Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)

NCT ID: NCT04938817

This clinical trial is exploring new treatment options for patients with extensive-stage small cell lung cancer (ES-SCLC) who need a second line of therapy after their initial treatment. The study ...

Recruiting

Phase: PHASE1 Conditions: Small Cell Lung Carcinoma

A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma

NCT ID: NCT05572515

This clinical trial is studying a new treatment called teclistamab for patients with relapsed or refractory multiple myeloma, which means their cancer has returned or has not responded to previous ...

Recruiting

Phase: PHASE3 Conditions: Relapsed or Refractory Multiple Myeloma

A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome

NCT ID: NCT05754957

This clinical trial is studying a medication called milvexian to see if it can help reduce the risk of serious heart problems in patients who have recently experienced an acute coronary syndrome (A...

Recruiting

Phase: PHASE3 Conditions: Acute Coronary Syndrome

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

NCT ID: NCT06119581

This clinical trial is investigating whether a new drug called LY3537982, combined with standard cancer treatments like immunotherapy and chemotherapy, is more effective for patients with advanced ...

Recruiting

Phase: PHASE3 Conditions: Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

NCT ID: NCT06283966

This clinical trial is studying a new inhaler that combines three medications—budesonide, glycopyrronium, and formoterol—to see how well it works in improving heart and lung health in people with C...

Recruiting

Phase: PHASE3 Conditions: COPD (Chronic Obstructive Pulmonary Disease)

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT ID: NCT06312176

This clinical trial is studying a new treatment option for patients with a specific type of breast cancer called hormone receptor positive and HER2 negative (HR+/HER2-). The researchers want to see...

Recruiting

Phase: PHASE3 Conditions: Breast Neoplasms

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

NCT ID: NCT06667908

This clinical trial is studying a new treatment approach for patients with locally advanced non-small cell lung cancer (NSCLC) that cannot be surgically removed. The researchers want to see if addi...

Recruiting

Phase: PHASE2 Conditions: Carcinoma, Non-Small-Cell Lung

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

NCT ID: NCT05712200

The LILAC-TIMI 76 clinical trial is investigating the safety and effectiveness of a drug called abelacimab for patients with Atrial Fibrillation (AF) who are at high risk for blood clots but cannot...

Recruiting

Phase: PHASE3 Conditions: Atrial Fibrillation (AF)

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

NCT ID: NCT06241456

This clinical trial is studying a new treatment called FT825 (also known as ONO-8250), which is a type of therapy that uses specially modified cells to fight advanced solid tumors that are HER2-pos...

Recruiting

Phase: PHASE1 Conditions: Advanced Solid Tumor

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

NCT ID: NCT06383390

The TRIUMPH-OUTCOMES study is looking at a new treatment called retatrutide, which is given once a week, to see if it can help reduce serious heart problems and protect kidney function in adults wh...

Recruiting

Phase: PHASE3 Conditions: Chronic Kidney Disease (CKD), Atherosclerotic Cardiovascular Disease (ASCVD)

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis

NCT ID: NCT06624228

This clinical trial is studying the effectiveness and safety of a medication called bimekizumab for adults with active psoriatic arthritis (PsA). PsA is a type of arthritis that can cause joint pai...

Recruiting

Phase: PHASE3 Conditions: Psoriatic Arthritis

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

NCT ID: NCT06864026

The TOGETHER AMPLIFY-PsA clinical trial is studying how effective the medication tirzepatide is when added to ixekizumab treatment for people with active psoriatic arthritis (PsA) who are also over...

Recruiting

Phase: PHASE4 Conditions: Psoriatic Arthritis, Overweight or Obesity

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

NCT ID: NCT04879329

This clinical trial is testing a new treatment for patients with urothelial cancer that shows a specific marker called HER2. The study is looking at whether a drug called disitamab vedotin, either ...

Recruiting

Phase: PHASE2 Conditions: Urothelial Carcinoma

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

NCT ID: NCT06104124

This clinical trial is studying a new medication called dazodalibep to see how well it works for people with Sjögren's syndrome (SS), especially those who have moderate to severe symptoms affecting...

Recruiting

Phase: PHASE3 Conditions: Sjogren's Syndrome

Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

NCT ID: NCT06417775

This clinical trial is studying a medication called ubrogepant to see if it is safe and effective for treating menstrual migraines in adult women. A menstrual migraine is a severe headache that occ...

Recruiting

Phase: PHASE3 Conditions: Migraine

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

NCT ID: NCT06623422

This clinical trial is studying whether a combination of two treatments, pembrolizumab and V940, can help people with non-small cell lung cancer (NSCLC) stay cancer-free for a longer time after sur...

Recruiting

Phase: PHASE3 Conditions: Carcinoma, Non-Small-Cell Lung

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

NCT ID: NCT06677060

This clinical trial is studying the effects of a medication called Baxdrostat combined with Dapagliflozin on heart failure and cardiovascular death in adults aged 40 and older who have type 2 diabe...

Recruiting

Phase: PHASE3 Conditions: Heart Failure

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

NCT ID: NCT03072927

This clinical trial is studying a procedure called MILD® (Minimally Invasive Lumbar Decompression) for patients with a condition known as lumbar spinal stenosis, which means there is pressure on th...

Recruiting

Conditions: Lumbar Spinal Stenosis

ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)

NCT ID: NCT04883905

The ELEVATE trial is a global registry aimed at understanding the experiences of patients with Acute Hepatic Porphyria (AHP), a rare genetic condition that affects the liver. This study will gather...

Recruiting

Conditions: Acute Hepatic Porphyria

Prospective Case Collection Study for New Mammography Technologies

NCT ID: NCT05199701

This clinical trial is looking at new mammography technologies to see how safe and effective they are for screening and diagnosing breast cancer. Researchers want to understand how well this new te...

Recruiting

Phase: NA Conditions: Mammography

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Clinical Trials in Gilbert, Arizona

153 Active Trials Found in Gilbert

Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)

A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma

A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)

Prospective Case Collection Study for New Mammography Technologies