Clinical Trials for PALB2 Gene Mutation

Find clinical trials for palb2 gene mutation. Discover research opportunities and treatment options in your area.

8 Active Trials Found

Showing 8 trials on this page

Page 1 of 1

Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations

NCT ID: NCT06392841

This clinical trial is studying a combination of three medications—Niraparib, Abiraterone Acetate, and Prednisone— to see how well they work for men with metastatic hormone-sensitive prostate cance...

Recruiting

Phase: PHASE2 Type: interventional Locations: Dallas, Texas, United States, Chicago, Illinois, United States

Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors

NCT ID: NCT06177171

This clinical trial is investigating a new treatment combining two medications: olaparib and ASTX727. It focuses on adults with advanced solid tumors that have specific genetic mutations related to...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Francisco, California, United States

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

NCT ID: NCT05420064

This clinical trial is designed to improve how families manage genetic testing for cancer risks, particularly for those who may carry certain gene mutations linked to cancer. The study has two part...

Recruiting

Phase: NA Type: interventional Locations: New York, New York, United States, New York, New York, United States +7 more

Study of NABPLAGEM vs. Nab-Paclitaxel/Gemcitabine in BRCA1/2 or PALB2 Pancreatic Cancer

NCT ID: NCT06783140

This clinical trial is investigating two different treatments for patients with advanced pancreatic cancer who have specific genetic mutations (BRCA1/2 or PALB2) and have not responded well to thei...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Toronto, Ontario, Canada

Combination Therapy in Cancers With Mutations in DNA Repair Genes

NCT ID: NCT05694715

This clinical trial is studying a combination of two medications—niraparib and irinotecan—to see if they can be safely used together to treat certain types of advanced cancers that have specific ge...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Francisco, California, United States

The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation.

NCT ID: NCT05097274

The GENPET Study is a clinical trial designed to see how effective a specific type of imaging, called FCH-PET-CT, is for detecting prostate cancer that has spread beyond the pelvis in men who have ...

Recruiting

Type: observational Locations: London, Sutton, Surrey, United Kingdom, London, , United Kingdom

Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion

NCT ID: NCT06033092

This clinical trial is investigating whether a low dose of tamoxifen (a medication often used to prevent breast cancer) can help increase levels of a protein called Sex Hormone Binding Globulin (SH...

Recruiting

Phase: PHASE2 Type: interventional Locations: Milan, , Italy, Padova, , Italy +2 more

SHARON: A Clinical Trial for Metastatic Cancer With a BRCA or PALB2 Mutation Using Chemotherapy and Patients' Own Stem Cells

NCT ID: NCT04150042

The SHARON clinical trial is studying a new treatment approach for patients with advanced (stage IV) cancer who have specific genetic mutations called BRCA1, BRCA2, or PALB2. This treatment combine...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States

Related Conditions

Breast Cancer View clinical trials → Stroke View clinical trials → Obesity View clinical trials → Cancer View clinical trials → Healthy View clinical trials → Prostate Cancer View clinical trials →

Search All Trials Browse All Conditions