Clinical Trials for Triple Negative Breast Cancer

Find clinical trials for triple negative breast cancer. Discover research opportunities and treatment options in your area.

160 Active Trials Found

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Genomically Guided Radiation Therapy in the Management of Triple Negative Breast Cancer

NCT ID: NCT05528133

This clinical trial is studying a new approach called genomically guided radiation therapy for people with triple negative breast cancer, which is a type of cancer that does not have certain hormon...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States, Clearwater, Florida, United States

Phase II Trial Evaluating the Safety and Efficacy of the Combination of Zimberelimab, Domvanalimab and Sacituzumab Govitecan as 1L Therapy for PD-L1 Positive Advanced TNBC

NCT ID: NCT07134556

This clinical trial is testing a new combination of three medicines—zimberelimab, domvanalimab, and sacituzumab govitecan—as the first treatment for people with advanced or metastatic triple-negati...

Not yet recruiting

Phase: PHASE2 Type: interventional

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

NCT ID: NCT06999187

This clinical trial is looking at a new treatment called DR-0202 for patients with certain types of advanced cancers, including triple-negative breast cancer and non-small cell lung cancer, among o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Fairfax, Virginia, United States, Denver, Colorado, United States +8 more

Sacituzumab Tirumotecan Plus Anlotinib for Metastatic Triple Negative Breast Cancer

NCT ID: NCT07139470

This clinical trial is studying a new combination treatment for people with metastatic triple-negative breast cancer (TNBC), a type of breast cancer that does not have certain hormone receptors and...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Tianjin, Tianjin, China

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

NCT ID: NCT05579366

This clinical trial is investigating a new drug called PRO1184 for patients with various types of advanced solid tumors, including different forms of ovarian, lung, and breast cancer. The main goal...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Seattle, Washington, United States +43 more

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

NCT ID: NCT06465069

This clinical trial is studying a new drug called LY4052031 to see if it is safe and effective for patients with advanced or metastatic solid tumors, including types of bladder, breast, lung, and p...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, New York, New York, United States +36 more

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

NCT ID: NCT04434040

The ASPRIA clinical trial is looking into whether a combination of two drugs, sacituzumab govitecan and atezolizumab, can help prevent breast cancer from coming back in patients who still have some...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +8 more

A Dose Randomization Study of Bulumtatug Fuvedotin in TNBC Patients Previously Treated With ADCs

NCT ID: NCT06908928

This clinical trial is investigating a new treatment called bulumtatug fuvedotin for patients with triple-negative breast cancer (TNBC) who have already received certain types of therapies. The pur...

Recruiting

Phase: PHASE1 Type: interventional Locations: New York, New York, United States, Nashville, Tennessee, United States +3 more

Anthracycline-Free Neoadjuvant Chemoimmunotherapy for Triple Negative Breast Cancer Patients

NCT ID: NCT06845319

This clinical trial is investigating a new treatment approach for patients with triple-negative breast cancer (TNBC) who cannot receive standard chemotherapy due to heart-related health issues. The...

Not yet recruiting

Phase: PHASE2 Type: interventional

Study of Screening Brain MRIs in Stage IV Breast Cancer

NCT ID: NCT05115474

This clinical trial is studying the use of brain MRI scans to check for any potential issues in patients with advanced breast cancer who do not have any neurological symptoms. Specifically, it look...

Recruiting

Type: observational Locations: Tampa, Florida, United States, Clearwater, Florida, United States

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

NCT ID: NCT05633654

The ASCENT-05 clinical trial is studying a new treatment approach for patients with triple negative breast cancer (TNBC) who still have cancer remaining after surgery and previous therapy. This tri...

Recruiting

Phase: PHASE3 Type: interventional Locations: Worcester, Massachusetts, United States, Sacramento, California, United States +233 more

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NCT ID: NCT06586957

This clinical trial is studying a new treatment called NKT3964 for adults with advanced or metastatic solid tumors, which are cancers that have spread beyond their original location. The trial aims...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Nashville, Tennessee, United States +6 more

NeoAdj. Therapy Comparing Sacituzumab Govitecan (SG) vs. SG+Pembrolizumab in Low-risk, Triple-neg. EBC (ADAPT-TN-III)

NCT ID: NCT06081244

The clinical trial titled ADAPT-TN-III is investigating a new treatment approach for women with low-risk, triple-negative breast cancer (TNBC). Specifically, it’s comparing two groups: one receivin...

Recruiting

Phase: PHASE3 Type: interventional Locations: Ulm, , Germany, Tübingen, , Germany +47 more

A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer

NCT ID: NCT06926920

This clinical trial is exploring a new way to give a drug called sacituzumab govitecan to patients with advanced triple-negative breast cancer, a type that can be particularly hard to treat. The re...

Recruiting

Phase: PHASE1 Type: interventional Locations: Nashville, Tennessee, United States, Seoul, , Korea, Republic Of +8 more

ProAgio in Combination With Gemcitabine in Patients With Metastatic Triple Negative Breast Cancer

NCT ID: NCT06460298

This clinical trial is studying a new treatment called ProAgio in combination with a standard chemotherapy drug called Gemcitabine for patients with metastatic triple negative breast cancer. Triple...

Recruiting

Phase: PHASE1 Type: interventional Locations: Atlanta, Georgia, United States, Atlanta, Georgia, United States

A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors

NCT ID: NCT06700070

This clinical trial is exploring the effects of a new treatment called PBA-0111, which is given directly into tumors using a special device. The goal is to understand how this treatment works withi...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Shreveport, Louisiana, United States

BCD-236 in Combination With Chemotherapy in Patients With Relapsed and/or Metastatic Triple Negative Breast Cancer

NCT ID: NCT07108309

This clinical trial is testing a new treatment called BCD-236 combined with chemotherapy for women with a type of breast cancer known as triple negative breast cancer (TNBC) that has come back or s...

Recruiting

Phase: PHASE2 Type: interventional Locations: Barnaul, , Russian Federation, Saint Petersburg, , Russian Federation +45 more

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

NCT ID: NCT07115043

This clinical trial is testing the safety of a new medicine called AZD6750 in adults who have certain advanced or spreading types of solid tumors, such as melanoma (a type of skin cancer), lung can...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, San Antonio, Texas, United States +4 more

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

NCT ID: NCT04468061

This clinical trial is studying a new treatment approach for patients with metastatic triple-negative breast cancer (TNBC) that does not express a protein called PD-L1. The trial is testing two inv...

Recruiting

Phase: PHASE2 Type: interventional Locations: Charleston, South Carolina, United States, Boston, Massachusetts, United States +11 more

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT ID: NCT04585750

The PYNNACLE clinical trial is studying a new treatment called PC14586, aimed at patients with advanced solid tumors that have a specific genetic mutation known as TP53 Y220C. This trial is current...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Charleston, South Carolina, United States +95 more

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