Clinical Trials for TP53

Find clinical trials for tp53. Discover research opportunities and treatment options in your area.

6 Active Trials Found

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ALPINE: Maintenance Letrozole/Abemaciclib vs Pembrolizumab

NCT ID: NCT06366347

The ALPINE clinical trial is studying two different maintenance treatments for patients with endometrial cancer, specifically looking at how well they work after initial chemotherapy. Currently, ma...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +6 more

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

NCT ID: NCT05735717

This clinical trial, titled "MT2021-08 T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies," is exploring a new treatment approach for patients with certain blood cancer...

Recruiting

Phase: PHASE2 Type: interventional Locations: Minneapolis, Minnesota, United States

Phase I/II Clinical Trial of Proteasome Inhibitor in Combination With CPX-351 for the Treatment of Newly-Diagnosed TP53-mutated Acute Myeloid Leukemia (AML)

NCT ID: NCT07008638

This clinical trial is studying a new treatment approach for adults with a specific type of leukemia called acute myeloid leukemia (AML) that has a mutation in a gene known as TP53. The researchers...

Recruiting

Phase: PHASE1 Type: interventional Locations: Minneapolis, Minnesota, United States

AZA Combined With RCHOP in P53-mutated DLBCL.

NCT ID: NCT06158399

This clinical trial is studying a new treatment approach for patients with a specific type of cancer called Diffuse Large B-cell Lymphoma (DLBCL), which is often associated with a mutation in a gen...

Recruiting

Phase: PHASE2 Type: interventional Locations: Xiamen, Fujian, China

Safety and Efficacy of Aumolertinib Combined With Anlotinib as 1st Line Treatment in Advanced Lung Cancer EGFR Mutation With TP53 Co-Mutation

NCT ID: NCT05778149

This clinical trial is investigating the safety and effectiveness of two medications, Aumolertinib and Anlotinib, used together as a first-line treatment for patients with advanced non-small cell l...

Not yet recruiting

Phase: PHASE2 Type: interventional

Venetoclax and Decitabin Based Conditioning Regimen Followed With Post-HSCT Decitabin Maintenance Therapy in TP53 Mutant AML/MDS Patients

NCT ID: NCT05528354

This clinical trial is investigating a new treatment approach for patients with specific blood cancers called Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS) that have a mutation in...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Hangzhou, Zhejiang, China

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