Clinical Trials for TNBC - Triple-Negative Breast Cancer

Find clinical trials for tnbc - triple-negative breast cancer. Discover research opportunities and treatment options in your area.

31 Active Trials Found

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SHR-A2102 Combined With Adebrelimab as Neoadjuvant Therapy for Early Triple-Negative Breast Cancer

NCT ID: NCT06819319

This clinical trial is studying a new treatment approach for early-stage triple-negative breast cancer (TNBC), which is a type of breast cancer that does not have three common markers that are ofte...

Not yet recruiting

Phase: PHASE2 Type: interventional

A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer

NCT ID: NCT06568692

This clinical trial is testing a new treatment combination for patients with advanced or metastatic breast cancer, specifically those with triple-negative breast cancer or hormone receptor-positive...

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States, New Brunswick, New Jersey, United States +11 more

ASTRAEA: ReinvigorAting ReSponse To ImmunotheRApy in MEtAstatic TNBC With Combination Myeloid Inhibition and Radiation

NCT ID: NCT07015853

The ASTRAEA trial is a study looking at a new treatment approach for patients with advanced triple-negative breast cancer (TNBC), a type of breast cancer that does not respond to some common treatm...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Los Angeles, California, United States

Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early-Stage Triple Negative Breast Cancer

NCT ID: NCT07017673

This clinical trial is studying a new treatment for patients with early-stage triple-negative breast cancer (TNBC), a type of breast cancer that does not respond to certain hormones. The trial will...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Los Angeles, California, United States, Los Angeles, California, United States +2 more

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

NCT ID: NCT06657222

This clinical trial is testing a new drug called TUB-030 to see if it can effectively treat advanced solid tumors, including types like head and neck cancer, lung cancer, and triple-negative breast...

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Cleveland, Ohio, United States +6 more

Study of AVZO-021 in Patients With Advanced Solid Tumors

NCT ID: NCT05867251

This clinical trial is studying a new oral medication called AVZO-021, which is designed to treat patients with advanced solid tumors. The main goals of the study are to understand how safe the med...

Phase: PHASE1 Type: interventional Locations: Tampa, Florida, United States, Sarasota, Florida, United States +8 more

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

NCT ID: NCT06257264

This clinical trial is studying a new treatment called BG-68501 for patients with advanced-stage tumors, including certain types of breast cancer, lung cancer, ovarian cancer, and others. The main ...

Phase: PHASE1 Type: interventional Locations: Saint Louis, Missouri, United States, Brisbane, Queensland, Australia +43 more

Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)

NCT ID: NCT05660083

This clinical trial is investigating a new treatment approach for patients with a specific type of breast cancer called HER2-negative metaplastic breast cancer, particularly those whose cancer has ...

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States, Houston, Texas, United States +1 more

A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer

NCT ID: NCT04683679

This clinical trial is investigating whether adding two medications, pembrolizumab and olaparib, to standard radiation therapy can provide a safer and more effective treatment for women with advanc...

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Basking Ridge, New Jersey, United States +5 more

NearWave Optical Molecular Monitoring

NCT ID: NCT06744465

The NearWave Optical Molecular Monitoring trial is studying a new system to help doctors track how well breast cancer patients are responding to treatment. Specifically, it aims to see if this tech...

Phase: NA Type: interventional Locations: Indianapolis, Indiana, United States

Immunotherapy-related CRP Kinetics in Early and Metastatic Triple-negative Breast Cancer

NCT ID: NCT05914961

This clinical trial, called ICK-breast, is studying how changes in a blood marker called CRP (C-reactive protein) relate to treatment outcomes for women with triple-negative breast cancer (TNBC). T...

Type: observational Locations: Tuebingen, , Germany

BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

NCT ID: NCT05768932

This clinical trial is exploring the use of a new treatment called BAL0891 for patients with advanced solid tumors, including triple-negative breast cancer (TNBC) and gastric cancer. The study aims...

Phase: PHASE1 Type: interventional Locations: Portland, Oregon, United States, Bronx, New York, United States +14 more

Neoadjuvant Dupilumab, Pembrolizumab, Paclitaxel, and Carboplatin in Locally Advanced Triple Negative Breast Cancer

NCT ID: NCT06637306

This clinical trial is studying a new treatment approach for patients with locally advanced triple-negative breast cancer (TNBC), a type of breast cancer that does not have certain hormones that ca...

Phase: EARLY_PHASE1 Type: interventional Locations: New York, New York, United States

Intratumoral INT230-6 Followed by Neoadjuvant Immuno-chemotherapy in Patients With Early TNBC. INVINCIBLE-4-SAKK

NCT ID: NCT06358573

The INVINCIBLE-4-SAKK clinical trial is studying a new treatment approach for patients with early-stage triple-negative breast cancer (TNBC), a type of breast cancer known for being more aggressive...

Phase: PHASE2 Type: interventional Locations: St. Gallen, , Switzerland, Chur, , Switzerland +10 more

Study of LP-184 in Patients With Advanced Solid Tumors

NCT ID: NCT05933265

This clinical trial is investigating a new treatment called LP-184 for patients with advanced solid tumors, which are cancers that have spread and are not responding to standard therapies. The main...

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Indianapolis, Indiana, United States +8 more

Real-world Patient-reported Outcome of Sacituzumab Govitecan in Chinese Metastatic Triple-negative Breast Cancer

NCT ID: NCT06798506

This clinical trial is studying how a treatment called sacituzumab govitecan affects the quality of life for women with metastatic triple-negative breast cancer (TNBC) in China. It aims to understa...

Not yet recruiting

Type: observational Locations: Shanghai, Shanghai, China

CtDNA Based MRD Testing for NAC Monitoring in TNBC

NCT ID: NCT06230185

This clinical trial is studying a new way to monitor treatment in women with triple-negative breast cancer (TNBC) who are receiving chemotherapy before surgery, known as neoadjuvant chemotherapy (N...

Type: observational Locations: New Orleans, Louisiana, United States, Spokane, Washington, United States +13 more

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

NCT ID: NCT01042379

The I-SPY Trial is a research study aimed at finding out which new medications work best for different types of breast cancer. The goal is to personalize treatment by looking at how tumors respond ...

Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States, Los Angeles, California, United States +35 more

SBRT Combined With PD-1 Inhibitor and Chemotherapy in Early-stage TNBC

NCT ID: NCT06627712

This clinical trial is investigating a new treatment approach for women with early-stage triple-negative breast cancer (TNBC), a type of breast cancer that can be harder to treat. The study is look...

Not yet recruiting

Phase: PHASE3 Type: interventional

LM-108 in Combination With PD-1 Based Treatment for Patients With Recurrent or Metastatic Triple - Negative Breast Cancer

NCT ID: NCT06387628

This clinical trial is studying a new treatment combining LM-108 with toripalimab and either nab-paclitaxel or eribulin for patients with recurrent or metastatic triple-negative breast cancer (TNBC...

Phase: PHASE2 Type: interventional Locations: Shanghai, Shanghai, China

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