Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)

NCT ID: NCT05653349

This clinical trial is studying a medication called ianalumab to see how well it works in helping adults with a condition called primary immune thrombocytopenia (ITP) maintain a healthy platelet co...

Recruiting

Phase: PHASE3 Conditions: Primary Immune Thrombocytopenia (ITP)

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

NCT ID: NCT05939414

This clinical trial is studying a new treatment called lutetium (177Lu) vipivotide tetraxetan for men with oligometastatic prostate cancer (OMPC), which means their cancer has spread to a few place...

Recruiting

Phase: PHASE3 Conditions: Oligometastatic Prostate Cancer (OMPC)

CAR-T Long Term Follow Up (LTFU) Study

NCT ID: NCT02445222

The CAR-T Long Term Follow Up Study is designed to check on the long-term safety and effectiveness of patients who have received CAR-T therapy, a type of treatment that uses genetically modified ce...

Recruiting

Phase: PHASE3 Conditions: Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

NCT ID: NCT05156281

This clinical trial is studying the effectiveness and safety of a new treatment called remibrutinib compared to an existing drug, teriflunomide, in people with relapsing multiple sclerosis (RMS). R...

Recruiting

Phase: PHASE3 Conditions: Relapsing Multiple Sclerosis

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

NCT ID: NCT06393374

This clinical trial is studying a new treatment for patients with triple-negative breast cancer (TNBC) who did not completely respond to earlier treatment before surgery. The researchers want to fi...

Recruiting

Phase: PHASE3 Conditions: Triple-Negative Breast Cancer

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

NCT ID: NCT06717347

This clinical trial is studying a new treatment for patients with diffuse large B-cell lymphoma (DLBCL), a type of cancer that affects the lymphatic system. Researchers want to see if adding a drug...

Recruiting

Phase: PHASE3 Conditions: Diffuse Large B-Cell Lymphoma

Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

NCT ID: NCT05609578

This clinical trial, called CA239-0010, is exploring a new treatment approach for patients with advanced non-small cell lung cancer (NSCLC) who have a specific genetic mutation known as KRAS G12C. ...

Recruiting

Phase: PHASE2 Conditions: Metastatic Lung Cancer, Advanced NSCLC

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

NCT ID: NCT06141473

This clinical trial is studying the effectiveness and safety of a medication called frexalimab (also known as SAR441344) for adults who have relapsing forms of multiple sclerosis (MS). The goal is ...

Recruiting

Phase: PHASE3 Conditions: Multiple Sclerosis

FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS)

NCT ID: NCT06111586

The FABULINUS trial is studying a new treatment called frexalimab for people with Type 1 Diabetes Mellitus (T1D) who are already using insulin. The goal of the trial is to see if frexalimab can hel...

Recruiting

Phase: PHASE2 Conditions: Type 1 Diabetes Mellitus

Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

NCT ID: NCT03955445

This clinical trial is studying a medication called iptacopan to see how well it works over a long period for patients with conditions known as C3 glomerulopathy or idiopathic immune-complex-membra...

Recruiting

Phase: PHASE3 Conditions: C3 Glomerulopathy, Immune-complex-membranoproliferative Glomerulonephritis

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

NCT ID: NCT05268289

This clinical trial is studying a new medication called iptacopan (also known as LNP023) for patients with active lupus nephritis, a condition where the immune system attacks the kidneys. The trial...

Recruiting

Phase: PHASE2 Conditions: Lupus Nephritis

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

NCT ID: NCT06492616

This clinical trial is studying a new medication called elacestrant to see how well it works compared to standard hormonal treatments in women and men with early-stage breast cancer that is hormone...

Recruiting

Phase: PHASE3 Conditions: Breast Cancer

Asciminib Roll-over Study

NCT ID: NCT04877522

The Asciminib Roll-over Study is a clinical trial designed to assess the long-term safety of a medication called asciminib for patients with chronic myelogenous leukemia (CML) who have previously p...

Recruiting

Phase: PHASE4 Conditions: Chronic Myelogenous Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004)

NCT ID: NCT06726265

The TACTI-004 clinical trial is studying a new treatment approach for adults with advanced or metastatic non-small cell lung cancer (NSCLC), which is a type of lung cancer that has spread beyond th...

Recruiting

Phase: PHASE3 Conditions: Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult Patients With Moderate to Severe Hidradenitis Suppurativa

NCT ID: NCT06840392

This clinical trial is investigating the effectiveness and safety of a medication called remibrutinib for adults with moderate to severe hidradenitis suppurativa (HS), a skin condition that causes ...

Recruiting

Phase: PHASE3 Conditions: Hidradenitis Suppurativa

Evaluation of Adherence With Bisphosphonates and Calcium and Vitamin D Supplements in Women With Postmenopausal Osteoporosis

NCT ID: NCT07105163

This clinical trial is looking at how well women with postmenopausal osteoporosis stick to their treatment plans, which usually include taking medicines called bisphosphonates along with calcium an...

Recruiting

Conditions: Post Menopausal Osteoporosis

Secukinumab Open Label Roll-over Extension Protocol

NCT ID: NCT04638647

The Secukinumab Open Label Roll-over Extension Protocol is a clinical trial that aims to understand the long-term safety of a medication called secukinumab for people with autoimmune and inflammato...

Recruiting

Phase: PHASE4 Conditions: Autoimmunity, Inflammation

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)

NCT ID: NCT06331312

This clinical trial is looking at the long-term safety and tolerability of a medication called secukinumab for patients with polymyalgia rheumatica (PMR), a condition that causes muscle pain and st...

Recruiting

Phase: PHASE3 Conditions: Polymyalgia Rheumatica

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

NCT ID: NCT06597019

This clinical trial is studying a medication called inclisiran to see how safe and effective it is for children aged 6 to under 12 years who have a condition known as heterozygous familial hypercho...

Recruiting

Phase: PHASE3 Conditions: Familial Hypercholesterolemia - Heterozygous

Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study

NCT ID: NCT06958315

The INSPIRE Study is a clinical trial looking at a medication called inclisiran (Leqvio®) for patients with certain heart and blood vessel conditions, specifically atherosclerotic vascular disease ...

Recruiting

Conditions: Heterozygous Familial Hypercholesterolemia, Atherosclerotic Vascular Disease

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Clinical Trials in Sevilla, Andalucia

36 Active Trials Found in Sevilla

Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

CAR-T Long Term Follow Up (LTFU) Study

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS)

Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Asciminib Roll-over Study

Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004)

Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult Patients With Moderate to Severe Hidradenitis Suppurativa

Evaluation of Adherence With Bisphosphonates and Calcium and Vitamin D Supplements in Women With Postmenopausal Osteoporosis

Secukinumab Open Label Roll-over Extension Protocol

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study