A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis

NCT ID: NCT06407934

This clinical trial is designed to evaluate how well two different doses of a medication called amlitelimab work for people aged 12 years and older with moderate-to-severe atopic dermatitis, a cond...

Recruiting

Phase: PHASE3 Conditions: Dermatitis Atopic

A Study of Apremilast in Pediatric Participants in Children With Mild to Moderate Plaque Psoriasis

NCT ID: NCT06088199

This clinical trial is studying a medication called apremilast to see how safe it is for children aged 6 to 17 who have mild to moderate plaque psoriasis, a skin condition that causes red, scaly pa...

Recruiting

Phase: PHASE3 Conditions: Plaque Psoriasis

An Internet-based Program to Help Cancer Survivors Manage Pain

NCT ID: NCT04462302

This clinical trial is exploring a new online program designed to help cancer survivors manage pain. Researchers want to see if this internet-based pain coping skills program, along with regular ca...

Recruiting

Phase: NA Conditions: Cancer

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

NCT ID: NCT05174169

This clinical trial, titled "Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease," is looking at how to best choose chemotherapy treatments for patients with Stage III colon cancer ...

Recruiting

Phase: PHASE2 Conditions: Stage III Colon Cancer

Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

NCT ID: NCT06538038

This clinical trial is studying how well a medication called osimertinib, with or without chemotherapy, works for patients with advanced non-small cell lung cancer (NSCLC) that has a specific mutat...

Recruiting

Conditions: Non Small Cell Lung Cancer, Stage IV Lung Cancer +2 more

A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult Patients With Moderate to Severe Hidradenitis Suppurativa

NCT ID: NCT06799000

This clinical trial is investigating a new treatment called remibrutinib for adults with moderate to severe hidradenitis suppurativa (HS), a painful skin condition that causes lumps and sores. The ...

Recruiting

Phase: PHASE3 Conditions: Hidradenitis Suppurativa

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

NCT ID: NCT02523014

This clinical trial is investigating the effectiveness of four different medications—vismodegib, GSK2256098 (a FAK inhibitor), capivasertib, and abemaciclib—in treating patients with progressive me...

Recruiting

Phase: PHASE2 Conditions: Intracranial Meningioma, Recurrent Meningioma +1 more

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

NCT ID: NCT03609216

This clinical trial is looking at how well two chemotherapy drugs, gemcitabine and cisplatin, work for treating patients with a type of bladder cancer called muscle-invasive urothelial carcinoma. T...

Recruiting

Phase: PHASE2 Conditions: Infiltrating Bladder Urothelial Carcinoma, Stage II Bladder Urothelial Carcinoma +1 more

Genetic Testing in Guiding Treatment for Patients With Brain Metastases

NCT ID: NCT03994796

This clinical trial is exploring how genetic testing can help doctors choose the best treatments for patients with solid tumors that have spread to the brain. Researchers are particularly intereste...

Recruiting

Phase: PHASE2 Conditions: Metastatic Malignant Solid Neoplasm, Metastatic Malignant Neoplasm in the Brain +5 more

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

NCT ID: NCT04242095

**Trial Summary: Collection of Research Data and Samples from Patients Experiencing Immunotherapy Side Effects** This clinical trial is focused on gathering information and samples from patients w...

Recruiting

Conditions: Malignancy

Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer

NCT ID: NCT04340141

This clinical trial is studying how effective chemotherapy is when given both before and after surgery for patients with removable pancreatic cancer, compared to giving chemotherapy only after surg...

Recruiting

Phase: PHASE3 Conditions: Pancreatic Cancer, Resectable Pancreatic Adenocarcinoma +1 more

Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

NCT ID: NCT04379570

This clinical trial is looking at how an additional support program, which includes text message reminders and phone counseling, can help breast cancer patients stick to their prescribed medication...

Recruiting

Phase: PHASE3 Conditions: Anatomic Stage III Breast Cancer AJCC v8, Invasive Breast Carcinoma +7 more

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

NCT ID: NCT05008848

This clinical trial, titled "Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program," is designed to help cancer survivors who smoke cigarettes. The study is comparing two methods to su...

Recruiting

Phase: PHASE3 Conditions: Cigarette Smoking-Related Carcinoma

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation

NCT ID: NCT05610163

This clinical trial is investigating whether adding an anti-cancer drug called irinotecan to the standard chemotherapy treatment (FOLFOX) can improve outcomes for patients with advanced-stage recta...

Recruiting

Phase: PHASE2 Conditions: Stage III Rectal Cancer AJCC v8, Stage II Rectal Cancer AJCC v8 +1 more

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

NCT ID: NCT06632327

This clinical trial is exploring the best way to treat patients with stage II to IIIB non-small cell lung cancer (NSCLC) that can be surgically removed. The study compares two treatment methods: on...

Recruiting

Phase: PHASE3 Conditions: Stage IIIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8 +2 more

Testing Low Dose Tamoxifen for Invasive Breast Cancer, the (LoTam) Trial

NCT ID: NCT06671912

The LoTam Trial is a study looking at how effective a low dose of tamoxifen is for treating early-stage breast cancer in post-menopausal women. Tamoxifen is a medication that blocks estrogen, a hor...

Recruiting

Phase: PHASE3 Conditions: Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage 0 Breast Cancer AJCC v8 +3 more

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

NCT ID: NCT05879926

This clinical trial is investigating whether adding chemotherapy to ovarian function suppression and hormone therapy can help prevent breast cancer from returning in premenopausal women with early-...

Recruiting

Phase: PHASE3 Conditions: Breast Cancer

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

NCT ID: NCT05147220

This clinical trial is investigating the effectiveness and safety of a new medication called remibrutinib compared to an existing treatment, teriflunomide, for people with relapsing multiple sclero...

Recruiting

Phase: PHASE3 Conditions: Relapsing Multiple Sclerosis

Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne

NCT ID: NCT04582383

This clinical trial is studying the effectiveness of two different treatments for acne in women: spironolactone and doxycycline. Acne is a common skin condition that can cause inflammation and disc...

Recruiting

Phase: PHASE4 Conditions: Acne

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

NCT ID: NCT05561387

This clinical trial is investigating different combinations of drugs to treat newly diagnosed multiple myeloma in patients who cannot undergo a stem cell transplant due to their health condition. T...

Recruiting

Phase: PHASE3 Conditions: Plasma Cell Myeloma

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Clinical Trials in Fort Smith, Arkansas

83 Active Trials Found in Fort Smith

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis

A Study of Apremilast in Pediatric Participants in Children With Mild to Moderate Plaque Psoriasis

An Internet-based Program to Help Cancer Survivors Manage Pain

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult Patients With Moderate to Severe Hidradenitis Suppurativa

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

Genetic Testing in Guiding Treatment for Patients With Brain Metastases

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer

Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

Testing Low Dose Tamoxifen for Invasive Breast Cancer, the (LoTam) Trial

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment