Clinical Trials for Unresectable Gastroesophageal Junction Adenocarcinoma

Find clinical trials for unresectable gastroesophageal junction adenocarcinoma. Discover research opportunities and treatment options in your area.

8 Active Trials Found

Showing 8 trials on this page

Page 1 of 1

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

NCT ID: NCT06203600

The PARAMUNE Trial is studying how well a new treatment combining nivolumab with standard therapies works for people with advanced stomach or esophageal cancer. Nivolumab is a type of immunotherapy...

Recruiting

Phase: PHASE2 Type: interventional Locations: Chicago, Illinois, United States, New Haven, Connecticut, United States +378 more

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

NCT ID: NCT04704661

The DASH Trial is a clinical study exploring the safety and effectiveness of two anti-cancer drugs, DS-8201a and AZD6738, for patients with various types of advanced solid tumors that express the H...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bethesda, Maryland, United States, Saint Louis, Missouri, United States +22 more

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

NCT ID: NCT06364410

This clinical trial is investigating the safety and effectiveness of two anticancer drugs, trastuzumab deruxtecan and azenosertib, for patients with certain types of stomach or gastroesophageal jun...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Houston, Texas, United States

Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma

NCT ID: NCT05041153

This clinical trial is studying the use of two medications, pembrolizumab and lenvatinib, to treat patients with advanced stomach cancer that either cannot be removed by surgery or has spread to ot...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Houston, Texas, United States

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

NCT ID: NCT06251973

This clinical trial is studying a new treatment approach for people with advanced cancers of the esophagus, stomach, or the area where the esophagus meets the stomach. The treatment combines four d...

Recruiting

Phase: PHASE2 Type: interventional Locations: New York, New York, United States, Basking Ridge, New Jersey, United States +5 more

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

NCT ID: NCT05677490

This clinical trial is comparing two different chemotherapy treatments for patients with advanced or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric cancer. The trial is...

Recruiting

Phase: PHASE3 Type: interventional Locations: Charleston, South Carolina, United States, Washington, District Of Columbia, United States +827 more

Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma

NCT ID: NCT05651594

This clinical trial is studying the potential benefits of adding a medication called propranolol to a combination treatment of pembrolizumab and standard chemotherapy for patients with esophageal o...

Recruiting

Phase: PHASE2 Type: interventional Locations: Buffalo, New York, United States

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT ID: NCT05269381

This clinical trial is investigating a new type of personalized vaccine designed to help the immune system recognize and attack advanced solid tumors, which are cancers that have spread beyond thei...

Recruiting

Phase: PHASE1 Type: interventional Locations: Jacksonville, Florida, United States

Related Conditions

Breast Cancer View clinical trials → Stroke View clinical trials → Obesity View clinical trials → Cancer View clinical trials → Prostate Cancer View clinical trials → Healthy View clinical trials →

Search All Trials Browse All Conditions