Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

NCT ID: NCT02523014

This clinical trial is investigating the effectiveness of four different medications—vismodegib, GSK2256098 (a FAK inhibitor), capivasertib, and abemaciclib—in treating patients with progressive me...

Recruiting

Phase: PHASE2 Conditions: Intracranial Meningioma, Recurrent Meningioma +1 more

Clinical Study of Edwards Cardioband FIT Valve Repair System

NCT ID: NCT03382457

The clinical trial is studying a new device called the Edwards Cardioband FIT Valve Repair System, which is designed to help treat a heart condition known as tricuspid regurgitation. This condition...

Recruiting

Phase: NA Conditions: Tricuspid Regurgitation

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

NCT ID: NCT03435796

This clinical trial is focused on following up with patients who have received a special treatment called gene-modified T cell therapy for cancer. The study aims to gather information about the lon...

Recruiting

Phase: PHASE2 Conditions: Neoplasms

OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps

NCT ID: NCT03747458

This clinical trial is studying a new treatment called OPN-375 for adolescents aged 12 to 17 who have bilateral nasal polyps, which are growths in the nasal passages that can cause breathing diffic...

Recruiting

Phase: PHASE3 Conditions: Bilateral Nasal Polyposis

Genetic Testing in Guiding Treatment for Patients With Brain Metastases

NCT ID: NCT03994796

This clinical trial is exploring how genetic testing can help doctors choose the best treatments for patients with solid tumors that have spread to the brain. Researchers are particularly intereste...

Recruiting

Phase: PHASE2 Conditions: Metastatic Malignant Solid Neoplasm, Metastatic Malignant Neoplasm in the Brain +5 more

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

NCT ID: NCT04242095

**Trial Summary: Collection of Research Data and Samples from Patients Experiencing Immunotherapy Side Effects** This clinical trial is focused on gathering information and samples from patients w...

Recruiting

Conditions: Malignancy

Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

NCT ID: NCT04379570

This clinical trial is looking at how an additional support program, which includes text message reminders and phone counseling, can help breast cancer patients stick to their prescribed medication...

Recruiting

Phase: PHASE3 Conditions: Anatomic Stage III Breast Cancer AJCC v8, Invasive Breast Carcinoma +7 more

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

NCT ID: NCT04803201

This clinical trial is looking at whether adding two new treatments, duvelisib or CC-486, to the standard chemotherapy for certain types of peripheral T-cell lymphoma can improve outcomes for patie...

Recruiting

Phase: PHASE2 Conditions: Angioimmunoblastic T-cell Lymphoma, Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma +5 more

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

NCT ID: NCT04877288

This clinical trial is looking at how well a new medication called belatacept works for teenagers aged 12 to under 18 who have received a kidney transplant. The study compares the effects of switch...

Recruiting

Phase: PHASE3 Conditions: Renal Allograft Recipients

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

NCT ID: NCT04939090

This clinical trial is studying two medications, olanzapine and megestrol acetate, to see which one is more effective at helping cancer patients with advanced disease who are experiencing a loss of...

Recruiting

Phase: PHASE3 Conditions: Hematopoietic and Lymphoid Cell Neoplasm, Advanced Malignant Solid Neoplasm +1 more

A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3)

NCT ID: NCT05026866

The TRAILBLAZER-ALZ 3 study is a clinical trial focused on testing the safety and effectiveness of a drug called donanemab in people who have early signs of Alzheimer's disease but do not yet have ...

Recruiting

Phase: PHASE3 Conditions: Alzheimer Disease

Duloxetine RCT on Postop TKA Outcomes

NCT ID: NCT05086393

This clinical trial is studying the effects of a medication called duloxetine on patients who are having total knee replacement surgery, specifically looking at how it affects pain, recovery, and t...

Recruiting

Phase: PHASE4 Conditions: Pain, Postoperative, Total Knee Arthroplasty

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

NCT ID: NCT05647265

This clinical trial is looking at how well immunotherapy, specifically a combination of two medications called nivolumab and ipilimumab, works when given before surgery for patients with a specific...

Recruiting

Phase: PHASE2 Conditions: Pleural Biphasic Mesothelioma, Pleural Sarcomatoid Mesothelioma

SMARTer Weight Loss Management

NCT ID: NCT05861973

The SMARTer Weight Loss Management trial is a research study looking at different ways to help people lose weight, specifically for those struggling with obesity. The trial compares a new approach ...

Recruiting

Phase: NA Conditions: Obesity

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

NCT ID: NCT05976763

This clinical trial is studying the best way to use the drug zanubrutinib for older patients with mantle cell lymphoma (MCL) who have not been treated before. Specifically, researchers want to find...

Recruiting

Phase: PHASE3 Conditions: Mantle Cell Lymphoma

Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab

NCT ID: NCT06107413

This clinical trial is studying a new treatment for adults with unresectable metastatic colorectal cancer, which means their cancer cannot be surgically removed and has spread to other parts of the...

Recruiting

Phase: PHASE2 Conditions: Unresectable Metastatic Colorectal Cancer

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

NCT ID: NCT06132113

The DAREON™-7 trial is studying a new medicine called BI 764532, which is given along with standard chemotherapy to see how well it works for people with advanced neuroendocrine cancers. This study...

Recruiting

Phase: PHASE1 Conditions: Neuroendocrine Neoplasms

Foundation for Sarcoidosis Research Advanced Cures Registry (FSR-SARC Registry)

NCT ID: NCT06234384

The Foundation for Sarcoidosis Research Advanced Cures Registry (FSR-SARC Registry) is a study aimed at understanding sarcoidosis, a condition that causes inflammation in various parts of the body....

Recruiting

Conditions: Sarcoidosis

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

NCT ID: NCT06395415

This clinical trial is studying a new mobile health program designed to help young adults who use electronic cigarettes (also known as e-cigarettes or ENDS) and are interested in quitting or reduci...

Recruiting

Phase: NA Conditions: Cigarette Smoking, Tobacco Products +1 more

Phase IIa Study Evaluating AZD7798 in Crohn's Disease

NCT ID: NCT06450197

This clinical trial is studying a new treatment called AZD7798 for people with moderate to severe Crohn's disease, which is a chronic condition that causes inflammation in the digestive tract. The ...

Recruiting

Phase: PHASE2 Conditions: Moderate to Severe Crohn's Disease

Main Menu

Clinical Trials in Chicago, Illinois

2302 Active Trials Found in Chicago

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Clinical Study of Edwards Cardioband FIT Valve Repair System

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps

Genetic Testing in Guiding Treatment for Patients With Brain Metastases

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3)

Duloxetine RCT on Postop TKA Outcomes

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

SMARTer Weight Loss Management

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

Foundation for Sarcoidosis Research Advanced Cures Registry (FSR-SARC Registry)

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

Phase IIa Study Evaluating AZD7798 in Crohn's Disease