Clinical Trials for Recurrent Head and Neck Squamous Cell Carcinoma

Find clinical trials for recurrent head and neck squamous cell carcinoma. Discover research opportunities and treatment options in your area.

19 Active Trials Found

Showing 19 trials on this page

Page 1 of 1

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

NCT ID: NCT06589804

This clinical trial is studying whether adding a medication called cetuximab to the standard treatment pembrolizumab can better help patients with certain types of head and neck cancers that have r...

Recruiting

Phase: PHASE3 Type: interventional Locations: Saint Louis, Missouri, United States, Flint, Michigan, United States +95 more

Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC

NCT ID: NCT05726370

This clinical trial is investigating a new treatment approach for patients with recurrent squamous cell carcinoma of the head and neck (HNSCC) who can still have surgery. The study is testing wheth...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Re-Radiochemotherapy and Pembrolizumab vs. Immuno(Chemo)Therapy for Locoregionally Recurrent PD-L1 Positive (CPS≥1) HNSCC

NCT ID: NCT07026474

This clinical trial is studying a new treatment approach for people with head and neck cancer that has come back in the same area after previous treatment. Specifically, it looks at whether adding ...

Not yet recruiting

Phase: PHASE3 Type: interventional Locations: Regensburg, , Germany, Chemnitz, , Germany +16 more

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

NCT ID: NCT06788990

The FORTIFI-HN01 clinical trial is studying a new treatment called ficerafusp alfa, which targets two specific proteins in the body, in combination with another medication called pembrolizumab. Thi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Charleston, South Carolina, United States, Nashville, Tennessee, United States +24 more

A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

NCT ID: NCT06699212

This clinical trial is studying a new treatment approach for patients with recurrent squamous cell carcinoma of the head and neck, which is a type of cancer that affects the mouth, throat, or nose....

Recruiting

Phase: PHASE3 Type: interventional Locations: Providence, Rhode Island, United States, Sioux Falls, South Dakota, United States +20 more

PD-L1 t-haNK, N-803 IL-15sa and Cetuximab for Recurrent, Metastatic HNSCC

NCT ID: NCT06239220

This clinical trial is exploring a new treatment combination for patients with advanced head and neck cancer that has come back or spread to other parts of the body. The study is testing three ther...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

NCT ID: NCT04671667

This clinical trial is exploring whether a drug called pembrolizumab, which helps the immune system fight cancer, is more effective on its own compared to the standard treatment of chemotherapy and...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States, New Haven, Connecticut, United States +169 more

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

NCT ID: NCT06980038

This clinical trial is exploring whether a combination of two treatments, cemiplimab (REGN2810) and CDX-1140, is more effective than using cemiplimab alone for patients with advanced head and neck ...

Not yet recruiting

Phase: PHASE2 Type: interventional

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

NCT ID: NCT06265285

This clinical trial is exploring whether giving a cancer treatment called nivolumab at home is just as safe and effective as receiving it in a clinic. By allowing patients to receive treatment in t...

Recruiting

Phase: PHASE2 Type: interventional Locations: Jacksonville, Florida, United States

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

NCT ID: NCT06868433

This clinical trial is testing a new treatment approach for patients with certain types of head and neck cancer that has either returned after treatment or spread to other parts of the body. The st...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Atlanta, Georgia, United States, Atlanta, Georgia, United States

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

NCT ID: NCT06064877

This clinical trial is investigating the effectiveness and safety of a new treatment called ficlatuzumab when combined with cetuximab for patients with recurrent or metastatic head and neck cancer ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Baltimore, Maryland, United States, Bronx, New York, United States +110 more

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

NCT ID: NCT06662058

This clinical trial is looking at how offering hearing tests close to home or through remote options can help monitor hearing loss in patients with certain types of head and neck cancers who are re...

Recruiting

Phase: NA Type: interventional Locations: Atlanta, Georgia, United States

Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

NCT ID: NCT04375384

This clinical trial is studying the use of a drug called Cetuximab to treat patients with head and neck squamous cell carcinoma that has returned or spread after previous treatment with immunothera...

Recruiting

Phase: PHASE2 Type: interventional Locations: Winston Salem, North Carolina, United States

Ramucirumab and Pembrolizumab vs Pembrolizumab Monotherapy in PD-L1 Positive Head and Neck Squamous-Cell Carcinoma

NCT ID: NCT05980000

This clinical trial is studying the combination of two drugs, ramucirumab and pembrolizumab, to see if they work better together than pembrolizumab alone for patients with certain types of head and...

Recruiting

Phase: PHASE2 Type: interventional Locations: Saint Louis, Missouri, United States

Lovastatin and Pembrolizumab for the Treatment of Patients with Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

NCT ID: NCT06636734

The LAPP Trial is a research study looking at how well two medications, lovastatin and pembrolizumab, work together to treat patients with certain types of head and neck cancer that have either ret...

Recruiting

Phase: PHASE2 Type: interventional Locations: Atlanta, Georgia, United States

Evaluating 111In Panitumumab for Nodal Staging in Head and Neck Cancer

NCT ID: NCT05901545

This clinical trial is investigating a new method to help doctors identify the first lymph nodes that cancer may have spread to in patients with head and neck cancer. The study uses a special radio...

Recruiting

Phase: PHASE1 Type: interventional Locations: Nashville, Tennessee, United States

Evaluating the Use of Dual Imaging Techniques for Detection of Disease in Patients with Head and Neck Cancer

NCT ID: NCT05945875

This clinical trial is studying a new way to detect head and neck cancer using two advanced imaging techniques. The goal is to find out if combining these methods—one that uses a special radioactiv...

Recruiting

Phase: PHASE1 Type: interventional Locations: Nashville, Tennessee, United States

Establishment of a Microfluidic Based Liquid Biopsy Platform for Recurrent/Metastatic Head and Neck Cancers Prognostication Using NK Cell IFN-γ Expression and CTM Correlation With DS-SACA Chip

NCT ID: NCT06678724

This clinical trial is focused on understanding how certain blood components can help predict the outcomes for patients with recurrent or metastatic head and neck cancers, specifically squamous cel...

Not yet recruiting

Type: observational Locations: Zhubei City, , Taiwan, Zhubei City, Hsinchu County, Taiwan

Identification of Pattern and Factors Affecting Recurrence in Head and Neck Carcinoma

NCT ID: NCT06465030

This clinical trial is looking into how and why head and neck cancer sometimes comes back after treatment. Researchers will review past treatment experiences to find out how often the cancer return...

Recruiting

Type: observational Locations: Sohag, , Egypt, Sohag, , Egypt

Related Conditions

Breast Cancer View clinical trials → Stroke View clinical trials → Obesity View clinical trials → Cancer View clinical trials → Healthy View clinical trials → Prostate Cancer View clinical trials →

Search All Trials Browse All Conditions