A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

NCT ID: NCT06112418

The TRANSFORM trial is a research study designed to compare two different approaches to help prevent heart problems in people who are at higher risk but do not currently have any symptoms of heart ...

Recruiting

Phase: NA Conditions: Diabetes Mellitus, Type 2, Metabolic Syndrome +1 more

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT ID: NCT06312176

This clinical trial is studying a new treatment option for patients with a specific type of breast cancer called hormone receptor positive and HER2 negative (HR+/HER2-). The researchers want to see...

Recruiting

Phase: PHASE3 Conditions: Breast Neoplasms

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

NCT ID: NCT06393374

This clinical trial is studying a new treatment for patients with triple-negative breast cancer (TNBC) who did not completely respond to earlier treatment before surgery. The researchers want to fi...

Recruiting

Phase: PHASE3 Conditions: Triple-Negative Breast Cancer

A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).

NCT ID: NCT06551324

This clinical trial, called MEVPRO-1, is looking at a new medicine called PF-06821497 (Mevrometostat) to see if it can help men with metastatic castrate-resistant prostate cancer (mCRPC) who have p...

Recruiting

Phase: PHASE3 Conditions: Metastatic Castrate Resistant Prostate Cancer (mCRPC)

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

NCT ID: NCT06629779

This clinical trial is studying a new drug called PF-06821497 (also known as Mevrometostat) to see if it works better when combined with another medication called enzalutamide for men with metastat...

Recruiting

Phase: PHASE3 Conditions: Metastatic Castration-Resistant Prostate Cancer

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

NCT ID: NCT06841354

This clinical trial is studying the effectiveness of a drug called sacituzumab tirumotecan (also known as Sac-TMT) both on its own and in combination with another drug called pembrolizumab for trea...

Recruiting

Phase: PHASE3 Conditions: Triple Negative Breast Neoplasms

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

NCT ID: NCT06252649

This clinical trial is studying a new treatment approach for patients with metastatic colorectal cancer that has a specific genetic change known as the KRAS p.G12C mutation. Researchers want to see...

Recruiting

Phase: PHASE3 Conditions: Metastatic Colorectal Cancer

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

NCT ID: NCT06632444

The LIVERAGE™ clinical trial is studying a medication called survodutide to see if it can help adults with a liver disease known as Metabolic Dysfunction Associated Steatohepatitis (MASH) who also ...

Recruiting

Phase: PHASE3 Conditions: Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis (MASH)

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

NCT ID: NCT04743141

This clinical trial is studying the long-term safety of a medication called rimegepant for treating migraines in children and teenagers aged 6 to 17 years old. The goal is to see how well rimegepan...

Recruiting

Phase: PHASE3 Conditions: Acute Treatment of Migraine

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

NCT ID: NCT06585787

The ADEPT-4 clinical trial is studying a new treatment called KarXT for individuals with Alzheimer's Disease (AD) who are experiencing psychosis, which includes symptoms like hallucinations or delu...

Recruiting

Phase: PHASE3 Conditions: Alzheimer Disease

A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

NCT ID: NCT06880744

This clinical trial is looking at how well a medication called risankizumab works compared to another medication called vedolizumab in treating adults with moderate to severe ulcerative colitis (UC...

Recruiting

Phase: PHASE3 Conditions: Ulcerative Colitis

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

NCT ID: NCT07011745

This clinical trial, called ADAGIO-2, is investigating a new treatment called KarXT + KarX-EC for adults with Alzheimer's disease who experience agitation. Agitation can include feelings of restles...

Recruiting

Phase: PHASE3 Conditions: Alzheimer Disease

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

NCT ID: NCT07064473

This clinical trial is studying whether a new medicine called vicadrostat, when taken together with an existing diabetes medicine called empagliflozin, can help lower the risk of heart problems in ...

Recruiting

Phase: PHASE3 Conditions: Hypertension, Diabetes Mellitus, Type 2 +1 more

Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer

NCT ID: NCT04464226

This clinical trial is studying the continuation of a treatment called darolutamide for men with cancer who have already participated in previous studies using this medication. The goal is to provi...

Recruiting

Phase: PHASE3 Conditions: Cancer

Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis

NCT ID: NCT06846541

This clinical trial is studying a medication called ESK-001 to see how safe it is when taken for a long time by people with moderate to severe plaque psoriasis, a skin condition that causes red, sc...

Recruiting

Phase: PHASE3 Conditions: Psoriasis, Plaque Psoriasis +3 more

C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic HCV

NCT ID: NCT06868264

The C-BEYOND clinical trial is studying two different treatment options for adults with chronic Hepatitis C virus (HCV) infection: BEM/RZR and SOF/VEL. The main goal is to find out which treatment ...

Recruiting

Phase: PHASE3 Conditions: HEPATITIS C VIRUS CHRONIC INFECTION

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

NCT ID: NCT06598943

This clinical trial is looking at two medications, eltrekibart and mirikizumab, to see how safe and effective they are for adults with moderately to severely active ulcerative colitis (UC). Ulcerat...

Recruiting

Phase: PHASE2 Conditions: Ulcerative Colitis, Ulcerative Colitis Chronic

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

NCT ID: NCT05395481

This clinical trial is studying a new medication called LY3849891 to see if it is safe and how well it works for people with nonalcoholic fatty liver disease, particularly those who have a specific...

Recruiting

Phase: PHASE1 Conditions: Metabolic Dysfunction-Associated Steatohepatitis (MASH), Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

NCT ID: NCT06245408

This clinical trial is studying a new treatment called dazodalibep for patients with Sjögren's Syndrome (SS), specifically those who experience moderate to severe symptoms. The main goal is to see ...

Recruiting

Phase: PHASE3 Conditions: Sjögren's Syndrome (SS)

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Clinical Trials in Chandler, Arizona

125 Active Trials Found in Chandler

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer

Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis

C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic HCV

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State