Clinical Trials for Advanced Cancer

Find clinical trials for advanced cancer. Discover research opportunities and treatment options in your area.

112 Active Trials Found

Showing 112 trials on this page

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Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

NCT ID: NCT05735080

This clinical trial is studying a new oral medication called INX-315, which is being developed to treat advanced cancers, specifically hormone receptor-positive breast cancer and certain types of o...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Detroit, Michigan, United States +12 more

Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1

NCT ID: NCT03785249

The KRYSTAL-1 clinical trial is studying a new drug called MRTX849 (also known as adagrasib) in patients with advanced cancer that has a specific genetic change known as the KRAS G12C mutation. Thi...

Recruiting

Phase: PHASE1 Type: interventional Locations: Minneapolis, Minnesota, United States, Orange, California, United States +311 more

Study of HC006 in Combination With a PD-1 Inhibitor in Patients With Advanced Solid Tumors

NCT ID: NCT06963814

This clinical trial is studying a new treatment called HC006 combined with another medication known as a PD-1 inhibitor for patients with advanced solid tumors, which are types of cancer that have ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Shanghai, Shanghai, China

Analysis of PD-L1, TMB, MSI and ctDNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer.

NCT ID: NCT06227728

This clinical trial is looking at how changes in certain blood markers can help doctors predict how well patients with advanced-stage cancer respond to a type of treatment called immunotherapy. Spe...

Recruiting

Type: observational Locations: Ho Chi Minh City, , Vietnam, Ho Chi Minh City, Hồ Chí Minh, Vietnam +1 more

Practical Geriatric Assessment (PGA) Implementation Strategies and Correlative Evaluations (PACE-70)

NCT ID: NCT06870617

The PACE-70 clinical trial is studying a method called the Practical Geriatric Assessment (PGA) to help doctors provide better care for older adults with advanced cancer. This method aims to improv...

Recruiting

Type: observational Locations: Philadelphia, Pennsylvania, United States, Lancaster, Pennsylvania, United States +1 more

Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors

NCT ID: NCT05270213

This clinical trial is studying a new treatment called RBS2418 for patients with advanced cancer that cannot be surgically removed or has come back after treatment. RBS2418 is designed to help the ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Columbus, Ohio, United States, New Orleans, Louisiana, United States +18 more

Psilocybin in Cancer Pain Study

NCT ID: NCT06001749

The Psilocybin in Cancer Pain Study is looking at whether a treatment involving psilocybin, a compound found in certain mushrooms, can help relieve severe pain in patients with advanced cancer who ...

Recruiting

Phase: PHASE2 Type: interventional Locations: Boston, Massachusetts, United States, Boston, Massachusetts, United States +2 more

Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)

NCT ID: NCT05853575

The KRYSTAL 21 trial is studying a medication called adagrasib, which is being tested in two different doses to see which one works better for patients with advanced non-small cell lung cancer (NSC...

Recruiting

Phase: PHASE2 Type: interventional Locations: Bangkok, , Thailand, Valencia, , Spain +259 more

Trastuzumab Plus Chemotherapy vs Chemotherapy Alone in First-line HER2 Positive Advanced Biliary Tract Cancer Patients

NCT ID: NCT07062263

This clinical trial is studying a new treatment approach for people with advanced biliary tract cancer, a type of cancer that starts in the bile ducts or gallbladder and has spread or cannot be rem...

Recruiting

Phase: PHASE3 Type: interventional Locations: Mumbai, Maharashtra, India, Bhubaneswar, Odisha, India +4 more

Routine Evaluation of People Living With Cancer

NCT ID: NCT04406662

This clinical trial, titled "Routine Evaluation of People Living With Cancer," is focused on understanding the complex needs of individuals with incurable cancer. Researchers want to gather detaile...

Recruiting

Type: observational Locations: Edinburgh, , United Kingdom

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

NCT ID: NCT05891171

This clinical trial is studying a new treatment called AB598 for patients with advanced cancers, including types like bladder, cervical, lung, and breast cancer, among others. The main goal is to s...

Recruiting

Phase: PHASE1 Type: interventional Locations: Rochester, Minnesota, United States, New Orleans, Louisiana, United States +25 more

FS222 First in Human Study in Patients With Advanced Malignancies

NCT ID: NCT04740424

The FS222 clinical trial is a first-in-human study exploring a new treatment called FS222 for adults with advanced cancer that has not responded to standard therapies. This study aims to understand...

Recruiting

Phase: PHASE1 Type: interventional Locations: Madrid, , Spain, Valencia, , Spain +21 more

First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer

NCT ID: NCT06239467

This clinical trial is studying a new treatment called OKI-219 for patients with advanced solid tumors, including advanced breast cancer. The trial is divided into two parts. In the first part, res...

Recruiting

Phase: PHASE1 Type: interventional Locations: Boston, Massachusetts, United States, Nice, , France +37 more

A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies

NCT ID: NCT06120075

This clinical trial is investigating a new treatment called AB801 for patients with advanced cancer. The main goal is to find out how safe AB801 is and determine the best dose to use in future stud...

Recruiting

Phase: PHASE1 Type: interventional Locations: Atlanta, Georgia, United States, Philadelphia, Pennsylvania, United States +12 more

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

NCT ID: NCT03175224

The APL-101 clinical trial is exploring a new treatment for patients with advanced lung cancer, specifically those with certain genetic changes called c-Met Exon 14 skipping mutations or MET amplif...

Recruiting

Phase: PHASE2 Type: interventional Locations: Rochester, Minnesota, United States, Madison, Wisconsin, United States +114 more

A Study of IMC-002 in Patients With Advanced Cancer Failed to Standard Therapy

NCT ID: NCT05276310

This clinical trial is studying a new treatment called IMC-002 for patients with advanced cancer who have not responded to standard therapies. It aims to find out how safe the treatment is, how wel...

Recruiting

Phase: PHASE1 Type: interventional Locations: Seoul, , Korea, Republic Of, Seoul, , Korea, Republic Of +2 more

A Study of MGC026 in Participants With Advanced Solid Tumors

NCT ID: NCT06242470

This clinical trial is investigating a new treatment called MGC026 for adults with advanced solid tumors, which are types of cancer that have spread or cannot be removed through surgery. The study ...

Recruiting

Phase: PHASE1 Type: interventional Locations: Houston, Texas, United States, Los Angeles, California, United States +10 more

Kinesio-Taping vs. Usual Care for Malignant Bowel Obstruction With Ascites

NCT ID: NCT07023042

This clinical trial is studying whether abdominal Kinesio-taping can help relieve symptoms like pain, bloating, and nausea in adults with advanced cancer who have malignant bowel obstruction and as...

Recruiting

Phase: NA Type: interventional Locations: Taipei, , Taiwan

Personalized Neoantigen Peptide Vaccines for Solid Tumors

NCT ID: NCT07002203

This clinical trial is exploring a new personalized cancer treatment called a neoantigen peptide vaccine for patients with solid tumors, which are types of cancer that form in tissues or organs. Th...

Recruiting

Phase: PHASE1 Type: interventional Locations: Bangkok, , Thailand, Bangkok, , Thailand

Evaluating Disparities in Precision Oncology

NCT ID: NCT06081517

This clinical trial, called "Evaluating Disparities in Precision Oncology," is focused on understanding how different factors, like genetics and social background, affect the treatment of metastati...

Recruiting

Type: observational Locations: Indianapolis, Indiana, United States

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