Clinical Trials for Alzheimer Disease

Biodistribution of [11C]PIB in Patients With Risk Factors for Alzheimer's Disease

NCT ID: NCT03089827

Brain Energy for Amyloid Transformation in Alzheimer's Disease Study

NCT ID: NCT03472664

The Brain Energy for Amyloid Transformation in Alzheimer's Disease (BEAT-AD) study is investigating how two different diets might affect people with mild cognitive impairment, which is a condition ...

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK

NCT ID: NCT06372821

This clinical trial is studying a new drug called NIO752 to see if it can lower the production of a protein called tau in the brain. Tau is important for keeping nerve cells healthy, but in Alzheim...

Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease

NCT ID: NCT06254469

This clinical trial, called CMK-0301, is designed to study a new imaging technique using a special scan called [F-18]Flornaptitril-PET (F-18 FNT-PET). The goal is to see if this scan can help predi...

I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms in Hispanic Individuals

NCT ID: NCT06099197

The I-CARE 2 clinical trial is looking at a mobile app called Brain CareNotes, which is designed to help Hispanic caregivers of people with Alzheimer's disease and related conditions. The app provi...

Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease

NCT ID: NCT04946916

This clinical trial is studying a specific type of marker called neurofilament light chains to help doctors better understand and differentiate between cognitive and behavioral disorders caused by ...

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

NCT ID: NCT05508789

The TRAILBLAZER-ALZ 5 trial is studying a medication called donanemab to see if it can help people with early symptoms of Alzheimer’s disease. The goal is to find out how safe the medication is and...

A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease

NCT ID: NCT06538116

This clinical trial is studying a new medication called mevidalen (LY3154207) to see if it is safe and effective for people with mild to moderate Alzheimer's disease. The goal is to find out if thi...

Use of Socially Assistive Robots for Long Term Care Older Adults With Cognitive Impairment and Apathy

NCT ID: NCT05178992

This clinical trial is studying how a socially assistive robot can help reduce feelings of apathy in older adults with cognitive impairment, such as those living with Alzheimer's disease. Apathy me...

A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)

NCT ID: NCT06223360

The BenfoTeam trial is studying a medication called Benfotiamine to see if it can help slow down the symptoms of early Alzheimer's disease. This study is specifically looking at people aged 50 to 8...

Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X)

NCT ID: NCT04601038

The CORT-X clinical trial is studying whether a medication called CORT108297 can help reduce the effects of stress on memory and thinking in people with mild cognitive impairment (MCI) related to A...

APOE in the Predisposition to, Protection From, and Prevention of Alzheimer's Disease

NCT ID: NCT04994847

This clinical trial is looking at how changes in the brain are linked to Alzheimer’s disease, which affects memory and thinking skills. Researchers want to understand these changes better so they c...

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

NCT ID: NCT06377033

This clinical trial, titled "Using the EHR to Advance Genomic Medicine Across a Diverse Health System," is exploring a new way to make genetic testing more accessible and useful for patients with c...

Software Validation Study-Cognitive Status Indicator

NCT ID: NCT06809725

The SPARK Cognitive Status Indicator study is testing new software designed to help assess cognitive health, particularly for conditions like Alzheimer’s disease, mild cognitive impairment, and dem...

Senicapoc in Alzheimer's Disease

NCT ID: NCT04804241

This clinical trial is studying a new medication called Senicapoc to see if it can help people in the early stages of Alzheimer's disease, specifically those with mild cognitive impairment or mild ...

Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease

NCT ID: NCT06092125

This clinical trial is looking at a special type of brain scan called PET/MR imaging to help diagnose and treat serious brain conditions like Alzheimer's disease, Parkinson's disease, epilepsy, and...

Frailty Outcomes And Risk With Alzheimer's Related Dementia

NCT ID: NCT06570109

This clinical trial, titled "Frailty and Functional Ability in Alzheimer's," aims to understand how frailty— a condition that often affects older adults— relates to the ability to perform daily tas...

Longitudinal Early-onset Alzheimer's Disease Study Protocol

NCT ID: NCT03507257

The Longitudinal Early-onset Alzheimer's Disease Study (LEADS) is a research study that aims to understand how early onset Alzheimer's disease and related conditions progress over time. The study i...

Alzheimer Prevention Trials (APT) Webstudy

NCT ID: NCT03638583

The Alzheimer Prevention Trials (APT) Webstudy is designed to help researchers find and track people who may be at higher risk for developing Alzheimer's disease (AD) and dementia. The goal is to s...

Novel Personalized Non Invasive Combined Magnetic and Electrical Stimulation of the DMN in Mild AD Patients

NCT ID: NCT07075770

This clinical trial is exploring a new, non-invasive treatment for people with mild Alzheimer’s disease. The treatment uses a special kind of brain stimulation that combines magnetic and electrical...