Clinical Trials for AL Amyloidosis

Evaluation of Skin Tests in Biotherapy Allergies

NCT ID: NCT06971848

This clinical trial, titled "Evaluation of Skin Tests in Biotherapy Allergies," is studying how to better identify allergic reactions in patients receiving certain biotherapy treatments. Biotherapi...

Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial

NCT ID: NCT05898646

The EMILIA Trial is studying how different lengths of maintenance therapy with a medication called daratumumab can help patients with AL amyloidosis live longer after their initial treatment. Maint...

Teclistamab in Previously Treated AL Amyloidosis

NCT ID: NCT06935162

This clinical trial is studying a new treatment called teclistamab for patients with AL Amyloidosis who have already received other therapies. AL Amyloidosis is a condition where abnormal proteins ...

Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL Amyloidosis

NCT ID: NCT05184088

This clinical trial is studying the effectiveness of a special imaging technique called PET (Positron Emission Tomography) using a substance called [18F]Florbetaben. The goal is to see if this imag...

Novel Imaging Tools in Newly-diagnosed Patients With Cardiac AL Amyloidosis

NCT ID: NCT04392960

This clinical trial is studying new imaging methods to better understand and monitor cardiac AL amyloidosis, a serious condition where abnormal proteins build up in the heart, affecting its functio...

Prospective Study of Teclistamab in the Treatment of Systemic AL Amyloidosis

NCT ID: NCT06699394

This clinical trial is studying a medication called teclistamab to see if it can help patients with systemic AL amyloidosis, a condition where abnormal proteins build up in organs and tissues. The ...

Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis

NCT ID: NCT04847453

This clinical trial is exploring a new treatment option for patients with relapsed or refractory light chain amyloidosis (AL amyloidosis), a condition where abnormal proteins build up in tissues an...

A Phase II Trial of Teclistamab in Participants With Previously Treated Immunoglobulin Light-chain (AL) Amyloidosis

NCT ID: NCT06649695

This clinical trial is studying a new treatment called teclistamab for people with a condition known as AL amyloidosis, which is a rare disease caused by abnormal protein buildup in the body. Speci...

The Norwegian Immunotherapy in Multiple Myeloma Study

NCT ID: NCT06855121

The Norwegian Immunotherapy in Multiple Myeloma Study is a research project looking at new treatments for multiple myeloma and related conditions, such as plasma cell leukemia and AL amyloidosis. T...

Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource

NCT ID: NCT01408225

The Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource is a clinical trial aimed at understanding and improving the lives of patients with certain blood disord...

BCMA/CD3 BiTE for RRAL or NDAL Amyloidosis With Insufficient Depth of Hematologic Response After Induction Therapy

NCT ID: NCT06769555

This clinical trial is studying a new treatment called CM-336 for patients with AL amyloidosis, a rare disease that can affect various organs in the body. The trial aims to see how effective and sa...

A EUropean REgistry and Sample Sharing networK to Promote the Diagnosis and Management of Light Chain Amyloidosis (EUREKA)

NCT ID: NCT06205953

The EUREKA trial is studying a condition called AL amyloidosis, which is a rare disease where abnormal proteins build up in the body and can cause serious health issues. This trial aims to create a...

Promoting Diagnosis and Management of AL in Italy (ProDigALIty)

NCT ID: NCT06383143

The ProDigALIty trial is investigating ways to improve the early diagnosis and management of AL amyloidosis, a condition where harmful proteins build up in the body. The study aims to create a netw...

A Registry of AL Amyloidosis (ReAL)

NCT ID: NCT04839003

The ReAL trial is a study aimed at creating a large registry of patients diagnosed with AL amyloidosis, a condition where abnormal proteins build up in the body and can cause various health problem...

Elranatamab in Patients with Relapsed or Refractory AL Amyloidosis

NCT ID: NCT06569147

This clinical trial is studying a new treatment called elranatamab for patients who have AL amyloidosis that has either returned after treatment (relapsed) or did not respond to previous therapies ...

Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

NCT ID: NCT05145816

This clinical trial is testing a new treatment called Belantamab mafodotin for people with a type of disease known as relapsed or refractory AL Amyloidosis. This condition occurs when abnormal prot...

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

NCT ID: NCT06022939

This clinical trial is comparing two treatment approaches for people who have just been diagnosed with AL amyloidosis, a condition where abnormal proteins build up in the body and can harm organs. ...

Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis

NCT ID: NCT05451771

This clinical trial is studying a combination of two medications, venetoclax and dexamethasone, in patients with a specific type of AL amyloidosis called t(11;14) positive relapsed or refractory li...

Isatuximab Plus Pomalidomide and Dexamethasone Association for Patients With AL Amyloidosis Not in VGPR or Better After Any Previous Therapy

NCT ID: NCT05066607

This clinical trial is studying a combination treatment using Isatuximab, Pomalidomide, and Dexamethasone for patients with AL Amyloidosis who have not improved significantly (not reached a very go...

Autologous Stem Cell Transplantation for Patients With AL Amyloidosis

NCT ID: NCT04210791