Clinical Trials for Paroxysmal Nocturnal Hemoglobinuria

Find clinical trials for paroxysmal nocturnal hemoglobinuria. Discover research opportunities and treatment options in your area.

21 Active Trials Found

Showing 21 trials on this page

Page 1 of 2

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

NCT ID: NCT06412497

This clinical trial, titled MT2023-20, is exploring a new treatment approach for patients with severe aplastic anemia and other related conditions that affect the bone marrow, such as paroxysmal no...

Recruiting

Phase: PHASE2 Type: interventional Locations: Minneapolis, Minnesota, United States

Specified Drug-use Surveillance of Fabhalta Capsules

NCT ID: NCT06606314

This clinical trial is studying Fabhalta capsules, a treatment for a rare blood condition called Paroxysmal Nocturnal Hemoglobinuria (PNH). The trial is designed to gather information about how wel...

Recruiting

Type: observational Locations: Nagoya, Aichi, Japan, Sapporo, Hokkaido, Japan +38 more

A Multi-center, Ambispective Cohort Study to Evaluate the Impact of Iptacopan for Adult Patients With PNH in China

NCT ID: NCT06931691

This clinical trial is studying the effects of a new treatment called iptacopan for adults with Paroxysmal Nocturnal Hemoglobinuria (PNH), a rare blood disorder. Researchers want to see how well ip...

Recruiting

Type: observational Locations: Tianjin, , China

A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment

NCT ID: NCT05133531

This clinical trial is studying a new combination treatment using two experimental drugs called pozelimab and cemdisiran for adults with a condition known as paroxysmal nocturnal hemoglobinuria (PN...

Recruiting

Phase: PHASE3 Type: interventional Locations: Toronto, Ontario, Canada, Barcelona, , Spain +124 more

Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis

NCT ID: NCT06449001

This clinical trial is studying a new treatment called danicopan for children and teenagers with a condition known as paroxysmal nocturnal hemoglobinuria (PNH). PNH can cause serious anemia, which ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Paris, , France

Long-term Safety and Tolerability of HRS-5965 in Patients With Paroxysmal Nocturnal Hemoglobinuria

NCT ID: NCT06238544

This clinical trial is studying the long-term safety and tolerability of a medication called HRS-5965 in patients who have a condition known as Paroxysmal Nocturnal Hemoglobinuria (PNH). PNH is a r...

Recruiting

Phase: PHASE2 Type: interventional Locations: Beijing, Beijing, China, Tianjin, Tianjin, China

A Real World Effectiveness Study of Pegcetacoplan in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

NCT ID: NCT05776472

This clinical trial is studying the effectiveness of a medication called pegcetacoplan in treating patients with a rare blood condition known as Paroxysmal Nocturnal Hemoglobinuria (PNH). The trial...

Recruiting

Type: observational Locations: London, , United Kingdom, Liverpool, New South Wales, Australia +100 more

Study of Safety and Efficacy of MY008211A in Patients With Residual Anemia Despite Anti-C5 Antibody Treatment

NCT ID: NCT06932471

This clinical trial is studying a new treatment called MY008211A for patients with a condition called Paroxysmal Nocturnal Hemoglobinuria (PNH). PNH can cause anemia, which means your body doesn’t ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Beijing, Beijing, China

Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF

NCT ID: NCT03047746

This clinical trial is studying a new approach to treat patients with certain bone marrow failure conditions, such as acquired aplastic anemia and inherited bone marrow failure syndromes. The resea...

Recruiting

Phase: NA Type: interventional Locations: Philadelphia, Pennsylvania, United States

A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works.

NCT ID: NCT05744921

This clinical trial is studying the safety and effectiveness of a new combination treatment using two experimental drugs called pozelimab and cemdisiran for adults with paroxysmal nocturnal hemoglo...

