinutuximab Beta With Two Chemotherapy Regimens in Neuroblastoma

A Study of a Vaccine in Combination With β-glucan and GM-CSF in People With Neuroblastoma

Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastoma

Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

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