A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

NCT ID: NCT06999187

This clinical trial is looking at a new treatment called DR-0202 for patients with certain types of advanced cancers, including triple-negative breast cancer and non-small cell lung cancer, among o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Fairfax, Virginia, United States, Denver, Colorado, United States +8 more

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

NCT ID: NCT06943521

This clinical trial is studying a new medication called MT-4561 to see how safe and effective it is for patients with various advanced solid tumors, such as head and neck cancer, lung cancer, breas...

Recruiting

Phase: PHASE1 Type: interventional Locations: Los Angeles, California, United States, Houston, Texas, United States +1 more

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

NCT ID: NCT05581004

This clinical trial is testing a new treatment called RO7502175, both on its own and in combination with another medication called atezolizumab. The study is designed for adults who have locally ad...

Recruiting

Phase: PHASE1 Type: interventional Locations: Detroit, Michigan, United States, Atlanta, Georgia, United States +44 more

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

NCT ID: NCT06774131

This clinical trial is studying a new treatment called UGN-104 for people with low-grade upper tract urothelial cancer (LG-UTUC), which is a type of cancer found in the upper urinary tract. The goa...

Recruiting

Phase: PHASE3 Type: interventional Locations: Hershey, Pennsylvania, United States, Aventura, Florida, United States +1 more

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

NCT ID: NCT04879329

This clinical trial is testing a new treatment for patients with urothelial cancer that shows a specific marker called HER2. The study is looking at whether a drug called disitamab vedotin, either ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Orange, California, United States, Columbus, Ohio, United States +263 more

A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

NCT ID: NCT04260802

This clinical trial is investigating a new treatment called OC-001 for patients with advanced or spreading cancers, including types like triple-negative breast cancer, gastric cancer, and non-small...

Recruiting

Phase: PHASE1 Type: interventional Locations: Edmonton, Alberta, Canada, Toronto, Ontario, Canada +3 more

Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

NCT ID: NCT07043972

This clinical trial is studying whether a chemotherapy treatment called gemcitabine and carboplatin (GC) can help people with advanced bladder or urinary tract cancer (urothelial carcinoma) who hav...

Recruiting

Phase: PHASE2 Type: interventional Locations: Philadelphia, Pennsylvania, United States, Philadelphia, Pennsylvania, United States

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

NCT ID: NCT06695845

This clinical trial is studying a new treatment called zanidatamab for patients with certain types of solid tumors that have high levels of a protein called HER2. These tumors include breast, gastr...

Recruiting

Phase: PHASE2 Type: interventional Locations: Detroit, Michigan, United States, Houston, Texas, United States +20 more

Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

NCT ID: NCT05911295

This clinical trial is studying two different treatment options for patients with urothelial cancer, which can affect the bladder, kidneys, or urinary tubes. The researchers want to find out if a c...

Recruiting

Phase: PHASE3 Type: interventional Locations: New York, New York, United States, Knoxville, Tennessee, United States +454 more

PRO1107 in Patients With Advanced Solid Tumors

NCT ID: NCT06171789

This clinical trial is studying a new treatment called PRO1107 for patients with advanced solid tumors, including types of cancer like endometrial, ovarian, triple negative breast, gastroesophageal...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Sarasota, Florida, United States +4 more

Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

NCT ID: NCT06262516

This clinical trial is studying the effects of a surgical procedure called nephroureterectomy, which involves removing the kidney and part of the ureter, in patients with a type of cancer called up...

Recruiting

Phase: NA Type: interventional Locations: Cleveland, Ohio, United States, Cleveland, Ohio, United States

Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?

NCT ID: NCT07037589

This clinical trial is looking at women aged 50 and older who have sudden blood in their urine caused by a bladder infection, a condition called acute hemorrhagic cystitis. The study wants to find ...

Not yet recruiting

Type: observational

Study to Evaluate Adverse Events and Change in Disease Activity When Intravenously (IV) Infused Livmoniplimab is Used in Combination With IV Infused Budigalimab in Adult Participants With Urothelial Carcinoma (UC)

NCT ID: NCT06632951

This clinical trial is studying a new treatment combination for adults with urothelial carcinoma (UC), a type of cancer that affects the bladder and other parts of the urinary system. Researchers w...

Recruiting

Phase: PHASE2 Type: interventional Locations: Springdale, Arkansas, United States, Haifa, , Israel +36 more

Management of Cisplatin-Ineligible Patients With Metastatic Bladder Cancer and The Role of Geriatric Assessments

NCT ID: NCT06138561

This clinical trial is focused on finding the best ways to treat older patients with advanced bladder cancer who cannot tolerate certain chemotherapy drugs, specifically cisplatin. Researchers want...

Recruiting

Type: observational Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States

Memory-like Natural Killer (NK) Cell Therapy in Patients With Renal Cell Carcinoma or Urothelial Carcinoma

NCT ID: NCT06318871

This clinical trial is exploring a new type of treatment for patients with advanced kidney cancer (renal cell carcinoma) and bladder cancer (urothelial carcinoma). The focus is on using a special k...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +1 more

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

NCT ID: NCT05078047

This clinical trial is investigating whether a less frequent administration of immunotherapy (IO) can be just as effective as the standard treatment schedule for patients with certain types of adva...

Recruiting

Phase: PHASE3 Type: interventional Locations: Nice, , France, Rennes, , France +38 more

Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Cisplatin-eligible Upper Tract Urothelial Cancer

NCT ID: NCT06356155

This clinical trial is exploring the combination of two medications, enfortumab vedotin and pembrolizumab, for patients with a specific type of cancer called upper tract urothelial carcinoma. This ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Ann Arbor, Michigan, United States

A Phase 2 Study to Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma

NCT ID: NCT05335941

This clinical trial is looking at a new combination treatment for patients with advanced or metastatic urothelial carcinoma (a type of bladder cancer) who have a specific genetic deficiency known a...

Recruiting

Phase: PHASE2 Type: interventional Locations: Houston, Texas, United States

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

NCT ID: NCT06293898

This clinical trial is studying a new treatment called BL-M07D1 for patients with certain types of advanced cancers that have a protein called HER2. The goal is to find out if this treatment is saf...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Nashville, Tennessee, United States +12 more

Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma

NCT ID: NCT03967977

This clinical trial is studying a new treatment for urothelial carcinoma, which is a type of cancer that affects the bladder and urinary system. The researchers want to find out if combining a medi...

Recruiting

Phase: PHASE3 Type: interventional Locations: Tainan, , Taiwan, Beijing, Beijing, China +91 more

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Clinical Trials for Urothelial Carcinoma

99 Active Trials Found

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

PRO1107 in Patients With Advanced Solid Tumors

Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?

Study to Evaluate Adverse Events and Change in Disease Activity When Intravenously (IV) Infused Livmoniplimab is Used in Combination With IV Infused Budigalimab in Adult Participants With Urothelial Carcinoma (UC)

Management of Cisplatin-Ineligible Patients With Metastatic Bladder Cancer and The Role of Geriatric Assessments

Memory-like Natural Killer (NK) Cell Therapy in Patients With Renal Cell Carcinoma or Urothelial Carcinoma

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Cisplatin-eligible Upper Tract Urothelial Cancer

A Phase 2 Study to Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma

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