Clinical Trials for TNBC - Triple-Negative Breast Cancer

Find clinical trials for tnbc - triple-negative breast cancer. Discover research opportunities and treatment options in your area.

32 Active Trials Found

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A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

NCT ID: NCT06257264

This clinical trial is studying a new treatment called BG-68501 for patients with advanced-stage tumors, including certain types of breast cancer, lung cancer, ovarian cancer, and others. The main ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States, Brisbane, Queensland, Australia +44 more

Intratumoral INT230-6 Followed by Neoadjuvant Immuno-chemotherapy in Patients With Early TNBC. INVINCIBLE-4-SAKK

NCT ID: NCT06358573

The INVINCIBLE-4-SAKK clinical trial is studying a new treatment approach for patients with early-stage triple-negative breast cancer (TNBC), a type of breast cancer known for being more aggressive...

Recruiting

Phase: PHASE2 Type: interventional Locations: St. Gallen, , Switzerland, Chur, , Switzerland +11 more

SC-101 in Subjects With Advanced NECTIN4-Amplified Cancers

NCT ID: NCT07080619

This clinical trial is studying a new treatment called SC-101 for people with advanced cancers that have a specific change in their genes called NECTIN4 amplification. The trial focuses on certain ...

Not yet recruiting

Phase: PHASE2 Type: interventional

Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early-Stage Triple Negative Breast Cancer

NCT ID: NCT07017673

This clinical trial is studying a new treatment for patients with early-stage triple-negative breast cancer (TNBC), a type of breast cancer that does not respond to certain hormones. The trial will...

Recruiting

Phase: PHASE2 Type: interventional Locations: Los Angeles, California, United States, Los Angeles, California, United States +2 more

PSMA-PET/CT to Assess the Expression of Specific Membrane Antigen (PSMA) in Patients With Progressive Triple-negative Breast Cancer.

NCT ID: NCT06059469

This clinical trial is looking at a special type of imaging called PSMA-PET/CT to understand how a specific protein, known as PSMA, behaves in women with a type of breast cancer called triple-negat...

Recruiting

Phase: PHASE2 Type: interventional Locations: Brussels, , Belgium

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

NCT ID: NCT01042379

The I-SPY Trial is a research study aimed at finding out which new medications work best for different types of breast cancer. The goal is to personalize treatment by looking at how tumors respond ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States, Los Angeles, California, United States +35 more

A Multi-center, Randomized, Open-label, Phase III Study Comparing PD-1 Inhibitor Combined With Antivascular Therapy and Anthracycline/Taxane-based Adjuvant Chemotherapy Versus Anthracycline/Taxane-based Adjuvant Chemotherapy Alone in Patients With Operable Triple-negative Breast Cancer

NCT ID: NCT05862064

This clinical trial is investigating a new treatment approach for women with operable triple-negative breast cancer (TNBC), a type of breast cancer that does not respond to certain hormones and tre...

Recruiting

Phase: PHASE3 Type: interventional Locations: Shanghai, Shanghai, China

Role of the Immune Environment in Response to Therapy in Breast Cancer

NCT ID: NCT05396612

This clinical trial is looking at how the immune system affects the response to treatment in different types of breast cancer. Researchers will compare tissue samples from women with estrogen recep...

Recruiting

Type: observational Locations: Philadelphia, Pennsylvania, United States

Trop-2 Targeted PET Probes in Advanced TNBC

NCT ID: NCT07046455

This clinical trial is studying a new way to see how well a specific treatment works for people with advanced triple-negative breast cancer (TNBC), a type of breast cancer that can be harder to tre...

Recruiting

Phase: NA Type: interventional Locations: Beijing, Beijing, China

SHR-A2102 Combined With Adebrelimab as Neoadjuvant Therapy for Early Triple-Negative Breast Cancer

NCT ID: NCT06819319

This clinical trial is studying a new treatment approach for early-stage triple-negative breast cancer (TNBC), which is a type of breast cancer that does not have three common markers that are ofte...

Not yet recruiting

Phase: PHASE2 Type: interventional

A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer

NCT ID: NCT06568692

This clinical trial is testing a new treatment combination for patients with advanced or metastatic breast cancer, specifically those with triple-negative breast cancer or hormone receptor-positive...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States, New Brunswick, New Jersey, United States +11 more

ASTRAEA: ReinvigorAting ReSponse To ImmunotheRApy in MEtAstatic TNBC With Combination Myeloid Inhibition and Radiation

NCT ID: NCT07015853

The ASTRAEA trial is a study looking at a new treatment approach for patients with advanced triple-negative breast cancer (TNBC), a type of breast cancer that does not respond to some common treatm...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Los Angeles, California, United States

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

NCT ID: NCT06657222

This clinical trial is testing a new drug called TUB-030 to see if it can effectively treat advanced solid tumors, including types like head and neck cancer, lung cancer, and triple-negative breast...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Cleveland, Ohio, United States +6 more

Study of AVZO-021 in Patients With Advanced Solid Tumors

NCT ID: NCT05867251

This clinical trial is studying a new oral medication called AVZO-021, which is designed to treat patients with advanced solid tumors. The main goals of the study are to understand how safe the med...

Recruiting

Phase: PHASE1 Type: interventional Locations: Tampa, Florida, United States, Sarasota, Florida, United States +8 more

Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)

NCT ID: NCT05660083

This clinical trial is investigating a new treatment approach for patients with a specific type of breast cancer called HER2-negative metaplastic breast cancer, particularly those whose cancer has ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States, Houston, Texas, United States +1 more

A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer

NCT ID: NCT04683679

This clinical trial is investigating whether adding two medications, pembrolizumab and olaparib, to standard radiation therapy can provide a safer and more effective treatment for women with advanc...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Basking Ridge, New Jersey, United States +5 more

NearWave Optical Molecular Monitoring

NCT ID: NCT06744465

The NearWave Optical Molecular Monitoring trial is studying a new system to help doctors track how well breast cancer patients are responding to treatment. Specifically, it aims to see if this tech...

Recruiting

Phase: NA Type: interventional Locations: Indianapolis, Indiana, United States

Immunotherapy-related CRP Kinetics in Early and Metastatic Triple-negative Breast Cancer

NCT ID: NCT05914961

This clinical trial, called ICK-breast, is studying how changes in a blood marker called CRP (C-reactive protein) relate to treatment outcomes for women with triple-negative breast cancer (TNBC). T...

Recruiting

Type: observational Locations: Tuebingen, , Germany

BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

NCT ID: NCT05768932

This clinical trial is exploring the use of a new treatment called BAL0891 for patients with advanced solid tumors, including triple-negative breast cancer (TNBC) and gastric cancer. The study aims...

Recruiting

Phase: PHASE1 Type: interventional Locations: Portland, Oregon, United States, Bronx, New York, United States +14 more

Neoadjuvant Dupilumab, Pembrolizumab, Paclitaxel, and Carboplatin in Locally Advanced Triple Negative Breast Cancer

NCT ID: NCT06637306

This clinical trial is studying a new treatment approach for patients with locally advanced triple-negative breast cancer (TNBC), a type of breast cancer that does not have certain hormones that ca...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: New York, New York, United States

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