Clinical Trials for Stage IV Prostate Cancer AJCC v8

Find clinical trials for stage iv prostate cancer ajcc v8. Discover research opportunities and treatment options in your area.

19 Active Trials Found

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Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

NCT ID: NCT04550494

This clinical trial is studying a medication called talazoparib to see how well it works for patients with advanced cancers that have spread in the body and have specific changes in their DNA repai...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bethesda, Maryland, United States, Oklahoma City, Oklahoma, United States +2 more

Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

NCT ID: NCT05691465

This clinical trial is investigating a new treatment called Lutetium Lu 177 dotatate for men with metastatic prostate cancer that has neuroendocrine differentiation, meaning the cancer cells have c...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States, Duarte, California, United States +13 more

Extremely Hypofractionated Intensity Modulated Stereotactic Body Radiotherapy for the Treatment of Prostate Cancer With Rising PSA After Radical Prostatectomy

NCT ID: NCT04915508

This clinical trial is exploring a new way to treat prostate cancer in men whose prostate-specific antigen (PSA) levels are rising after they have had surgery to remove their prostate (radical pros...

Recruiting

Phase: PHASE2 Type: interventional Locations: Los Angeles, California, United States

A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

NCT ID: NCT06630325

The SMMART-ACT clinical trial is exploring a new way to treat patients with advanced cancers, such as sarcoma, breast, prostate, ovarian, and pancreatic cancer. This study uses a personalized appro...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Portland, Oregon, United States, Portland, Oregon, United States

Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA Trial

NCT ID: NCT07025369

This clinical trial is studying whether a short treatment with a medicine called relugolix can help improve imaging tests used to find prostate cancer in men with high-risk prostate cancer. Relugol...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Scottsdale, Arizona, United States

SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma

NCT ID: NCT06205316

This clinical trial is comparing two types of radiation therapy for men with prostate cancer that has either come back after treatment or spread to a few other places in the body. The trial is spec...

Recruiting

Phase: PHASE3 Type: interventional Locations: Scottsdale, Arizona, United States, Rochester, Minnesota, United States +4 more

Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

NCT ID: NCT05113537

This clinical trial is studying a new treatment approach for men with advanced prostate cancer that has spread to other parts of the body and is no longer responding to standard hormone therapy. Th...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Francisco, California, United States

Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network

NCT ID: NCT05627219

The EXPAND Network trial is studying how a group of trained peer genetic coaches can help African American men with metastatic prostate cancer get better access to genetic testing. Genetic testing ...

Recruiting

Type: observational Locations: Philadelphia, Pennsylvania, United States

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

NCT ID: NCT04693377

The CROME Trial is studying a new treatment approach for patients suffering from painful bone metastases, which occur when cancer spreads to the bones. The trial compares two methods: one combines ...

Recruiting

Phase: NA Type: interventional Locations: Houston, Texas, United States

ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

NCT ID: NCT04471974

This clinical trial, titled ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer, is exploring how effective a combination of three treatme...

Recruiting

Phase: PHASE2 Type: interventional Locations: Ann Arbor, Michigan, United States, San Francisco, California, United States +1 more

Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer, The AtezoCab Trial

NCT ID: NCT05168618

The AtezoCab Trial is a clinical study investigating the effectiveness of two drugs, cabozantinib and atezolizumab, in treating men with advanced prostate cancer that has continued to grow despite ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Salt Lake City, Utah, United States

Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients

NCT ID: NCT05045066

This clinical trial is studying how common low levels of vitamin D are among African American men who have had prostate cancer, whether it was localized (not spread) or metastatic (spread to other ...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Scottsdale, Arizona, United States, Scottsdale, Arizona, United States +1 more

Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation

NCT ID: NCT05487846

This clinical trial is looking at how having a trained peer navigator can help African American men with metastatic prostate cancer, which means their cancer has spread beyond the prostate. The tri...

Not yet recruiting

Phase: NA Type: interventional

Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer

NCT ID: NCT04734730

This clinical trial is looking at a new treatment approach for men with castration-sensitive prostate cancer, which is cancer that still responds to hormone therapy. Researchers are studying the co...

Recruiting

Phase: PHASE2 Type: interventional Locations: Duarte, California, United States

Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer

NCT ID: NCT06173362

This clinical trial is exploring how well two different treatments work for men with advanced prostate cancer, which is cancer that has spread from its original site to other parts of the body. The...

Recruiting

Phase: PHASE2 Type: interventional Locations: Sacramento, California, United States

Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

NCT ID: NCT05869682

This clinical trial is investigating whether bright white light therapy can help reduce feelings of tiredness and depression in men with advanced prostate cancer who are receiving specific treatmen...

Recruiting

Phase: PHASE2 Type: interventional Locations: Duarte, California, United States

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

NCT ID: NCT03678025

This clinical trial is exploring how effective standard systemic therapy is when combined with additional treatments, like prostate removal surgery or radiation therapy, for men with metastatic pro...

Recruiting

Phase: PHASE3 Type: interventional Locations: Chicago, Illinois, United States, New Haven, Connecticut, United States +343 more

Relugolix in Combination With Radiation Therapy for Treating Patients With High Risk Prostate Cancer

NCT ID: NCT06129851

This clinical trial is studying the use of a medication called relugolix combined with radiation therapy to treat men with high-risk prostate cancer. Prostate cancer can grow more quickly when ther...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Kansas City, Kansas, United States

Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring

NCT ID: NCT05054296

This clinical trial is looking at how a special exercise program and using a Fitbit to track activity can help prostate cancer patients manage their heart health and a condition called metabolic sy...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

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