Clinical Trials for Pancreatic Ductal Adenocarcinoma

Find clinical trials for pancreatic ductal adenocarcinoma. Discover research opportunities and treatment options in your area.

93 Active Trials Found

Showing 93 trials on this page

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A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

NCT ID: NCT06428409

This clinical trial is investigating a new treatment called sacituzumab tirumotecan (MK-2870) to see how well it works alone or in combination with chemotherapy for certain advanced gastrointestina...

Recruiting

Phase: PHASE1 Type: interventional Locations: Brisbane, Queensland, Australia, Fuzhou, Fujian, China +58 more

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

NCT ID: NCT06084481

This clinical trial is studying a new treatment called ABBV-400 for adults with advanced solid tumors, such as liver cancer, pancreatic cancer, and certain types of breast and ovarian cancers. The ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Grand Rapids, Michigan, United States, Durham, North Carolina, United States +64 more

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

NCT ID: NCT06586515

This clinical trial is studying a new treatment called LY3962673 for patients with certain types of advanced cancer, specifically those with a KRAS G12D mutation. The main goal of the study is to e...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Durham, North Carolina, United States +91 more

Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer

NCT ID: NCT05132504

This clinical trial is testing a new treatment approach for patients with early-stage pancreatic cancer that can be surgically removed, called pancreatic ductal adenocarcinoma. The study combines a...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States, Houston, Texas, United States +1 more

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

NCT ID: NCT06607185

This clinical trial is studying a new medication called LY4066434, which is designed to target specific mutations in a gene called KRAS found in certain types of cancer. The trial focuses on patien...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Durham, North Carolina, United States +74 more

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

NCT ID: NCT06131840

This clinical trial is investigating an experimental drug called PF-08046050, which is designed to treat adults with advanced solid tumors, including types of cancer like colorectal, stomach, pancr...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, Boston, Massachusetts, United States +49 more

POP-UP: a Single-arm, Two-cohort Study: Trimodal Prehab for Upper GI and Pancreatic Cancer

NCT ID: NCT06275737

The POP-UP clinical trial is exploring a new approach to help patients with localized pancreatic cancer or esophageal cancer prepare for surgery and chemotherapy. This study is testing an 8-week pr...

Recruiting

Phase: NA Type: interventional Locations: Marseille, , France, Lille, , France +2 more

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

NCT ID: NCT06562192

This clinical trial is studying a new treatment called [177Lu]Lu-NNS309 for patients with advanced stages of certain types of cancer, including pancreatic, lung, breast, and colorectal cancers. The...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Stanford, California, United States +9 more

Pancreatic Cancer Detection Consortium

NCT ID: NCT06388967

The Pancreatic Cancer Detection Consortium is a clinical trial aimed at finding a new way to detect pancreatic cancer early and without invasive procedures. The researchers are studying a specific ...

Recruiting

Type: observational Locations: Milwaukee, Wisconsin, United States, Seoul, , Korea, Republic Of +10 more

Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor

NCT ID: NCT06105021

This clinical trial is studying a new treatment called AFNT-211 for patients with advanced solid tumors that have a specific genetic change known as the KRAS G12V mutation. This mutation is commonl...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Nashville, Tennessee, United States +10 more

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

NCT ID: NCT06503146

This clinical trial is studying a new imaging method using a special substance called 18F-FAPI-74 to help detect certain types of cancer more effectively. The goal is to find out if this new tracer...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

NCT ID: NCT06445062

This clinical trial is studying a new type of treatment called RAS(ON) inhibitors for patients with certain types of gastrointestinal cancers, specifically colorectal cancer and pancreatic cancer. ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, Philadelphia, Pennsylvania, United States +22 more

A Phase 1/2a Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

NCT ID: NCT07020221

This clinical trial is studying a new treatment called VS-7375 for patients with certain types of advanced solid tumors that have a specific genetic change known as the KRAS G12D mutation. The goal...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Saint Louis, Missouri, United States +3 more

Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer

NCT ID: NCT05799274

This clinical trial is studying the safety of a new treatment called RAD301, which is a type of radioisotope that will be given through an IV. The trial includes both healthy volunteers and patient...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bronx, New York, United States, Princeton, New Jersey, United States

PET Imaging Using 64Cu-Tz-SarAr and hu5B1-TCO in People With Pancreatic, Colorectal, Bladder Cancer or Cancers With Elevated CA19.9

NCT ID: NCT05737615

This clinical trial is studying a new imaging technique that uses a special substance called hu5B1-TCO and a radioactive material known as 64Cu-Tz-SarAr. The goal is to find the safest dose of thes...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

NCT ID: NCT06673017

This clinical trial, titled PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC), is investigating a new treatment for patients with pancreatic cancer that is either borderline resectable or locally ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Newport Beach, California, United States, Seattle, Washington, United States +2 more

Liquid Biopsy and Pancreas Cancer: Detection of AXL(+) CTCs (CTC-AXL-PANC)

NCT ID: NCT05346536

This clinical trial is studying a new way to detect certain cancer cells that break away from pancreatic tumors and travel through the bloodstream. These traveling cells, called circulating tumor c...

Recruiting

Phase: NA Type: interventional Locations: Montpellier, , France

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

NCT ID: NCT05783622

This clinical trial is studying a new treatment called JANX008 for adults with advanced or metastatic solid tumors, such as certain types of lung cancer, kidney cancer, and breast cancer. The aim i...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ann Arbor, Michigan, United States, St. Louis, Missouri, United States +16 more

French Assessment of MRD by Liquid Biopsies in PDAC Patients (FRENCH.MRD.PDAC)

NCT ID: NCT06287749

The FRENCH.MRD.PDAC trial is studying a type of blood test called a liquid biopsy to see if it can help doctors predict the risk of pancreatic cancer returning after treatment. Specifically, resear...

Recruiting

Type: observational Locations: Montpellier, , France

A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors

NCT ID: NCT05983133

This clinical trial is investigating a new drug called SGN-EGFRd2, aimed at treating patients with advanced solid tumors, including certain types of colorectal cancer, lung cancer, and pancreatic c...

Recruiting

Phase: PHASE1 Type: interventional Locations: Iowa City, Iowa, United States, Tampa, Florida, United States +33 more

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