Clinical Trials for Non Small Cell Lung Cancer

Find clinical trials for non small cell lung cancer. Discover research opportunities and treatment options in your area.

257 Active Trials Found

Showing 257 trials on this page

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Implementing Circulating Tumor DNA Analysis at Initial Diagnosis to Improve Management of Advanced NSCLC Patients

NCT ID: NCT04912687

This clinical trial is studying how well a new test called liquid biopsy can detect a specific gene mutation (EGFR) in patients with advanced non-small cell lung cancer (NSCLC). The aim is to see i...

Recruiting

Phase: NA Type: interventional Locations: Bordeaux, , France, Poitiers, , France +7 more

A Study of CD8+ T Cell Imaging During Treatment in People With Non-Small Cell Lung Cancer

NCT ID: NCT06863233

This clinical trial is investigating a new method to help doctors see specific immune cells called CD8+ T cells in patients with metastatic non-small cell lung cancer (NSCLC). These cells play a cr...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Montvale, New Jersey, United States +5 more

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

NCT ID: NCT06694454

This clinical trial is studying a new treatment approach for early-stage non-small cell lung cancer (NSCLC), which is the most common type of lung cancer. Researchers want to see if inhaling a drug...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

NCT ID: NCT04928846

This clinical trial is studying a new treatment called telisotuzumab vedotin for adults with non-small cell lung cancer (NSCLC) who have already received treatment in the past. Researchers want to ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Los Angeles, California, United States, Rancho Mirage, California, United States +495 more

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

NCT ID: NCT06999187

This clinical trial is looking at a new treatment called DR-0202 for patients with certain types of advanced cancers, including triple-negative breast cancer and non-small cell lung cancer, among o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Fairfax, Virginia, United States, Denver, Colorado, United States +8 more

Sunvozertinib Treatment in Untreated Advanced NSCLC With EGFR Uncommon Mutations

NCT ID: NCT07117890

This clinical trial is studying a new treatment called sunvozertinib for people with advanced non-small cell lung cancer (NSCLC) who have specific, less common changes (mutations) in a gene called ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China

STK-012 Monotherapy and in Combination Therapy in Patients With Solid Tumors

NCT ID: NCT05098132

This clinical trial is looking at a new treatment called STK-012 for patients with certain advanced solid tumors, which are types of cancer that form in various organs. The trial will test STK-012 ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +27 more

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

NCT ID: NCT05983432

This clinical trial is studying a new treatment called BL-B01D1 for patients with metastatic or unresectable non-small cell lung cancer (NSCLC) and other solid tumors, such as certain types of brea...

Recruiting

Phase: PHASE1 Type: interventional Locations: Orange, California, United States, Boston, Massachusetts, United States +43 more

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

NCT ID: NCT06312137

This clinical trial is investigating whether a combination of two treatments, pembrolizumab and sacituzumab tirumotecan, can help patients with a type of lung cancer called non-small cell lung canc...

Recruiting

Phase: PHASE3 Type: interventional Locations: Warszawa, Mazowieckie, Poland, Santiago, Region M. De Santiago, Chile +259 more

Effect of G-CSF on MDSC and Cancer Stem-cells Interactions in Non-small Cell Lung Cancers (CIRCUIT)

NCT ID: NCT06711770

The CIRCUIT trial is studying how a medication called Granulocyte Colony Stimulating Factor (G-CSF) affects certain cells in the blood of patients with non-small cell lung cancer (NSCLC). This type...

Not yet recruiting

Phase: NA Type: interventional Locations: Bordeaux, , France

First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy

NCT ID: NCT06439914

This clinical trial is looking at a new imaging technique using a special agent called \[89Zr\]Zr-DFO-emapalumab to see how well immunotherapy works for patients with non-small cell lung cancer (NS...

Recruiting

Phase: PHASE1 Type: interventional Locations: Detroit, Michigan, United States

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

NCT ID: NCT06810544

This clinical trial is looking at a new treatment called TNG456, which is being tested alone and together with another medication called abemaciclib for patients with advanced solid tumors that hav...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Columbus, Ohio, United States +4 more

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

NCT ID: NCT06060613

This clinical trial is studying a new treatment called OBX-115 for adults with advanced solid tumors, such as metastatic melanoma and non-small cell lung cancer. The main goal of the trial is to se...

Recruiting

Phase: PHASE1 Type: interventional Locations: Louisville, Kentucky, United States, Columbus, Ohio, United States +15 more

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

NCT ID: NCT05887492

This clinical trial is studying a new treatment combination for patients with advanced solid tumors that have a specific genetic mutation called STK11. The treatment involves a drug called TNG260, ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Detroit, Michigan, United States +10 more

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

NCT ID: NCT06789172

This clinical trial is testing a new drug called OKN4395, both on its own and together with another medication called pembrolizumab, in patients with different types of solid tumors like sarcoma an...

Recruiting

Phase: PHASE1 Type: interventional Locations: Santa Monica, California, United States, Oxford, , United Kingdom +6 more

Efficacy and Safety Analysis of First-Line ABCP Therapy in Advanced SMARCA4-Mutated NSCLC

NCT ID: NCT07093762

This clinical trial is studying a new combination treatment called ABCP for people with advanced non-small cell lung cancer (NSCLC) who have a specific genetic change called a SMARCA4 mutation. Thi...

Not yet recruiting

Type: observational Locations: Fuzhou, , China

Evaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors

NCT ID: NCT06714617

This clinical trial is investigating a new treatment called BL-M17D1 for patients with advanced or metastatic solid tumors that have a specific protein called HER2. The study aims to evaluate how s...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Indianapolis, Indiana, United States +10 more

A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1)

NCT ID: NCT06905197

This clinical trial, called TIAN-SHAN1, is studying a new oral medication named DZD6008 for patients with advanced non-small cell lung cancer (NSCLC) who have specific mutations in the EGFR gene. T...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States

Prophylactic Proton Pump Inhibition for Esophageal Protection in Lung Radiation Therapy

NCT ID: NCT07076914

This clinical trial is studying whether taking a daily medicine called a proton pump inhibitor (PPI), which reduces stomach acid, can help protect the esophagus (the tube that carries food from the...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: London, Ontario, Canada

Using Urine Samples to Identify Lung Cancer

NCT ID: NCT06033248

This clinical trial is exploring a new way to detect non-small cell lung cancer (NSCLC) using urine samples. Researchers are using specially trained animals that can smell certain chemicals in urin...

Recruiting

Type: observational Locations: New York, New York, United States, Harrison, New York, United States +5 more

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