Clinical Trials for Alzheimer Disease

Find clinical trials for alzheimer disease. Discover research opportunities and treatment options in your area.

471 Active Trials Found

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A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

NCT ID: NCT07011732

The ADAGIO-1 clinical trial is a study looking at a new treatment called KarXT combined with KarX-EC for adults experiencing agitation due to Alzheimer’s disease. Agitation can include feelings of ...

Recruiting

Phase: PHASE3 Type: interventional Locations: Tulsa, Oklahoma, United States, Scottsdale, Arizona, United States +226 more

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

NCT ID: NCT06585787

The ADEPT-4 clinical trial is studying a new treatment called KarXT for individuals with Alzheimer's Disease (AD) who are experiencing psychosis, which includes symptoms like hallucinations or delu...

Recruiting

Phase: PHASE3 Type: interventional Locations: Columbus, Ohio, United States, Seoul, Korea, Republic Of +532 more

TMS Pilot in Early AD II

NCT ID: NCT06817902

This is a small, early-stage study testing whether a non-drug brain stimulation technique called intermittent theta burst stimulation (iTBS) can help with thinking and memory in people with early A...

Enrolling by invitation

Phase: NA Type: interventional Locations: Saint Paul, Minnesota, United States

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

NCT ID: NCT07011745

This clinical trial, called ADAGIO-2, is investigating a new treatment called KarXT + KarX-EC for adults with Alzheimer's disease who experience agitation. Agitation can include feelings of restles...

Recruiting

Phase: PHASE3 Type: interventional Locations: Atlanta, Georgia, United States, Seoul, Korea, Republic Of +234 more

Prediction and Prevention of Postoperative Mortality and Morbidity

NCT ID: NCT06042413

This clinical trial is focused on improving the health and safety of older adults who are facing major surgeries, particularly those with Alzheimer’s Disease (AD) or related conditions. The study a...

Not yet recruiting

Phase: NA Type: interventional Locations: Pittsburgh, Pennsylvania, United States

Synbiotic Formula (SCV09) in Alzheimer's Disease Patients

NCT ID: NCT06948929

This clinical trial, called the Synbiotic Formula (SCV09) study, is looking to see if a new combination of beneficial bacteria and nutrients can help improve behavior related to dementia in patient...

Recruiting

Phase: NA Type: interventional Locations: Shatin, Hong Kong

An Observational Study on Lecanemab Treatment for Early Alzheimer's Disease

NCT ID: NCT07153848

This clinical trial is studying how well certain blood tests can track the effects of a medicine called lecanemab in people with early Alzheimer's disease. Lecanemab is a treatment that aims to red...

Recruiting

Type: observational

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

NCT ID: NCT06808984

This clinical trial is looking at a new medication called BMS-986368, which aims to help reduce agitation in people with Alzheimer's disease. Agitation can include feelings of restlessness, irritab...

Recruiting

Phase: PHASE2 Type: interventional Locations: Cordova, Tennessee, United States, Honolulu, Hawaii, United States +64 more

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

NCT ID: NCT05508789

The TRAILBLAZER-ALZ 5 trial is studying a medication called donanemab to see if it can help people with early symptoms of Alzheimer’s disease. The goal is to find out how safe the medication is and...

Recruiting

Phase: PHASE3 Type: interventional Locations: Preston, United Kingdom, Box Hill, Victoria, Australia +370 more

HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms

NCT ID: NCT06930560

The HEARS-NPS trial is a study focused on helping older adults with Alzheimer’s Disease and related dementias who also have hearing loss. This trial will test a special hearing care program designe...

Not yet recruiting

Phase: NA Type: interventional

A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)

NCT ID: NCT06223360

The BenfoTeam trial is studying a medication called Benfotiamine to see if it can help slow down the symptoms of early Alzheimer's disease. This study is specifically looking at people aged 50 to 8...

Recruiting

Phase: PHASE2 Type: interventional Locations: Los Angeles, California, United States, Springfield, Illinois, United States +37 more

ADRC Clinical Cohort (Alzheimer's Disease)

NCT ID: NCT06703541

The ADRC Clinical Cohort study is looking at how normal thinking, mild memory problems, and Alzheimer's disease change as people age. The goal is to gather information from a group of participants ...

Recruiting

Type: observational Locations: Durham, North Carolina, United States

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

NCT ID: NCT06937229

The ADAGIO-3 study is a clinical trial focused on testing a new treatment for agitation in people with Alzheimer’s Disease. This trial will specifically look at the long-term effects and safety of ...

Not yet recruiting

Phase: PHASE3 Type: interventional Locations: Athens, Greece, Malaga, Spain +230 more

Cholinergic Deep Brain Stimulation for Alzheimer's Disease

NCT ID: NCT05882344

This clinical trial is exploring a treatment called Deep Brain Stimulation (DBS) to help people with early-stage Alzheimer's disease. Researchers believe that stimulating a specific area of the bra...

Not yet recruiting

Phase: NA Type: interventional Locations: Nashville, Tennessee, United States

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

NCT ID: NCT04123314

This clinical trial is exploring whether psilocybin, a hallucinogenic substance, can help reduce depression in people with Mild Cognitive Impairment (MCI) or early Alzheimer's Disease. The study ai...

Recruiting

Phase: EARLY_PHASE1 Type: interventional Locations: Baltimore, Maryland, United States

A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)

NCT ID: NCT06721156

This clinical trial is studying a new medicine called MK-1167 to see if it can help improve memory and thinking skills in people with Alzheimer's disease dementia. Alzheimer's disease is the most c...

Recruiting

Phase: PHASE2 Type: interventional Locations: Naples, Florida, United States, Sherman Oaks, California, United States +69 more

Effects and Mechanisms of Temporal Interference Brain Stimulation on Memory Function in Preclinical Alzheimer's Disease

NCT ID: NCT07031687

This clinical trial is exploring a new type of brain stimulation called Temporal Interference Brain Stimulation (TIBS) to see if it can help improve memory in people who are in the very early stage...

Recruiting

Phase: NA Type: interventional Locations: Beijing, China, Sanya, Hainan, China

Identification of Diagnosis Biomarkers in the Tears of Alzheimer's Disease Patients: The COG-EYE Pilot Study

NCT ID: NCT06661564

The COG-EYE Pilot Study is a clinical trial aimed at finding new ways to diagnose Alzheimer's disease (AD) by analyzing biomarkers, which are substances that can indicate the presence of the diseas...

Recruiting

Phase: NA Type: interventional Locations: Tours, France

The Role of the Locus Coeruleus in Age-related Distractibility

NCT ID: NCT05574634

This clinical trial is studying how a specific part of the brain called the locus coeruleus (LC) affects our ability to focus, especially as we age. Researchers believe that changes in the connecti...

Recruiting

Phase: NA Type: interventional Locations: Blacksburg, Virginia, United States

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

NCT ID: NCT06297590

This clinical trial is studying a new drug called LY3954068 to see if it is safe for people with early symptoms of Alzheimer’s Disease (AD). The main goals are to check how safe the drug is, how mu...

Recruiting

Phase: PHASE1 Type: interventional Locations: Indianapolis, Indiana, United States, Milwaukee, Wisconsin, United States +16 more

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