Clinical Trials for Unresectable Solid Tumor

Find clinical trials for unresectable solid tumor. Discover research opportunities and treatment options in your area.

11 Active Trials Found

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A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

NCT ID: NCT06244771

This clinical trial is studying a new treatment called FMC-376 for patients with advanced solid tumors that have a specific genetic change known as the KRAS G12C mutation. These tumors can include ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Boston, Massachusetts, United States +17 more

Palliative Spatially Fractionated (GRID) Radiotherapy Using Intensity Modulated Proton Therapy

NCT ID: NCT05831579

This clinical trial is investigating a new approach to radiation therapy called Spatially Fractionated Radiotherapy (SFRT or GRID) using a technique called proton therapy. It aims to treat patients...

Recruiting

Phase: NA Type: interventional Locations: Saint Louis, Missouri, United States

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

NCT ID: NCT06778863

This clinical trial is studying a new treatment called CLSP-1025 for adults with certain types of solid tumors that have a specific genetic mutation known as p53 R175H. These tumors can include adv...

Recruiting

Phase: PHASE1 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Hackensack, New Jersey, United States +12 more

A Beta-only IL-2 ImmunoTherapY Study

NCT ID: NCT05086692

This clinical trial, called the Beta-only IL-2 ImmunoTherapY Study, is looking to test a new treatment called MDNA11 for patients with advanced solid tumors, which are types of cancer that have spr...

Recruiting

Phase: PHASE1 Type: interventional Locations: San Diego, California, United States, Baltimore, Maryland, United States +31 more

CSB-321 Ph 1 in Immunotherapy for the Treatment of Cancer

NCT ID: NCT07057349

This clinical trial is studying a new way to help doctors see how a special type of cancer treatment, called immunotherapy, is working in people with advanced cancers that have spread or cannot be ...

Not yet recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States

A Multicenter Study of Avapritinib Efficacy and Safety of Metastatic or Unresectable Gastrointestinal Stromal Tumors

NCT ID: NCT05464875

This clinical trial is studying a medication called Avapritinib for patients with metastatic or unresectable gastrointestinal stromal tumors (GISTs), which are a type of cancer that affects the dig...

Recruiting

Type: observational Locations: Guangzhou, Guangdong, China

Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA

NCT ID: NCT05461664

This clinical trial is studying a medication called Avapritinib to see how well it works for patients with a type of cancer known as gastrointestinal stromal tumors (GIST) that cannot be surgically...

Recruiting

Type: observational Locations: Guangzhou, Guangdong, China

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, As a Single Agent in Advanced Solid Tumor Patients and in Combination with Fulvestrant in Patients with Advanced Breast Cancer

NCT ID: NCT05216432

This clinical trial is testing a new drug called RLY-2608, which is designed to target a specific genetic mutation (PIK3CA) found in some solid tumors, including certain types of breast cancer. The...

Recruiting

Phase: PHASE1 Type: interventional Locations: Ann Arbor, Michigan, United States, Boston, Massachusetts, United States +36 more

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

NCT ID: NCT06302621

This clinical trial is examining the safety and effectiveness of two drugs, Afatinib and Pemigatinib, when used together to treat patients with advanced solid tumors that cannot be surgically remov...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States

COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases

NCT ID: NCT06185556

The COLDFIRE-III Trial is a clinical study that aims to compare two treatment methods for patients with colorectal cancer that has spread to the liver and cannot be surgically removed. The treatmen...

Recruiting

Phase: PHASE2 Type: interventional Locations: Amsterdam, Noord Holland, Netherlands

A Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancer

NCT ID: NCT06184035

This clinical trial is investigating a new treatment called [177Lu]Lu-SN201 for adults with advanced solid tumors, which are cancers that have spread and cannot be surgically removed. The main goal...

Recruiting

Phase: PHASE1 Type: interventional Locations: Adelaide, South Australia, Australia, Melbourne, Victoria, Australia

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