Clinical Trials for Prostatic Neoplasms, Castration-Resistant

Find clinical trials for prostatic neoplasms, castration-resistant. Discover research opportunities and treatment options in your area.

11 Active Trials Found

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A Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Participants With Castration-Resistant Prostate Cancer

NCT ID: NCT02592317

This clinical trial is studying a treatment called JNJ-56021927 to see how it affects the way the body processes certain medications in men with castration-resistant prostate cancer, a type of pros...

Recruiting

Phase: PHASE1 Type: interventional Locations: Barcelona, , Spain, Sevilla, , Spain +5 more

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

NCT ID: NCT06353386

This clinical trial, named Substudy 01A, is exploring whether a new treatment called opevesostat, either on its own or combined with other therapies, is safe and effective for men with metastatic c...

Recruiting

Phase: PHASE1 Type: interventional Locations: Cork, , Ireland, Munich, Bayern, Germany +95 more

64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)

NCT ID: NCT04868604

The SECuRE trial is studying a new treatment for men with a specific type of advanced prostate cancer called metastatic castrate-resistant prostate cancer (mCRPC). This trial aims to evaluate the s...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, Baltimore, Maryland, United States +8 more

HTL0039732 in Participants With Advanced Solid Tumours

NCT ID: NCT05944237

This clinical trial is studying a new drug called HTL0039732 to see how it works for people with advanced solid tumors, which are types of cancer that form in various organs, like the prostate, sto...

Recruiting

Phase: PHASE1 Type: interventional Locations: London, , United Kingdom, Cambridge, , United Kingdom +3 more

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

NCT ID: NCT04104776

This clinical trial is investigating a new treatment called CPI-0209 for patients with advanced solid tumors and lymphomas, including various types of cancer such as lymphoma and mesothelioma. CPI-...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States +92 more

Study of 225Ac-PSMA-617 in Men With PSMA-positive Prostate Cancer

NCT ID: NCT04597411

This clinical trial is studying a new treatment called 225Ac-PSMA-617 for men with a specific type of prostate cancer known as PSMA-positive prostate cancer. The trial aims to find out how safe thi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Darlinghurst, , Australia, Pretoria, , South Africa

Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer

NCT ID: NCT06190899

This clinical trial is studying a new treatment approach for men with metastatic castration-resistant prostate cancer (mCRPC). The researchers want to find out if combining two drugs, gedatolisib a...

Recruiting

Phase: PHASE1 Type: interventional Locations: Detroit, Michigan, United States, Clermont Ferrand, , France +12 more

Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer

NCT ID: NCT05743621

This clinical trial is studying a new treatment for men with advanced prostate cancer that has not improved with previous therapies. The researchers want to find out if combining two medications—En...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

NCT ID: NCT06706921

This clinical trial is studying how a specific imaging test called 18F-Fluciclovine PET/CT can help predict how well a treatment called Lutetium-PSMA-617 therapy works for men with advanced prostat...

Recruiting

Phase: PHASE4 Type: interventional Locations: Los Angeles, California, United States

Phase II Randomised Controlled Trial of Patient-specific Adaptive vs. Continuous Abiraterone or eNZalutamide in mCRPC

NCT ID: NCT05393791

This clinical trial is studying two different ways to use hormone treatments, abiraterone (Zytiga®) and enzalutamide (Xtandi®), for men with advanced prostate cancer that no longer responds to horm...

Recruiting

Phase: PHASE2 Type: interventional Locations: Adelaide, South Australia, Australia, Groningen, , Netherlands +17 more

Actium-225-Prostate Specific Membrane Antigen Imaging & Therapy

NCT ID: NCT05902247

The Actium-225 trial is studying a new treatment for men with advanced prostate cancer that has not responded to standard hormone therapies. This treatment uses a special drug called 225Ac-PSMA I&T...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rotterdam, Zuid Holland, Netherlands, Rotterdam, Zuid Holland, Netherlands

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