Clinical Trials for Secondary Acute Myeloid Leukemia

Find clinical trials for secondary acute myeloid leukemia. Discover research opportunities and treatment options in your area.

12 Active Trials Found

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A Proof of Concept Pilot Study of the Addition of Venetoclax to Standard Remission Induction Chemotherapy Fludarabine or Cladrabine, Cytarabine, and Granulocyte Colony Stimulating Factor (G-CSF) (FLAG or CLAG) for Frontline Therapy of Secondary Acute Myeloid Leukemia

NCT ID: NCT05780879

This clinical trial is looking at a new treatment approach for patients with secondary acute myeloid leukemia (sAML), a type of blood cancer that occurs after other blood disorders or treatments. T...

Recruiting

Phase: PHASE2 Type: interventional Locations: Ann Arbor, Michigan, United States

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

NCT ID: NCT05554419

The ERASE Study is a clinical trial designed to explore different combinations of treatments for patients with persistent low-level Acute Myeloid Leukemia (AML) after their initial therapy. The tri...

Not yet recruiting

Phase: PHASE2 Type: interventional

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

NCT ID: NCT03630991

This clinical trial is studying two potential treatments, edetate calcium disodium and succimer, for patients with certain types of blood cancers, specifically acute myeloid leukemia (AML) or myelo...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

NCT ID: NCT02115295

This clinical trial is investigating a combination of four chemotherapy drugs—cladribine, idarubicin, cytarabine, and venetoclax—to see how well they work in treating patients with certain types of...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Personalized NK Cell Therapy in CBT

NCT ID: NCT02727803

This clinical trial is looking at a new treatment called personalized natural killer (NK) cell therapy for patients with certain types of blood cancers, including leukemia, lymphoma, and myelodyspl...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

NCT ID: NCT03494569

This clinical trial is exploring a new treatment approach for patients with high-risk acute leukemia or myelodysplastic syndrome. The treatment combines total marrow and lymphoid irradiation with t...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States

CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia

NCT ID: NCT05672147

This clinical trial is exploring a new treatment called CD33-CAR T-cell therapy for adults with acute myeloid leukemia (AML) that has returned after treatment or hasn’t responded to therapy. In thi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States

CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

NCT ID: NCT04269213

This clinical trial, called CPX-351, is looking at a new treatment option for patients under 60 years old who have secondary acute myeloid leukemia (AML). This type of leukemia can develop from oth...

Recruiting

Phase: PHASE2 Type: interventional Locations: Buffalo, New York, United States, Omaha, Nebraska, United States +2 more

90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome

NCT ID: NCT05139004

This clinical trial is exploring a new treatment approach for patients with high-risk acute leukemia or myelodysplastic syndrome, which are serious blood disorders. The study is testing a combinati...

Recruiting

Phase: PHASE1 Type: interventional Locations: Duarte, California, United States

Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML

NCT ID: NCT05807932

This clinical trial is studying a new treatment approach for patients with certain blood cancers, specifically myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML), or secondary ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Frankfurt, , Germany, Köln, , Germany +4 more

Unrelated Umbilical Cord Blood Stem Cell Combined With Azacitidine Based Treatment for Advanced MDS,CMML-2 and sAML

NCT ID: NCT05584761

This clinical trial is looking at a new treatment approach for patients with advanced blood disorders, specifically myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML-2), and se...

Recruiting

Phase: PHASE1 Type: interventional Locations: Nanjing, Jiangsu, China

Clinical Study Protocol of Venetoclax Combined With Azacitidine and Harringtonine in the Treatment of sAML

NCT ID: NCT05513131

This clinical trial is studying a combination treatment involving three medications—Venetoclax, Azacitidine, and Harringtonine—aimed at helping patients with secondary acute myeloid leukemia (sAML)...

Recruiting

Phase: PHASE2 Type: interventional Locations: Nanjing, Jiangsu, China

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