Clinical Trials for Triple Negative Breast Neoplasms

Find clinical trials for triple negative breast neoplasms. Discover research opportunities and treatment options in your area.

21 Active Trials Found

Showing 21 trials on this page

Page 1 of 2

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

NCT ID: NCT06841354

This clinical trial is studying the effectiveness of a drug called sacituzumab tirumotecan (also known as Sac-TMT) both on its own and in combination with another drug called pembrolizumab for trea...

Recruiting

Phase: PHASE3 Type: interventional Locations: Reno, Nevada, United States, Petah Tikva, Rinat, Israel +56 more

A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors

NCT ID: NCT06157892

This clinical trial is looking at a new treatment option for people with advanced solid tumors, specifically breast and gastric cancers that have a certain protein called HER2. HER2 can make these ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Tampa, Florida, United States, Saint Louis, Missouri, United States +155 more

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

NCT ID: NCT06966700

This clinical trial is studying a new treatment called sacituzumab tirumotecan (or sac-TMT) for people with certain types of breast cancer, specifically high-risk, early-stage triple-negative breas...

Recruiting

Phase: PHASE3 Type: interventional Locations: Hialeah, Florida, United States, Baltimore, Maryland, United States +4 more

A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

NCT ID: NCT05544929

This clinical trial is exploring the safety and effectiveness of a new treatment called KFA115, both on its own and in combination with another medication called pembrolizumab, for patients with ce...

Recruiting

Phase: PHASE1 Type: interventional Locations: Toronto, Ontario, Canada, Pittsburgh, Pennsylvania, United States +24 more

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

NCT ID: NCT05208762

This clinical trial is studying a new drug called PF-08046054/SGN-PDL1V to see how safe it is for patients with advanced solid tumors, which are cancers that have spread in the body or cannot be su...

Recruiting

Phase: PHASE1 Type: interventional Locations: Iowa City, Iowa, United States, Milano, , Italy +73 more

Bicalutamide and Abemaciclib in Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer

NCT ID: NCT06365788

This clinical trial is studying the effects of two medications, bicalutamide and abemaciclib, in women with a specific type of breast cancer called androgen receptor-positive triple-negative breast...

Recruiting

Phase: PHASE2 Type: interventional Locations: Leuven, , Belgium, Antwerp, , Belgium +4 more

A Study of Sacituzumab Govitecan Plus Toripalimab Versus Toripalimab Plus Nab-Paclitaxel in PD-L1 Positive Advanced TNBC

NCT ID: NCT07040644

This clinical trial is studying a new combination of medicines to treat a specific type of advanced breast cancer called triple-negative breast cancer (TNBC) that tests positive for a protein calle...

Not yet recruiting

Phase: PHASE2 Type: interventional Locations: Guangzhou, Guangdong, China

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

NCT ID: NCT06246968

This clinical trial is looking at the use of a medication called pembrolizumab, combined with a treatment called cryoablation, for people with advanced types of breast cancer, especially those with...

Recruiting

Phase: PHASE1 Type: interventional Locations: Middletown, New Jersey, United States, Montvale, New Jersey, United States +5 more

A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

NCT ID: NCT06400472

This clinical trial is studying a new drug called LY4170156 to see if it is safe and effective for people with advanced solid tumors, such as certain types of ovarian, endometrial, cervical, lung, ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Lyon, , France, New York, New York, United States +15 more

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NCT ID: NCT06586957

This clinical trial is studying a new treatment called NKT3964 for adults with advanced or metastatic solid tumors, which are cancers that have spread beyond their original location. The trial aims...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Nashville, Tennessee, United States +6 more

Capecitabine Plus Pembrolizumab in Patients With Triple Negative Breast Cancer After Chemo-immunotherapy and Surgery

NCT ID: NCT05973864

This clinical trial is studying the effectiveness and safety of two drugs, pembrolizumab and capecitabine, for patients with triple-negative breast cancer (TNBC) who still have cancer present after...

Recruiting

Phase: PHASE2 Type: interventional Locations: Paris, , France, Bayonne, , France +6 more

Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer

NCT ID: NCT05485766

This clinical trial is studying a new treatment approach for patients with triple negative breast cancer (TNBC) who have specific gene mutations known as BRCA1 or BRCA2. The researchers want to see...

Recruiting

Phase: PHASE2 Type: interventional Locations: Gifu, , Japan, Tokyo, , Japan +2 more

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

NCT ID: NCT05020860

This clinical trial is studying how well a patient's clinical response to chemotherapy before surgery can predict how much of the breast cancer remains after surgery. In simpler terms, the research...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States, Houston, Texas, United States +1 more

A Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors

NCT ID: NCT04895709

This clinical trial is studying a new treatment called BMS-986340 for patients with advanced solid tumors, which include various types of cancers like cervical cancer, lung cancer, and breast cance...

Recruiting

Phase: PHASE1 Type: interventional Locations: Iowa City, Iowa, United States, Edmonton, , Canada +105 more

Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies

NCT ID: NCT04561362

This clinical trial is studying a new treatment called BT8009 for patients with advanced solid tumors, particularly those that express a protein called Nectin-4. The trial is open to adults aged 65...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bordeaux, , France, Lyon, , France +33 more

NordicTrip, a Translational Study of Preoperative Chemotherapy in TNBC

NCT ID: NCT04335669

The NordicTrip clinical trial is studying a new approach to treat early-stage triple-negative breast cancer (TNBC) before surgery. Researchers want to find out if adding a drug called capecitabine ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Copenhagen, , Denmark, Sundsvall, , Sweden +26 more

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer

NCT ID: NCT06380816

This clinical trial is testing a new drug called UCB4594 in people with advanced cancer. UCB4594 is a monoclonal antibody, which means it's designed to attach to a specific protein found in high am...

Recruiting

Phase: PHASE1 Type: interventional Locations: Manchester, , United Kingdom, Southampton, , United Kingdom

Utidelone (UTD1) Plus Capecitabine in Non-pCR TNBC After Neoadjuvant Therapy

NCT ID: NCT06385990

This clinical trial is studying a new treatment approach for women with triple-negative breast cancer (TNBC) who did not achieve complete recovery after initial chemotherapy. The trial is testing a...

Recruiting

Phase: PHASE2 Type: interventional Locations: Changsha, Hunan, China

Image-based AI Predictive Biomarkers for Precision Neoadjuvant Triple-negative Breast Cancer Treatment

NCT ID: NCT05435352

This clinical trial is studying a new tool developed by Pear Bio that uses an organ-on-a-chip device to test how well a patient's tumor responds to different chemotherapy treatments. The goal is to...

Recruiting

Type: observational Locations: London, , United Kingdom, London, , United Kingdom +1 more

Comparative Efficacy of Xiaopi Granules and Decoction in Triple-negative Breast Cancer: a Randomized Controlled Trial

NCT ID: NCT06154109

This clinical trial is studying the effectiveness of two different forms of a treatment called Xiaopi in women with triple-negative breast cancer, which is a type of breast cancer that does not res...

Not yet recruiting

Phase: PHASE2 Type: interventional

Related Conditions

Breast Cancer View clinical trials → Stroke View clinical trials → Obesity View clinical trials → Cancer View clinical trials → Healthy View clinical trials → Prostate Cancer View clinical trials →

Search All Trials Browse All Conditions