LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

NCT ID: NCT06632444

The LIVERAGE™ clinical trial is studying a medication called survodutide to see if it can help adults with a liver disease known as Metabolic Dysfunction Associated Steatohepatitis (MASH) who also ...

Recruiting

Phase: PHASE3 Conditions: Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis (MASH)

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

NCT ID: NCT07011745

This clinical trial, called ADAGIO-2, is investigating a new treatment called KarXT + KarX-EC for adults with Alzheimer's disease who experience agitation. Agitation can include feelings of restles...

Recruiting

Phase: PHASE3 Conditions: Alzheimer Disease

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

NCT ID: NCT06937229

The ADAGIO-3 study is a clinical trial focused on testing a new treatment for agitation in people with Alzheimer’s Disease. This trial will specifically look at the long-term effects and safety of ...

Not yet recruiting

Phase: PHASE3 Conditions: Alzheimer Disease, Agitation

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

NCT ID: NCT07043400

This clinical trial is studying a cancer treatment called tislelizumab for adults with advanced stomach cancer or cancer where the stomach meets the esophagus. The goal is to compare two ways of gi...

Not yet recruiting

Phase: PHASE3 Conditions: Gastroesophageal Junction Adenocarcinoma, Metastatic Gastric Adenocarcinoma

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

NCT ID: NCT07064473

This clinical trial is studying whether a new medicine called vicadrostat, when taken together with an existing diabetes medicine called empagliflozin, can help lower the risk of heart problems in ...

Recruiting

Phase: PHASE3 Conditions: Hypertension, Diabetes Mellitus, Type 2 +1 more

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

ACP-204 in Adults With Alzheimer's Disease Psychosis

NCT ID: NCT06159673

This clinical trial is studying a new medication called ACP-204 for adults with Alzheimer's Disease Psychosis (ADP), which involves experiencing confusion or delusions related to Alzheimer's diseas...

Recruiting

Phase: PHASE2 Conditions: Alzheimer's Disease Psychosis

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NCT ID: NCT06215716

This clinical trial is studying a medication called efruxifermin (EFX) to see if it can help people with non-cirrhotic Nonalcoholic Steatohepatitis (NASH) or Metabolic Dysfunction-Associated Steato...

Recruiting

Phase: PHASE3 Conditions: NASH With Fibrosis, MASH With Fibrosis

A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

NCT ID: NCT06880744

This clinical trial is looking at how well a medication called risankizumab works compared to another medication called vedolizumab in treating adults with moderate to severe ulcerative colitis (UC...

Recruiting

Phase: PHASE3 Conditions: Ulcerative Colitis

A Study to Test How BI 1584862 is Taken up in the Blood of People With and Without Liver Problems

NCT ID: NCT06957756

This clinical trial is designed to study how a medication called BI 1584862 is processed in the blood of adults who have liver problems, as well as those who do not have any liver issues. The resea...

Recruiting

Phase: PHASE1 Conditions: Hepatic Insufficiency

A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

NCT ID: NCT04929210

This clinical trial is studying a medication called guselkumab to see how well it works for people with active psoriatic arthritis (PsA) that affects the spine and pelvis. The goal is to find out i...

Recruiting

Phase: PHASE4 Conditions: Arthritis, Psoriatic

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

NCT ID: NCT06237452

The VE303 clinical trial is studying a new treatment called VE303 to see if it can help prevent repeated infections caused by Clostridioides difficile, often called C. diff. This trial is open to t...

Recruiting

Phase: PHASE3 Conditions: Clostridium Difficile, Clostridioides Difficile Infection +8 more

A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

NCT ID: NCT06752668

This clinical trial is studying a new medication called ORX750 to see how safe it is and how well it works for people with narcolepsy (both types 1 and 2) and idiopathic hypersomnia, a condition th...

Recruiting

Phase: PHASE2 Conditions: Idiopathic Hypersomnia, Narcolepsy Type 1 +1 more

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation

NCT ID: NCT05090371

This clinical trial is studying whether patients with relapsing-remitting multiple sclerosis (MS) who have not experienced a relapse in the past year would benefit from switching to a medication ca...

Recruiting

Phase: PHASE4 Conditions: Relapsing-Remitting Multiple Sclerosis

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

NCT ID: NCT05615844

The Beads vs Vac trial is a clinical study looking at two different ways to manage severe open tibia fractures, which are serious injuries to the shinbone that may require multiple surgeries to cle...

Recruiting

Phase: PHASE3 Conditions: Open tíbia Fracture

A Study to Investigate the Efficacy of Durvalumab Plus Tremelimumab in Combination With Chemotherapy Compared With Pembrolizumab in Combination With Chemotherapy in Metastatic NSCLC Patients With Non-squamous Histology Who Have Mutations and/or Co-mutations in STK11, KEAP1, or KRAS

NCT ID: NCT06008093

This clinical trial is exploring new treatment options for patients with advanced non-small cell lung cancer (NSCLC) that cannot be surgically removed. Specifically, it compares two different combi...

Recruiting

Phase: PHASE3 Conditions: Carcinoma, Non-Small-Cell Lung

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT ID: NCT06312176

This clinical trial is studying a new treatment option for patients with a specific type of breast cancer called hormone receptor positive and HER2 negative (HR+/HER2-). The researchers want to see...

Recruiting

Phase: PHASE3 Conditions: Breast Neoplasms

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

NCT ID: NCT06393374

This clinical trial is studying a new treatment for patients with triple-negative breast cancer (TNBC) who did not completely respond to earlier treatment before surgery. The researchers want to fi...

Recruiting

Phase: PHASE3 Conditions: Triple-Negative Breast Cancer

A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)

NCT ID: NCT06465186

This clinical trial is studying a new medicine called efinopegdutide to see if it can help people with a liver disease known as metabolic dysfunction-associated steatohepatitis (MASH), which is cau...

Recruiting

Phase: PHASE2 Conditions: NAFLD, Non-alcoholic Fatty Liver Disease +3 more

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

NCT ID: NCT06559306

This clinical trial is studying a medication called seltorexant to see how well it helps adults and elderly people who have major depressive disorder (MDD) along with insomnia symptoms. The goal is...

Recruiting

Phase: PHASE3 Conditions: Depressive Disorder, Major

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Clinical Trials in Chandler, Arizona

126 Active Trials Found in Chandler

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

ACP-204 in Adults With Alzheimer's Disease Psychosis

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

A Study to Test How BI 1584862 is Taken up in the Blood of People With and Without Liver Problems

A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

A Study to Investigate the Efficacy of Durvalumab Plus Tremelimumab in Combination With Chemotherapy Compared With Pembrolizumab in Combination With Chemotherapy in Metastatic NSCLC Patients With Non-squamous Histology Who Have Mutations and/or Co-mutations in STK11, KEAP1, or KRAS

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms