Clinical Trials for Refractory Acute Myeloid Leukemia

Find clinical trials for refractory acute myeloid leukemia. Discover research opportunities and treatment options in your area.

45 Active Trials Found

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Liposome-encapsulated Daunorubicin-Cytarabine and Venetoclax in Treating Participants With Relapsed, Refractory or Untreated Acute Myeloid Leukemia

NCT ID: NCT03629171

This clinical trial is exploring a new treatment for adults with acute myeloid leukemia (AML), a type of blood cancer that can come back after treatment, does not respond to previous therapies, or ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

NCT ID: NCT06871410

This clinical trial is studying a new treatment for patients with acute myeloid leukemia (AML) that has either come back after treatment or did not respond to previous therapies. Researchers are te...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Buffalo, New York, United States

A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT ID: NCT06763341

This clinical trial is studying a new treatment for patients with acute myeloid leukemia (AML) that has either returned after treatment (relapsed) or has not responded to previous therapies (refrac...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

NCT ID: NCT03128034

This clinical trial is looking at a new treatment called 211^astatine-BC8-B10 for patients with certain types of blood cancers, including high-risk acute myeloid leukemia (AML), acute lymphoblastic...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

MiRisten for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

NCT ID: NCT07025564

This clinical trial is studying a new drug called miRisten to see if it is safe and what dose works best for treating adults with a type of blood cancer called acute myeloid leukemia (AML) that has...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States

CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

NCT ID: NCT04493164

This clinical trial is studying the combination of two treatments, CPX-351 and ivosidenib, to see how effective they are in helping patients with a specific type of blood cancer called acute myeloi...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

NCT ID: NCT04047641

This clinical trial is exploring how well a combination of four medications—cladribine, idarubicin, cytarabine, and quizartinib—works to treat patients with specific types of blood cancers, includi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

NCT ID: NCT06484062

This clinical trial is studying a new anti-cancer drug called cirtuvivint, both by itself and in combination with another treatment known as ASTX727. The goal is to see if these treatments can help...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

NCT ID: NCT07012044

This clinical trial is studying a new treatment option for children with high-risk acute myeloid leukemia (AML), especially those whose cancer has returned or hasn't responded to previous treatment...

Not yet recruiting

Phase: PHASE1 Type: interventional

Clinical Trial of WBC100 Capsule in Relapsed/Refractory Acute Myeloid Leukemia

NCT ID: NCT07014449

This clinical trial is studying a new treatment called WBC100 capsules for patients with relapsed or refractory acute myeloid leukemia (R/R AML), which means their cancer has returned or has not re...

Recruiting

Phase: PHASE1 Type: interventional Locations: Hangzhou, Zhejiang, China

Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

NCT ID: NCT04128748

This clinical trial is investigating a new treatment for acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS), using a combination of two medications: CPX-351 and quizartinib. ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

NCT ID: NCT03670966

This clinical trial is studying a new treatment approach for patients with high-risk acute leukemia or myelodysplastic syndrome, especially those whose disease has come back or is not responding to...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

NCT ID: NCT04774393

This clinical trial is studying a combination of new treatments for patients with acute myeloid leukemia (AML) that has either returned after treatment or did not respond to previous therapies. The...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

NCT ID: NCT06501196

This clinical trial is studying a new medication called BH-30236 for patients with relapsed or refractory acute myelogenous leukemia (AML) and higher-risk myelodysplastic syndrome (HR-MDS). The tri...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Duarte, California, United States +8 more

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

NCT ID: NCT03661307

This clinical trial is studying a combination of three medications—quizartinib, decitabine, and venetoclax—to see how well they work in treating patients with acute myeloid leukemia (AML) or high-r...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid Leukemia

NCT ID: NCT06017258

This clinical trial is investigating a new treatment called CD371-YSNVZ-IL18 CAR T cells for people with a type of blood cancer known as Acute Myeloid Leukemia (AML), specifically for those whose c...

Recruiting

Phase: PHASE1 Type: interventional Locations: Middletown, New Jersey, United States, Montvale, New Jersey, United States +5 more

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

NCT ID: NCT03630991

This clinical trial is studying two potential treatments, edetate calcium disodium and succimer, for patients with certain types of blood cancers, specifically acute myeloid leukemia (AML) or myelo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

NCT ID: NCT03214562

This clinical trial is investigating the use of a new treatment combination for patients with acute myeloid leukemia (AML) who are either newly diagnosed or whose cancer has returned or is not resp...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

NCT ID: NCT02115295

This clinical trial is investigating a combination of four chemotherapy drugs—cladribine, idarubicin, cytarabine, and venetoclax—to see how well they work in treating patients with certain types of...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

NCT ID: NCT04797767

This clinical trial is studying a new treatment approach for patients with acute myeloid leukemia (AML) and high-grade myeloid neoplasms. Researchers are testing a combination of a medication calle...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seattle, Washington, United States

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