Recruiting

Phase: PHASE3 Type: interventional Locations: Barcelona, , Spain, Singapore, , Singapore +57 more

Study of NM8074 in Adult PNH Patients with Inadequate Response to Soliris

NCT ID: NCT05646563

This clinical trial is studying a new treatment called NM8074 for adults with Paroxysmal Nocturnal Hemoglobinuria (PNH) who have not responded well to an existing medication called Soliris. The goa...

Not yet recruiting

Phase: PHASE2 Type: interventional

Study of Efficacy and Safety of NM8074 in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy

NCT ID: NCT05646524

This clinical trial is studying a new treatment called NM8074 for adults with Paroxysmal Nocturnal Hemoglobinuria (PNH), a rare blood disorder. The goal is to see how safe and effective NM8074 is w...

Not yet recruiting

Phase: PHASE2 Type: interventional

Global PNH Patient Registry

NCT ID: NCT05755867

The Global PNH Patient Registry is a clinical trial designed to gather important information about Paroxysmal Nocturnal Hemoglobinuria (PNH), a rare blood disorder caused by a genetic mutation. The...

Recruiting

Type: observational Locations: Bethesda, Maryland, United States

Home Reported Outcomes in PNH

NCT ID: NCT06411626

This clinical trial, titled "Home Reported Outcomes in PNH," is studying how patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) experience their symptoms and overall quality of life over time....

Recruiting

Type: observational Locations: East Hanover, New Jersey, United States

Efficacy and Safety of HRS-5965 in Patients With PNH Who Are Still Anemia After Anti-C5 Antibody Treatment

NCT ID: NCT06715943

This clinical trial is exploring a new treatment called HRS-5965 for patients with a rare blood disorder known as paroxysmal nocturnal hemoglobinuria (PNH). The study is aimed at individuals who ar...

Recruiting

Phase: PHASE3 Type: interventional Locations: Tianjin, Tianjin, China, Tianjin, Tianjin, China

A Study of NTQ5082 Capsules in the Treatment of Paroxysmal Nocturnal Hemoglobinuria Patients

NCT ID: NCT06764303

This clinical trial is studying a new medication called NTQ5082, which comes in capsule form, to see how well it works for treating patients with a rare blood condition known as paroxysmal nocturna...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Hangzhou, Zhejiang, China, Tianjin, Tianjin, China

Long-term Safety and Tolerability of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria

NCT ID: NCT06745622

This clinical trial is looking at a medication called HSK39297 to see how safe it is and how well it works for people with a condition called Paroxysmal Nocturnal Hemoglobinuria (PNH). The study is...

Recruiting

Phase: PHASE2 Type: interventional Locations: Nanjing, Jiangsu, China

To Evaluate the Effect of Single Oral Dose of MY008211A Tablets on QTc Interval in Healthy Subjects

NCT ID: NCT06543459

This clinical trial is designed to study the effects of a new medication called MY008211A on heart rhythm in healthy adults. Specifically, researchers are looking at how a single dose of this medic...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Beijing, Beijing, China

The International PNH Interest Group PNH Registry

NCT ID: NCT06524726

The International PNH Interest Group (IPIG) has started a registry to gather important information about patients with Paroxysmal Nocturnal Hemoglobinuria (PNH), a rare blood condition. This regist...

Recruiting

Type: observational Locations: Altamonte Springs, Florida, United States

Long-Term Safety, Tolerability and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria

NCT ID: NCT06298955

This clinical trial is investigating the long-term safety and effectiveness of a treatment called OMS906 for patients with Paroxysmal Nocturnal Hemoglobinuria (PNH), a rare blood condition. Partici...

Recruiting

Phase: PHASE2 Type: interventional Locations: Kyiv, , Ukraine, Aachen, , Germany +3 more

Related Conditions

Breast Cancer View clinical trials → Stroke View clinical trials → Obesity View clinical trials → Cancer View clinical trials → Healthy View clinical trials → Prostate Cancer View clinical trials →

Search All Trials Browse All Conditions