Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus Erythematosus

NCT ID: NCT05039840

This clinical trial is studying a new treatment called Frexalimab (SAR441344) for adults aged 18 to 70 who have an active condition known as Systemic Lupus Erythematosus (SLE). The trial will compa...

Recruiting

Phase: PHASE2 Conditions: Systemic Lupus Erythematosus

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

NCT ID: NCT05395481

This clinical trial is studying a new medication called LY3849891 to see if it is safe and how well it works for people with nonalcoholic fatty liver disease, particularly those who have a specific...

Recruiting

Phase: PHASE1 Conditions: Metabolic Dysfunction-Associated Steatohepatitis (MASH), Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)

Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)

NCT ID: NCT05555732

This clinical trial, called TROPION-Lung07, is investigating a new treatment approach for patients with advanced non-small cell lung cancer (NSCLC) that has spread to other parts of the body. The s...

Recruiting

Phase: PHASE3 Conditions: Metastatic Non Small Cell Lung Cancer

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

NCT ID: NCT06104124

This clinical trial is studying a new medication called dazodalibep to see how well it works for people with Sjögren's syndrome (SS), especially those who have moderate to severe symptoms affecting...

Recruiting

Phase: PHASE3 Conditions: Sjogren's Syndrome

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents

NCT ID: NCT06120491

This clinical trial is investigating a new treatment called Saruparib (AZD5305) for men with metastatic castration-sensitive prostate cancer, which means their cancer has spread but still responds ...

Recruiting

Phase: PHASE3 Conditions: Metastatic Castration-Sensitive Prostate Cancer

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

NCT ID: NCT06252649

This clinical trial is studying a new treatment approach for patients with metastatic colorectal cancer that has a specific genetic change known as the KRAS p.G12C mutation. Researchers want to see...

Recruiting

Phase: PHASE3 Conditions: Metastatic Colorectal Cancer

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NCT ID: NCT06528314

This clinical trial is studying a new medication called efruxifermin (EFX) for people with compensated cirrhosis caused by nonalcoholic steatohepatitis (NASH) or metabolic dysfunction-associated st...

Recruiting

Phase: PHASE3 Conditions: NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

NCT ID: NCT06112418

The TRANSFORM trial is a research study designed to compare two different approaches to help prevent heart problems in people who are at higher risk but do not currently have any symptoms of heart ...

Recruiting

Phase: NA Conditions: Diabetes Mellitus, Type 2, Metabolic Syndrome +1 more

Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression

NCT ID: NCT06419608

This clinical trial is studying a new treatment called BHV-7000 for people with Major Depressive Disorder (MDD). The goal is to see how well this treatment works and how safe it is for individuals ...

Recruiting

Phase: PHASE2 Conditions: Major Depressive Disorder

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

NCT ID: NCT06562543

This clinical trial is investigating the safety and effectiveness of a medication called fruquintinib in minority groups, specifically Black or African American and Hispanic or Latino adults, who h...

Recruiting

Phase: PHASE4 Conditions: Colorectal Cancer

Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy

NCT ID: NCT06568042

This clinical trial is looking at a new treatment called LY3848575 to see how safe and effective it is for people experiencing painful nerve pain, specifically in the feet and legs. This kind of pa...

Recruiting

Phase: PHASE2 Conditions: Neuropathic Pain, Distal Sensory Polyneuropathy

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

NCT ID: NCT06585787

The ADEPT-4 clinical trial is studying a new treatment called KarXT for individuals with Alzheimer's Disease (AD) who are experiencing psychosis, which includes symptoms like hallucinations or delu...

Recruiting

Phase: PHASE3 Conditions: Alzheimer Disease

A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes

NCT ID: NCT06603571

This clinical trial is studying a new treatment called LY3841136, both alone and with another medication called Tirzepatide, to help manage weight in adults who are overweight or have obesity and a...

Recruiting

Phase: PHASE2 Conditions: Obesity, Overweight

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

NCT ID: NCT06632444

The LIVERAGE™ clinical trial is studying a medication called survodutide to see if it can help adults with a liver disease known as Metabolic Dysfunction Associated Steatohepatitis (MASH) who also ...

Recruiting

Phase: PHASE3 Conditions: Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis (MASH)

A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)

NCT ID: NCT06653153

The TRAILRUNNER-ALZ 3 study is looking at a new drug called Remternetug (LY3372993) to see if it can help people with early Alzheimer's disease. The main goal of the trial is to find out if this dr...

Recruiting

Phase: PHASE3 Conditions: Alzheimer's Disease

Safety and Efficacy of EIK1001-006 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

NCT ID: NCT06697301

This clinical trial is studying a new treatment combination for patients with advanced melanoma, a serious skin cancer, who are eligible for a standard therapy called Pembrolizumab. The trial aims ...

Recruiting

Phase: PHASE2 Conditions: Advanced Melanoma

Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

NCT ID: NCT06750289

This clinical trial is studying a medication called benralizumab to see how well it works and how safe it is for people with uncontrolled eosinophilic asthma. Eosinophilic asthma is a type of asthm...

Recruiting

Phase: PHASE3 Conditions: Eosinophilic Asthma

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

NCT ID: NCT06937229

The ADAGIO-3 study is a clinical trial focused on testing a new treatment for agitation in people with Alzheimer’s Disease. This trial will specifically look at the long-term effects and safety of ...

Not yet recruiting

Phase: PHASE3 Conditions: Alzheimer Disease, Agitation

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

NCT ID: NCT03907046

This clinical trial is looking at whether a medication called apixaban is better than aspirin for preventing strokes and death in patients who have recently had a type of brain bleed known as intra...

Recruiting

Phase: PHASE3 Conditions: Atrial Fibrillation, Intracerebral Hemorrhage

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Clinical Trials in Chandler, Arizona

121 Active Trials Found in Chandler

Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus Erythematosus

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)

Safety and Efficacy of EIK1001-006 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery